# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA992487 | B | Inhibition of PCTK2 at 3 uM | 1 | ALA1142492 | single protein format | Scientific Literature | ||
2. | ALA1051349 | B | Binding constant for full-length PCTK2 | Homo sapiens | 38 | ALA1150977 | single protein format | Scientific Literature | |
3. | ALA1057576 | B | Inhibition of PCTK2 assessed as enzyme activity at 1 uM relative to untreated control | 1 | ALA1155237 | single protein format | Scientific Literature | ||
4. | ALA1102994 | B | Inhibition of PCTK2 | 1 | ALA1154951 | single protein format | Scientific Literature | ||
5. | ALA1166610 | B | Inhibition of PCTK2 at 1 uM | 6 | ALA1165965 | single protein format | Scientific Literature | ||
6. | ALA1175186 | B | Inhibition of PCTK2 at 10 uM | 2 | ALA1177794 | single protein format | Scientific Literature | ||
7. | ALA1244556 | B | Binding affinity to PCTK2 | 7 | ALA1240346 | single protein format | Scientific Literature | ||
8. | ALA1827260 | B | Activity of PCTK2 kinase at 1 uM | 1 | ALA1821651 | single protein format | Scientific Literature | ||
9. | ALA1908473 | B | Binding constant for PCTK2 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
10. | ALA1944429 | B | Inhibition of human PCTAIRE2 in HL-60 cells lysate assessed as reduction of labeling of acyl-phosphate ATP probe at 100 nM | Homo sapiens | 4 | ALA1938230 | cell-based format | Scientific Literature | |
11. | ALA2215412 | B | Inhibition of PCTK2 assessed as residual activity at 10 uM relative to control | 1 | ALA2203081 | single protein format | Scientific Literature | ||
12. | ALA2429142 | B | Competitive binding affinity to PCTK2 (unknown origin) at 10 uM in presence of ATP relative to control | Homo sapiens | 3 | ALA2424622 | single protein format | Scientific Literature | |
13. | ALA3111955 | B | Inhibition of PCTK2 (unknown origin) assessed as residual activity at 10 uM after 1 hr by qPCR analysis relative to control | Homo sapiens | 1 | ALA3108735 | single protein format | Scientific Literature | |
14. | ALA3991655 | B | Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. | Homo sapiens | 218 | ALA3991601 | subcellular format | Kuster lab chemical proteomics drug profiling | |
15. | ALA4025293 | B | Inhibition of wild-type human full length PCTK2 (M1 to F523 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4024706 | assay format | Scientific Literature | |
16. | ALA4044104 | B | Inhibition of wild-type human full length PCTK2 (M1 to F523 residues) expressed in Escherichia coli BL21 assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | assay format | Scientific Literature | |
17. | ALA4055116 | B | Inhibition of recombinant human full length PCTAIRE2 (M1 to F523 residues) assessed as residual activity at 50 nM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4052645 | single protein format | Scientific Literature | |
18. | ALA4118444 | B | Inhibition of PCTAIRE2 in human SKCO1 cells at 1 uM after 4 hrs using biotin labeled SKLTENLVALKEIR probe by mass-spectrometric analysis relative to control | Homo sapiens | 3 | ALA4118021 | cell-based format | Scientific Literature | |
19. | ALA4157183 | B | Binding affinity to wild-type human full length PCTK2 (M1 to F523 residues) expressed in bacterial expression system assessed as residual binding at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4152344 | assay format | Scientific Literature | |
20. | ALA4185962 | B | Binding affinity to wild-type human full length PCTK2 (M1 to F523 residues) expressed in Escherichia coli BL21 at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4184148 | assay format | Scientific Literature |