| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA996719 | F | Agonist activity at TLR9 in human PBMC assessed as NF-kappaB activation at 5 ug/mL | Homo sapiens | 2 | ALA1140884 | assay format | Scientific Literature | |
| 2. | ALA997550 | F | Agonist activity at TLR9 in human PBMC assessed as NF-kappaB activation at 100 ug/mL | Homo sapiens | 1 | ALA1140884 | assay format | Scientific Literature | |
| 3. | ALA997551 | F | Antagonist activity at TLR9 in human PBMC assessed as inhibition of 5'-TCTGTCRTTCT-X-TCTTRCTGTCT-5'-induced NF-kappaB activation at 40 ug/mL treated 1 hr before induction measured after 2 hrs | Homo sapiens | 1 | ALA1140884 | assay format | Scientific Literature | |
| 4. | ALA997552 | F | Antagonist activity at TLR9 in human PBMC assessed as inhibition of 5'-UGCUGUUCUG-X-GUCUUGUCGU-5'-induced NF-kappaB activation in human PBMC at 400 ug/mL treated 1 hr before induction measured after 2 hrs | Homo sapiens | 1 | ALA1140884 | assay format | Scientific Literature | |
| 5. | ALA989788 | F | Antagonist activity at human TLR9 expressed in HEK293 cells assessed as blockade of CpG oligonucleotide-induced immune response by NF-kappaB luciferase reporter gene assay | Homo sapiens | 4 | ALA1142478 | cell-based format | Scientific Literature | |
| 6. | ALA1113895 | B | Induction of TLR9-mediated immune stimulation in human PBMC assessed as IL1Ralpha production at 2 ug/ml after 24 hrs by luminex multiplex assay (RVb = 0.12 +/- 0.03 ng/ml) | Homo sapiens | 8 | ALA1157912 | single protein format | Scientific Literature | |
| 7. | ALA1113896 | B | Induction of TLR9-mediated immune stimulation in human PBMC assessed as IL1Ralpha production at 10 ug/ml after 24 hrs by luminex multiplex assay (RVb = 0.12 +/- 0.03 ng/ml) | Homo sapiens | 8 | ALA1157912 | single protein format | Scientific Literature | |
| 8. | ALA1113897 | B | Induction of TLR9-mediated immune stimulation in human PBMC assessed as IL2R production at 2 ug/ml after 24 hrs by luminex multiplex assay (RVb = 0.02 +/- 0.01 ng/ml) | Homo sapiens | 8 | ALA1157912 | single protein format | Scientific Literature | |
| 9. | ALA1113898 | B | Induction of TLR9-mediated immune stimulation in human PBMC assessed as IL2R production at 10 ug/ml after 24 hrs by luminex multiplex assay (RVb = 0.02 +/- 0.01 ng/ml) | Homo sapiens | 8 | ALA1157912 | single protein format | Scientific Literature | |
| 10. | ALA1113899 | B | Induction of TLR9-mediated immune stimulation in human PBMC assessed as IL6 production at 2 ug/ml after 24 hrs by luminex multiplex assay (RVb = 0.01 ng/ml) | Homo sapiens | 8 | ALA1157912 | single protein format | Scientific Literature | |
| 11. | ALA1113900 | B | Induction of TLR9-mediated immune stimulation in human PBMC assessed as IL6 production at 10 ug/ml after 24 hrs by luminex multiplex assay (RVb = 0.01 ng/ml) | Homo sapiens | 8 | ALA1157912 | single protein format | Scientific Literature | |
| 12. | ALA1114639 | B | Induction of TLR9-mediated immune stimulation in human PBMC assessed as IL12 production at 2 ug/ml after 24 hrs by luminex multiplex assay (RVb = 0.00 ng/ml) | Homo sapiens | 8 | ALA1157912 | single protein format | Scientific Literature | |
| 13. | ALA1114640 | B | Induction of TLR9-mediated immune stimulation in human PBMC assessed as IL12 production at 10 ug/ml after 24 hrs by luminex multiplex assay (RVb = 0.00 ng/ml) | Homo sapiens | 8 | ALA1157912 | single protein format | Scientific Literature | |
| 14. | ALA1114641 | B | Induction of TLR9-mediated immune stimulation in human PBMC assessed as MIP1alpha production at 2 ug/ml after 24 hrs by luminex multiplex assay (RVb = 0.01 ng/ml) | Homo sapiens | 8 | ALA1157912 | single protein format | Scientific Literature | |
| 15. | ALA1114642 | B | Induction of TLR9-mediated immune stimulation in human PBMC assessed as MIP1alpha production at 10 ug/ml after 24 hrs by luminex multiplex assay (RVb = 0.01 ng/ml) | Homo sapiens | 8 | ALA1157912 | single protein format | Scientific Literature | |
| 16. | ALA1114643 | B | Induction of TLR9-mediated immune stimulation in human PBMC assessed as MIP1beta production at 2 ug/ml after 24 hrs by luminex multiplex assay (RVb = 0.03 +/- 0.02 ng/ml) | Homo sapiens | 8 | ALA1157912 | single protein format | Scientific Literature | |
| 17. | ALA1114644 | B | Induction of TLR9-mediated immune stimulation in human PBMC assessed as MIP1beta production at 10 ug/ml after 24 hrs by luminex multiplex assay (RVb = 0.03 +/- 0.02 ng/ml) | Homo sapiens | 8 | ALA1157912 | single protein format | Scientific Literature | |
| 18. | ALA1114645 | B | Induction of TLR9-mediated immune stimulation in human PBMC assessed as IP10 production at 2 ug/ml after 24 hrs by luminex multiplex assay (RVb = 0.00 ng/ml) | Homo sapiens | 8 | ALA1157912 | single protein format | Scientific Literature | |
| 19. | ALA1114646 | B | Induction of TLR9-mediated immune stimulation in human PBMC assessed as IP10 production at 10 ug/ml after 24 hrs by luminex multiplex assay (RVb = 0.00 ng/ml) | Homo sapiens | 8 | ALA1157912 | single protein format | Scientific Literature | |
| 20. | ALA1114647 | B | Induction of TLR9-mediated immune stimulation in human PBMC assessed as RANTES production at 2 ug/ml after 24 hrs by luminex multiplex assay (RVb = 0.05 +/- 0.04 ng/ml) | Homo sapiens | 8 | ALA1157912 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!