# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3582684 | Binding | Inverse agonist activity at GAL4-fused human RORa expressed in HEK293T cells assessed as suppression of basal transcriptional activity after 20 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 1 | ALA3580623 | cell-based format | Scientific Literature | |
2. | ALA3586831 | Binding | Inverse agonist activity at human ROR-alpha1 transfected in HEK293 cells at 10 uM after 16 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 6 | ALA3585299 | cell-based format | Scientific Literature | |
3. | ALA3586834 | Binding | Inverse agonist activity at human ROR-alpha1 transfected in HEK293 cells after 16 hrs by luciferase reporter gene assay | Homo sapiens | 4 | ALA3585299 | cell-based format | Scientific Literature | |
4. | ALA3599139 | Binding | Inverse agonist activity at RORalpha (unknown origin) | Homo sapiens | 14 | ALA3596090 | single protein format | Scientific Literature | |
5. | ALA3600176 | Binding | Inverse agonist activity at GAL4-fused human RORa expressed in HEK293T cells assessed as suppression of basal transcriptional activity after 20 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 6 | ALA3596163 | cell-based format | Scientific Literature | |
6. | ALA3598949 | Binding | Inverse agonist activity at Gal4 DNA binding domain-tagged human RORalpha expressed in HEK293T cells assessed as effect on receptor-mediated transcriptional activity by luciferase reporter gene assay | Homo sapiens | 1 | ALA3596154 | cell-based format | Scientific Literature | |
7. | ALA3619501 | Binding | Inverse agonist activity at GAL4-fused human RORa expressed in HEK293 cells assessed as suppression of basal transcriptional activity after 20 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 4 | ALA3616373 | cell-based format | Scientific Literature | |
8. | ALA3776838 | Binding | Inhibition of human RORalpha | Homo sapiens | 1 | ALA3774309 | single protein format | Scientific Literature | |
9. | ALA3784295 | Binding | Inverse agonist activity at human RORalpha transfected in HEK293 cells after 24 hrs by beta galactosidase luciferase reporter gene assay | Homo sapiens | 3 | ALA3779847 | cell-based format | Scientific Literature | |
10. | ALA3796419 | Binding | Inverse agonist activity at human ROR-alpha transfected in HEK293T cells by Gal4 luciferase reporter gene assay | Homo sapiens | 1 | ALA3792338 | cell-based format | Scientific Literature | |
11. | ALA3817091 | Binding | Inhibition of RORalpha receptor (unknown origin) | Homo sapiens | 1 | ALA3813625 | single protein format | Scientific Literature | |
12. | ALA4350008 | Binding | Inhibition of GAL4-DBD fused RORalpha LBD (unknown origin) expressed in HEK293T cells | Homo sapiens | 5 | ALA4346735 | cell-based format | Scientific Literature | |
13. | ALA3385311 | Binding | Inverse agonist activity at RORalpha (unknown origin) by M1H assay | Homo sapiens | 4 | ALA3352412 | single protein format | Scientific Literature | |
14. | ALA3368932 | Binding | Inhibition of RORa (unknown origin) assessed as inhibition of coactivator recruitment by GAL4-nuclear receptor LBD assay | Homo sapiens | 1 | ALA3351629 | single protein format | Scientific Literature | |
15. | ALA3368934 | Binding | Binding affinity to RORa (unknown origin) by radioligand binding assay | Homo sapiens | 1 | ALA3351629 | single protein format | Scientific Literature | |
16. | ALA3368936 | Binding | Binding affinity to RORa-LBD (unknown origin) by radioligand binding assay | Homo sapiens | 1 | ALA3351629 | single protein format | Scientific Literature | |
17. | ALA3367605 | Binding | Inverse agonist activity at GAL4-fused human RORa expressed in HEK293T cells assessed as suppression of basal transcriptional activity after 20 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 5 | ALA3352759 | cell-based format | Scientific Literature | |
18. | ALA3370846 | Binding | Agonist activity at RoRa (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 NR reporter cell-based assay | Homo sapiens | 2 | ALA3351629 | cell-based format | Scientific Literature | |
19. | ALA1738630 | Unassigned | PUBCHEM_BIOASSAY: Late stage results from the probe development effort to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR). (Class of assay: screening) [Related pubchem assays (depositor defined):AID2139, AID2277] Panel member name: RORA | 6 | ALA1201862 | assay format | PubChem BioAssays | ||
20. | ALA974388 | Binding | Activity at RORalpha assessed as coactivator peptide interaction with receptor ligand binding domain by FRET assay | 1 | ALA1136905 | single protein format | Scientific Literature |