| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA993711 | B | Inhibition of HSF1 binding to heat shock element DNA assessed as HSF1/HSE complex formation in human HeLa cells at 50 ug/mL treated for 1 hr before heat induction | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA993712 | B | Inhibition of HSF1 binding to heat shock element DNA assessed as HSF1/HSE complex formation in human Jurkat cells at 50 ug/mL treated for 1 hr before heat induction | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA1060467 | B | Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challenge measured after 2 hrs by immunocytochemical staining | Homo sapiens | 44 | cell-based format | Scientific Literature | ||
| 4. | ALA1060469 | B | Transcriptional activation of HSF1 in human HeLa cells assessed as granule formation treated 3 hrs before heat shock challenge by immunocytochemical staining | Homo sapiens | 46 | cell-based format | Scientific Literature | ||
| 5. | ALA1051570 | B | Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation at 80 uM treated 1 hr before heat shock challenge measured after 2 hrs by immunocytochemical staining | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA1063218 | B | Amplification of HSF1 transcriptional activity in human HeLa cells assessed as granule formation pretreated for 3 hrs by immunocytochemical staining | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 7. | ALA1063219 | B | Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock challenge measured after 2 hrs without recovery time by immunocytochemical staining | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 8. | ALA1063232 | B | Amplification of HSF1 transcriptional activity in human HeLa cells assessed as HFS1 granule count at 80 uM by immunocytochemical staining | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3295291 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of hsp25 promoter activity after 12 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3295292 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of hsp70 promoter activity after 12 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3295295 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP27 mRNA expression at 1 to 20 uM after 12 hrs by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3295296 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP70 mRNA expression at 1 to 20 uM after 12 hrs by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3295297 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP1 mRNA expression at 1 to 20 uM after 12 hrs by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3295298 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP27 mRNA expression at 20 uM up to 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3295299 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP70 mRNA expression at 20 uM up to 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3295300 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP1 mRNA expression at 20 uM up to 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3295301 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP25 protein expression after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3295302 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP70 protein expression after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3295555 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP1 protein expression after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3295556 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP25 protein expression at 20 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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