# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3587752 | Binding | Inhibition of HSP27 (unknown origin) by insulin aggregation assay | Homo sapiens | 1 | ALA3585286 | single protein format | Scientific Literature | |
2. | ALA4362126 | Binding | Effect on HSP27 at S78/S82 phosphorylation level in human NCI-H1975 incubated for 12 hrs by human phosphokinase proteome profiler array relative to control | Homo sapiens | 2 | ALA4359863 | cell-based format | Scientific Literature | |
3. | ALA4362165 | Binding | Effect on HSP27 at S78/S82 phosphorylation level in human NCI-H1975 incubated for 12 hrs by human phosphokinase proteome profiler array relative to beta-catenin | Homo sapiens | 2 | ALA4359863 | cell-based format | Scientific Literature | |
4. | ALA987300 | Binding | Inhibition of HSP27 phosphorylation in IL-1-alpha-stimulated HLF cells | Homo sapiens | 6 | ALA1155813 | cell-based format | Scientific Literature | |
5. | ALA993710 | Binding | Enhancement of HSP27 Ser78 phosphorylation in human HeLa cells at 50 ug/mL treated for 1 hr | Homo sapiens | 11 | ALA1153987 | cell-based format | Scientific Literature | |
6. | ALA955776 | Binding | Inhibition of LPS-stimulated hsp27 phosphorylation in 1 hr pretreated human THP1 cells by Western blot | Homo sapiens | 2 | ALA1152141 | cell-based format | Scientific Literature | |
7. | ALA2060020 | Binding | Binding affinity to Hsp27 in human SKBR3 cell lysate at 25 uM after 30 mins by mass spectrometric analysis | Homo sapiens | 1 | ALA2057143 | cell-based format | Scientific Literature | |
8. | ALA2060023 | Binding | Binding affinity to pure Hsp27 in human SKBR3 cell lysate at 25 to 50 uM after 1 hr by Western blot analysis | Homo sapiens | 1 | ALA2057143 | cell-based format | Scientific Literature | |
9. | ALA2060030 | Binding | Induction of Hsp27 phosphorylation in human SKBR3 cells at 0.2 to 1 uM after 24 hrs by SDS-PAGE analysis | Homo sapiens | 2 | ALA2057143 | cell-based format | Scientific Literature | |
10. | ALA2060031 | Binding | Inhibition of Hsp27 phosphorylation in human SKBR3 cells at 0.5 to 1 uM after 24 hrs by immunofluorescence analysis | Homo sapiens | 1 | ALA2057143 | cell-based format | Scientific Literature | |
11. | ALA2060033 | Binding | Binding affinity to pure Hsp27 in human SKBR3 cell lysate at 0.5 to 1 uM after 1 hr by Western blot analysis | Homo sapiens | 1 | ALA2057143 | cell-based format | Scientific Literature | |
12. | ALA2060036 | Binding | Induction of Hsp27 phosphorylation in human SKBR3 cells at 50 to 100 nM after 24 hrs by SDS-PAGE analysis | Homo sapiens | 1 | ALA2057143 | cell-based format | Scientific Literature | |
13. | ALA2399253 | Binding | Inhibition of HSP27 (unknown origin) assessed as increase in DTT-induced insulin B chain aggregation at 5 uM incubated for 5 mins prior to DTT-treatment measured after 30 mins by spectrophotometric analysis relative to control | Homo sapiens | 1 | ALA2396529 | single protein format | Scientific Literature | |
14. | ALA2399958 | Binding | Inhibition of HSP27 (unknown origin) assessed as increase in DTT-induced insulin B chain aggregation at 10 uM incubated for 5 mins prior to DTT-treatment measured after 30 mins by spectrophotometric analysis relative to control | Homo sapiens | 5 | ALA2396529 | single protein format | Scientific Literature | |
15. | ALA4026126 | Binding | Inhibition of heat shock protein 27 in human LNCaP cells assessed as decrease in AR protein level at 200 uM after 48 hrs by Western blot method | Homo sapiens | 3 | ALA4024729 | cell-based format | Scientific Literature | |
16. | ALA4026127 | Binding | Inhibition of heat shock protein 27 in human LNCaP cells assessed as decrease in AR protein level at 20 uM after 48 hrs by Western blot method | Homo sapiens | 7 | ALA4024729 | cell-based format | Scientific Literature | |
17. | ALA4026128 | Binding | Inhibition of heat shock protein 27 in human LNCaP cells assessed as decrease in AR protein level after 48 hrs by Western blot method | Homo sapiens | 2 | ALA4024729 | cell-based format | Scientific Literature | |
18. | ALA4026130 | Binding | Inhibition of heat shock protein 27 in human LNCaP cells assessed as decrease in AR protein level at 5 uM after 48 hrs by Western blot method | Homo sapiens | 1 | ALA4024729 | cell-based format | Scientific Literature | |
19. | ALA4133455 | Binding | Induction of abnormal HSP27 dimerization in human NCI-H460 cells at 10 uM co-treated with 17-AAG after 24 hrs by Western blot analysis | Homo sapiens | 4 | ALA4130424 | cell-based format | Scientific Literature | |
20. | ALA4133456 | Binding | Induction of abnormal HSP27 dimerization in human NCI-H460 cells at 10 uM after 12 hrs by Western blot analysis | Homo sapiens | 4 | ALA4130424 | cell-based format | Scientific Literature |