# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA869056 | A | Inhibition of rat liver CYP2E1 | Rattus norvegicus | 6 | ALA1138063 | tissue-based format | Scientific Literature | |
2. | ALA1015214 | A | Inhibition of CYP2E1 in acetone-treated Sprague-Dawley rat liver microsomes assessed as hydroxylation of p-nitrophenol by spectrophotometry | Rattus norvegicus | 11 | ALA1152815 | microsome format | Scientific Literature | |
3. | ALA1908251 | A | Mechanism based inhibition of rabbit cytochrome P450 CYP2E1 measured by 7-EFC O-deethylation activity | Oryctolagus cuniculus | 2 | ALA1743341 | single protein format | Scientific Literature | |
4. | ALA1908252 | A | Mechanism based inhibition of rabbit cytochrome P450 CYP2E1 measured by P-nitrophenol (PNP) hydroxylase activity | Oryctolagus cuniculus | 1 | ALA1743341 | single protein format | Scientific Literature | |
5. | ALA1908271 | A | Mechanism based inhibition of rat cytochrome P450 CYP2E1 | Rattus norvegicus | 4 | ALA1743341 | single protein format | Scientific Literature | |
6. | ALA1908272 | A | Mechanism based inhibition of rat cytochrome P450 CYP2E1 measured by P-nitrophenol (PNP) hydroxylase activity | Rattus norvegicus | 1 | ALA1743341 | single protein format | Scientific Literature | |
7. | ALA3536079 | A | Drug metabolism in rat recombinant CYP2E1 assessed as (Z)-N'-hydroxy-6-(5-(5-((Z)-N'-methoxycarbamimidoyl)pyridin-2-yl)furan-2-yl nicotinimidamide formation treated with DB868 | Rattus norvegicus | 1 | ALA3525966 | assay format | Scientific Literature | |
8. | ALA3536452 | A | Drug metabolism in rat recombinant CYP2E1 assessed as (3Z,3'Z)-6,6'-(furan-2,5-diyl)bis(N'-hydroxynicotinimidamide) formation treated with DB868 | Rattus norvegicus | 1 | ALA3525966 | assay format | Scientific Literature | |
9. | ALA3784250 | A | Drug metabolism in rat liver microsomes assessed as CYP2E1 mediated metabolite M4 formation at 10 uM preincubated for 5 mins followed by addition of NADPH measured after 120 mins by HPLC-TIC chromatography in presence of clomethiazole | Rattus norvegicus | 1 | ALA3779870 | tissue-based format | Scientific Literature | |
10. | ALA3784372 | A | Drug metabolism in rat liver microsomes assessed as CYP2E1 mediated metabolite M4 formation at 10 uM preincubated for 5 mins followed by addition of NADPH measured after 120 mins by HPLC-TIC chromatography in presence of CYP1A2 inhibitor alpha-naphthoflavone, CYP2C8 inhibitor quercetin, CYP2C9 inhibitor sulfaphenazole, CYP2C19 inhibitor ticlopidine, CYP2D6 inhibitor quinidine, CYP3A inhibitor ketoconazole | Rattus norvegicus | 1 | ALA3779870 | tissue-based format | Scientific Literature | |
11. | ALA3782859 | A | Drug metabolism in rat liver microsomes assessed as CYP2E1 mediated metabolite M4 formation at 10 uM preincubated for 5 mins followed by addition of NADPH measured after 120 mins by HPLC-TIC chromatography in presence of ketoconazole | Rattus norvegicus | 1 | ALA3779870 | tissue-based format | Scientific Literature | |
12. | ALA5118025 | A | Inhibition of CYP2E1 in rat liver microsomes using chlorzoxazone as substrate | Rattus norvegicus | 1 | ALA5113488 | microsome format | Scientific Literature |