# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA714719 | B | Ability to inhibit 2-[125I]iodomelatonin specific binding to melatonin receptor 3 (MT3) of Syrian hamster brain. | Cricetulus griseus | 35 | ALA1135781 | assay format | Scientific Literature | |
2. | ALA713109 | B | Inhibition of 2-[125I]iodomelatonin binding to Melatonin receptor 3 (MT3) of Syrian hamster brain membrane | 12 | ALA1135933 | assay format | Scientific Literature | ||
3. | ALA1016924 | B | Displacement of [125I]iodomelatonin from MT3/QR2 melatonin binding site expressed in CHO cells | 39 | ALA1154476 | cell-based format | Scientific Literature | ||
4. | ALA960909 | B | Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) incubated at 23 degC by MTT assay | Homo sapiens | 23 | ALA1153344 | assay format | Scientific Literature | |
5. | ALA1065027 | B | Inhibition of human recombinant NQO2 by spectrophotometry | Homo sapiens | 16 | ALA1159058 | single protein format | Scientific Literature | |
6. | ALA1109212 | B | Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry | Homo sapiens | 18 | ALA1157906 | single protein format | Scientific Literature | |
7. | ALA1175843 | B | Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) by UV-vis microplate reader analysis | Homo sapiens | 2 | ALA1177666 | assay format | Scientific Literature | |
8. | ALA1248886 | B | Binding affinity to ML2 (MT3) receptor by radioligand displacement assay | 2 | ALA1240489 | single protein format | Scientific Literature | ||
9. | ALA1291625 | B | Inhibition of human recombinant NQO2 | Homo sapiens | 36 | ALA1287791 | single protein format | Scientific Literature | |
10. | ALA1291627 | B | Inhibition of human recombinant NQO2 at 100 uM | Homo sapiens | 59 | ALA1287791 | single protein format | Scientific Literature | |
11. | ALA1693919 | B | Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) assessed as N-methyldihydronicotinamide oxidation per mg of protein after 1 hr by LC-MS analysis analysis | Homo sapiens | 2 | ALA1687868 | assay format | Scientific Literature | |
12. | ALA1772363 | B | Binding affinity to human low affinity melatonin (MT3) site of quinone reductase 2 | Homo sapiens | 9 | ALA1770106 | single protein format | Scientific Literature | |
13. | ALA1772366 | B | Ratio of compound IC50 to MCA-NAT IC50 for human low affinity melatonin (MT3) site of quinone reductase 2 | Homo sapiens | 1 | ALA1770106 | single protein format | Scientific Literature | |
14. | ALA1772367 | B | Binding affinity to low affinity melatonin (MT3) site of quinone reductase 2 | 3 | ALA1770106 | single protein format | Scientific Literature | ||
15. | ALA1805489 | B | Inhibition of human QR2 expressed in Escherichia coli BL21 (DE3) using MTT and NMeH as substrate assessed as formazan formation | Homo sapiens | 32 | ALA1800051 | assay format | Scientific Literature | |
16. | ALA1805496 | B | Inhibition of human QR2 expressed in Escherichia coli BL21 (DE3) at 50 uM using MTT and NMeH as substrate assessed as formazan formation | Homo sapiens | 31 | ALA1800051 | assay format | Scientific Literature | |
17. | ALA1805497 | B | Inhibition of human QR2 expressed in Escherichia coli BL21 (DE3) at 100 uM using MTT and NMeH as substrate assessed as formazan formation | Homo sapiens | 1 | ALA1800051 | assay format | Scientific Literature | |
18. | ALA1837963 | B | Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry | Homo sapiens | 19 | ALA1833815 | single protein format | Scientific Literature | |
19. | ALA1837970 | B | Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry in the presence of 2 uM BSA | Homo sapiens | 2 | ALA1833815 | single protein format | Scientific Literature | |
20. | ALA1837971 | B | Ratio of IC50 for human recombinant NQO2 in the presence of BSA to IC50 for human recombinant NQO2 in the absence of BSA | Homo sapiens | 4 | ALA1833815 | single protein format | Scientific Literature |