# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA906609 | F | Protective effect against alphaSyn mediated toxicity in wild-type transgenic Drosophila expressing elav-GAL4; UAS-synWT assessed as rescue of dorsomedial neurons after drug administration for the first 20 days of adult life | Drosophila | 1 | organism-based format | Scientific Literature | ||
2. | ALA929290 | A | Toxicity in drosophila Huntington's disease model | Drosophila | 3 | organism-based format | Scientific Literature | ||
3. | ALA929292 | F | Decrease in rhabdomere degeneration in Drosophila photoreceptor assessed as number of rhabdomeres per ommatidium at day 9 | Drosophila | 1 | organism-based format | Scientific Literature | ||
4. | ALA924809 | F | Cell death rescue of neuronal cells in drosophila Huntington's disease model | Drosophila | 3 | organism-based format | Scientific Literature | ||
5. | ALA1028179 | F | Reduction on lethality of Drosophila UAS-APP/UAS-APP; UAS-BACE523/UAS-BACE523 flies expressing BACE mutant assessed as increase in survival by measuring eclosion numbers 4 mM dosed in diet | Drosophila | 1 | organism-based format | Scientific Literature | ||
6. | ALA1028181 | F | Reduction on lethality of Drosophila w:actin-GAL4/Cyo;UASDPsn/Tm3 flies expressing presenilin mutant assessed as increase in survival by measuring eclosion numbers 4 mM dosed in diet | Drosophila | 1 | organism-based format | Scientific Literature | ||
7. | ALA1099975 | F | Short term memory enhancement in human Abeta42 transgenic Drosophila alzheimers disease model dosed for 6 days by pavlovian olfactory learning assay after 8 days | Drosophila | 8 | organism-based format | Scientific Literature | ||
8. | ALA1220855 | F | Protection against fragile X syndrome phenotypes in Fmr1 null mutant Drosophila Fmr1'3/TM6C assessed as embryo viability at 40 uM at 25 degC by flow cytometry relative to untreated homozygous embryos | Drosophila | 15 | organism-based format | Scientific Literature | ||
9. | ALA1220856 | F | Protection against fragile X syndrome phenotypes in laboratory prepared food feeded Fmr1 null mutant Drosophila Fmr1'3/TM6C assessed as homozygous Fmr1-/- embryo viability at 40 uM at 25 degC by flow cytometry relative to untreated homozygous embryos fed with only laboratory prepared food | Drosophila | 5 | organism-based format | Scientific Literature | ||
10. | ALA1220857 | F | Protection against fragile X syndrome phenotypes in laboratory prepared food feeded Fmr1 null mutant Drosophila Fmr1'3/TM6C assessed as homozygous Fmr1-/- embryo viability at 20 uM at 25 degC by flow cytometry relative to untreated homozygous embryos fed with only laboratory prepared food | Drosophila | 1 | organism-based format | Scientific Literature | ||
11. | ALA1220858 | F | Protection against fragile X syndrome phenotypes in laboratory prepared food feeded Fmr1 null mutant Drosophila Fmr1'3/TM6C assessed as homozygous Fmr1-/- embryo viability at 5 uM at 25 degC by flow cytometry relative to untreated homozygous embryos fed with only laboratory prepared food | Drosophila | 2 | organism-based format | Scientific Literature | ||
12. | ALA1220859 | F | Protection against fragile X syndrome phenotypes in laboratory prepared food feeded Fmr1 null mutant Drosophila Fmr1'3/TM6C assessed as homozygous Fmr1-/- embryo viability at 10 uM at 25 degC by flow cytometry relative to untreated homozygous embryos fed with only laboratory prepared food | Drosophila | 2 | organism-based format | Scientific Literature | ||
13. | ALA1220860 | F | Cytoprotection against glutamate-induced toxicity in laboratory prepared food feeded Fmr1 null mutant Drosophila Fmr1'3/TM6C fragile X syndrome model assessed as embryo viability at 80 uM by flow cytometry relative to untreated embryos | Drosophila | 1 | organism-based format | Scientific Literature | ||
14. | ALA1220861 | F | Cytoprotection against glutamate-induced toxicity in laboratory prepared food feeded Fmr1 null mutant Drosophila Fmr1'3/TM6C fragile X syndrome model assessed as genetic segregation ratio at 40 uM by flow cytometry relative to untreated embryos | Drosophila | 1 | organism-based format | Scientific Literature | ||
15. | ALA1220862 | F | Cytoprotection against glutamate-induced toxicity in laboratory prepared food feeded Fmr1 null mutant Drosophila Fmr1'3/TM6C fragile X syndrome model assessed as embryo viability at 40 uM by flow cytometry relative to untreated embryos | Drosophila | 2 | organism-based format | Scientific Literature | ||
16. | ALA1220863 | F | Cytoprotection against glutamate-induced toxicity in laboratory prepared food feeded Fmr1 null mutant Drosophila Fmr1'3/TM6C fragile X syndrome model assessed as embryo viability at 40 uM in presence of GABAB receptor antagonist CGP-54626 by flow cytometry relative to untreated embryos | Drosophila | 1 | organism-based format | Scientific Literature | ||
17. | ALA1220864 | F | Suppression of glutamate-induced Futsch protein overexpression in head lysates of laboratory prepared food feeded Fmr1 null mutant Drosophila Fmr1'3/TM6C fragile X syndrome model at 40 uM by Western blot | Drosophila | 1 | organism-based format | Scientific Literature | ||
18. | ALA1220865 | F | Suppression of Futsch protein overexpression in head lysates of laboratory prepared food feeded Fmr1 null mutant Drosophila Fmr1'3/TM6C fragile X syndrome model at 40 uM by Western blot | Drosophila | 4 | organism-based format | Scientific Literature | ||
19. | ALA1220866 | F | Suppression of Futsch protein overexpression in head lysates of laboratory prepared food feeded Fmr1 null mutant Drosophila Fmr1'3/TM6C fragile X syndrome model at 40 uM in presence of Scopolamine by Western blot | Drosophila | 1 | organism-based format | Scientific Literature | ||
20. | ALA1220867 | F | Suppression of glutamate-induced beta-lobe midline crossing deffect in mushroom bodies of laboratory prepared food feeded Fmr1 null mutant Drosophila Fmr1'3/TM6C fragile X syndrome model at 40 uM by Fas2 staining based confocal microscopy | Drosophila | 1 | organism-based format | Scientific Literature |