# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA700522 | F | Ability to open cloned mKCNQ2 channel expressed in Xenopus laevis oocytes at 10 uM expressed as percent of compound-free control current at -40 mV | 26 | ALA1149174 | cell-based format | Scientific Literature | ||
2. | ALA700523 | F | Increased outward current at -40 mV mediated by mouse KCNQ2 channel expressed in Xenopus laevis oocytes | Mus musculus | 1 | ALA1148224 | cell-based format | Scientific Literature | |
3. | ALA700524 | F | Increased outward current at -40 mV mediated by mouse KCNQ2 channel expressed in Xenopus laevis oocytes at 100 nM | Mus musculus | 1 | ALA1148224 | cell-based format | Scientific Literature | |
4. | ALA700525 | F | Increased outward current at -40 mV mediated by mouse KCNQ2 channel expressed in Xenopus laevis oocytes at 1 uM | Mus musculus | 3 | ALA1148224 | cell-based format | Scientific Literature | |
5. | ALA700526 | F | Increased outward current at -40 mV mediated by mouse KCNQ2 channel expressed in Xenopus laevis oocytes at 20 uM | Mus musculus | 11 | ALA1148224 | cell-based format | Scientific Literature | |
6. | ALA700527 | F | Increased outward current at -40 mV mediated by mouse KCNQ2 channel expressed in Xenopus laevis oocytes at 20 uM; Insoluble | Mus musculus | 1 | ALA1148224 | cell-based format | Scientific Literature | |
7. | ALA700528 | F | Increased outward current at -40 mV mediated by mouse KCNQ2 channel expressed in Xenopus laevis oocytes at 5 uM; Insoluble | Mus musculus | 1 | ALA1148224 | cell-based format | Scientific Literature | |
8. | ALA700529 | F | Efficacy for mKCNQ2 expressed in HEK293 cells relative to reference compound | Mus musculus | 6 | ALA1147528 | cell-based format | Scientific Literature | |
9. | ALA700530 | F | Whole-cell patch-clamp on recombinant mouse KCNQ2 channels expressed in HEK 293 cells at -40 mV | Mus musculus | 6 | ALA1147528 | cell-based format | Scientific Literature | |
10. | ALA824615 | F | Threshold for augmenting KCNQ2 current in HEK 293 stable cell line expressing mKCNQ2 channel | Mus musculus | 1 | ALA1145847 | cell-based format | Scientific Literature | |
11. | ALA821683 | F | Induced current in Xenopus laevis oocytes expressing cloned mKCNQ2 channels | Mus musculus | 1 | ALA1145847 | cell-based format | Scientific Literature | |
12. | ALA838011 | F | Effect on outward potassium currents in whole-cell patch clamp assay of HEK 293 cells expressing cloned mouse KCNQ2 channel at -40 mV | 10 | ALA1142835 | cell-based format | Scientific Literature | ||
13. | ALA836871 | F | Relative efficacy as ratio of maximal current amplitudes for compound and reference | 10 | ALA1142835 | assay format | Scientific Literature | ||
14. | ALA2444335 | B | Induction of mouse KCNQ2 expressed in HEK293 cells at -40 mV holding potential by whole-cell patch clamp assay relative to retigabine | Mus musculus | 1 | ALA2439980 | cell-based format | Scientific Literature | |
15. | ALA2444336 | B | Induction of mouse KCNQ2 expressed in HEK293 cells at -40 mV holding potential by whole-cell patch clamp assay relative to (+/-)-N-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)-3-(2-chlorophenyl)acrylamide | Mus musculus | 7 | ALA2439980 | cell-based format | Scientific Literature | |
16. | ALA2444337 | B | Induction of mouse KCNQ2 expressed in HEK293 cells at -40 mV holding potential by whole-cell patch clamp assay | Mus musculus | 9 | ALA2439980 | cell-based format | Scientific Literature |