Antimycobacterial activity in Mycobacterium ulcerans Cu001 infected BALB/c mouse assessed as mean number of CFU per foot-pad at 10 mg/kg, sc after 2 weeks
Antimycobacterial activity in Mycobacterium ulcerans Cu001 infected BALB/c mouse assessed as mean number of CFU per foot-pad at 150 mg, sc after 2 weeks
Antimycobacterial activity against Mycobacterium ulcerans isolate CU001 infected in BALB/c mouse left hind foot-pad assessed as bacterial load per culture-positive foot-pad at 10 mg/kg, po administered for 5 days per week measured after 4 weeks
Antimycobacterial activity against Mycobacterium ulcerans isolate CU001 infected in BALB/c mouse left hind foot-pad assessed as bacterial load per culture-positive foot-pad at 100 mg/kg, po administered for 5 days per week measured after 4 weeks
Antimycobacterial activity against Mycobacterium ulcerans isolate CU001 infected in BALB/c mouse left hind foot-pad assessed as bacterial load per culture-positive foot-pad at 10 mg/kg, po administered for 5 days per week measured after 8 weeks
Antimycobacterial activity against Mycobacterium ulcerans isolate CU001 infected in BALB/c mouse left hind foot-pad assessed as bacterial load at 10 mg/kg, po administered for 5 days per week measured after 4 weeks
Antimycobacterial activity against Mycobacterium ulcerans isolate CU001 infected in BALB/c mouse left hind foot-pad assessed as bacterial load at 100 mg/kg, po administered for 5 days per week measured after 4 weeks
Antimycobacterial activity against Mycobacterium ulcerans isolate CU001 infected in BALB/c mouse left hind foot-pad assessed as incidence of bacterial infection at 10 mg/kg, po administered for 5 days per week measured after 8 weeks
Antimycobacterial activity against Mycobacterium ulcerans isolate CU001 infected in BALB/c mouse left hind foot-pad assessed as incidence of bacterial infection at 100 mg/kg, po administered for 5 days per week measured after 8 weeks
Antimycobacterial activity against Mycobacterium ulcerans isolate CU001 infected in BALB/c mouse left hind foot-pad assessed as bacterial load at 10 mg/kg, po administered for 5 days per week measured after 8 weeks
Antimycobacterial activity against Mycobacterium ulcerans isolate CU001 infected in BALB/c mouse left hind foot-pad assessed as bacterial load at 100 mg/kg, po administered for 5 days per week measured after 8 weeks
Antimicrobial activity against Mycobacterium ulcerans ATCC 19423 harboring pTY60H containing pCK0601 carrying the luxAB gene under the hsp60 promoter after 14 days determined according to CFU counts by bioluminescence method
Antimicrobial activity against Mycobacterium ulcerans 1059 harboring pTY60K containing pMH94 carrying the luxAB gene under the hsp60 promoter after 14 days determined according to CFU count by bioluminescence method
Antimicrobial activity against Mycobacterium ulcerans ATCC 19423 harboring pTY60K containing pMH94 carrying the luxAB gene under the hsp60 promoter after 7 days determined according to CFU count by bioluminescence method
Antimicrobial activity against Mycobacterium ulcerans ATCC 19423 harboring pTY60H carrying the luxAB gene under the hsp60 promoter determined after 14 days in presence of 2.5 ug/ml ATP-cassette transporter inhibitor reserpine
Antimicrobial activity against Mycobacterium ulcerans ATCC 19423 harboring pTY60H assessed as 2-fold increase in reserpine-mediated inhibition of bacterial growth after 14 days
Antimicrobial activity against Mycobacterium ulcerans ATCC 19423 harboring pTY60H assessed as 4-fold increase in reserpine-mediated inhibition of bacterial growth after 14 days