# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA706379 | B | inhibitory activity against Human Lactate Dehydrogenase (LDH-H) | 10 | single protein format | Scientific Literature | |||
2. | ALA706380 | B | inhibitory activity against Human Lactate Dehydrogenase (LDH-M) | 10 | single protein format | Scientific Literature | |||
3. | ALA2060672 | B | Inhibition of human recombinant LDHB (2 to 334 amino acid residue) expressed in Escherichia coli BL21 (DE3) cells after 10 mins by spectrophotometric analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
4. | ALA1692977 | B | Inhibition of human LDH-B using pyruvate as substrate and NADH as cofactor at 125 uM after 5 mins by calorimetric assay relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
5. | ALA1692978 | B | Inhibition of human LDH-B using saturating concentration of pyruvate and NADH as cofactor after 5 mins by calorimetric assay relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
6. | ALA2384178 | B | Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in insect cells using pyruvate as substrate after 10 mins by UV endpoint analysis | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
7. | ALA2432256 | B | Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as disappearance of NADH after 10 mins by fluorescence assay | Homo sapiens | 33 | assay format | Scientific Literature | ||
8. | ALA3107144 | B | Inhibition of LDHB (unknown origin) using sodium pyruvate as substrate at 0.46 to 57.5 uM after 15 mins by fluorescence assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
9. | ALA3386530 | B | Inhibition of LDHB (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
10. | ALA3369988 | B | Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assay | Homo sapiens | 25 | single protein format | Scientific Literature | ||
11. | ALA3562094 | F | PubChem BioAssay. Extended Characterization of HPGD Inhibitors: Counterscreen Against LDHB. (Class of assay: confirmatory) | Homo sapiens | ⋯ | assay format | PubChem BioAssays | ||
12. | ALA3583865 | B | Inhibition of LDH-B (unknown origin) | Homo sapiens | 7 | single protein format | Scientific Literature | ||
13. | ALA3768544 | B | Competitive inhibition of human LDH1 meaured for 3 mins in presence of NADH by fluorescence analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
14. | ALA3768755 | B | Competitive inhibition of human LDH1 meaured for 3 mins in presence of pyruvate by fluorescence analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
15. | ALA3768757 | B | Competitive inhibition of human LDH1 in presence of NADH | Homo sapiens | 22 | single protein format | Scientific Literature | ||
16. | ALA4032332 | B | Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence assay | Homo sapiens | 21 | assay format | Scientific Literature | ||
17. | ALA4257798 | B | Inhibition of human LDHB | Homo sapiens | 1 | single protein format | Scientific Literature | ||
18. | ALA4405874 | B | Competitive binding affinity to recombinant full length human His-tagged LDH-1 (1 to 322 residues) expressed in Escherichia coli assessed as protein-compound interaction at N-terminal domain after 5 mins by Red-NHS fluorescence dye based microscale thermophoresis analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
19. | ALA4405875 | B | Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) measured after 5 mins by Red-NHS fluorescent dye based microscale thermophoresis analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
20. | ALA4405876 | B | Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) assessed as saturation transfer stemming at 800 uM in sodium phosphate buffer at pH 7.6 by WaterLOGSY NMR analysis | Homo sapiens | 1 | assay format | Scientific Literature |