# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3606935 | Binding | Inhibition of human MTAP using methylthioadenosine as substrate by xanthine oxidase coupling enzyme assay | Homo sapiens | 2 | ALA3603762 | single protein format | Scientific Literature | |
2. | ALA3606936 | Binding | Inhibition of human MTAP using methylthioadenosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-inhibitor complex by xanthine oxidase coupling enzyme assay | Homo sapiens | 1 | ALA3603762 | single protein format | Scientific Literature | |
3. | ALA3755835 | ADME | Prodrug activation assessed as recombinant human MTAP-mediated compound cleavage at 100 uM by reverse phase HPLC analysis | Homo sapiens | 4 | ALA3751814 | single protein format | Scientific Literature | |
4. | ALA615268 | Binding | Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylase | 10 | ALA1149178 | single protein format | Scientific Literature | ||
5. | ALA615269 | Binding | Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylase; nd = Not determined | 6 | ALA1149178 | single protein format | Scientific Literature | ||
6. | ALA615270 | Binding | Initial dissociation constant towards human 5'-methylthioadenosine phosphorylase | 16 | ALA1149178 | single protein format | Scientific Literature | ||
7. | ALA713611 | Binding | Inhibitory concentration against Methylthioadenosine phosphorylase | 1 | ALA1149090 | single protein format | Scientific Literature | ||
8. | ALA827883 | Binding | Inhibition of human MTAP as initial dissociation constant | Homo sapiens | 18 | ALA1140320 | single protein format | Scientific Literature | |
9. | ALA827232 | Binding | Km for human MTAP | Homo sapiens | 1 | ALA1140320 | single protein format | Scientific Literature | |
10. | ALA827246 | Binding | Km against human methylthioadenosine phosphorylase expressed in Escherichia coli BL21 DE3 cells | Homo sapiens | 32 | ALA1139590 | cell-based format | Scientific Literature | |
11. | ALA827266 | Binding | Km against human methylthioadenosine phosphorylase expressed in Escherichia coli BL21 DE3 cells; Not determined | Homo sapiens | 1 | ALA1139590 | cell-based format | Scientific Literature | |
12. | ALA828333 | Binding | Inhibition of human MTAP as equilibrium dissociation constant | Homo sapiens | 16 | ALA1140320 | single protein format | Scientific Literature | |
13. | ALA828334 | Binding | Inhibition of human MTAP as equilibrium dissociation constant; ND=no slow-onset phase | Homo sapiens | 2 | ALA1140320 | single protein format | Scientific Literature | |
14. | ALA828699 | Binding | Kcat against human methylthioadenosine phosphorylase expressed in Escherichia coli BL21 DE3 cells | Homo sapiens | 33 | ALA1139590 | cell-based format | Scientific Literature | |
15. | ALA829265 | Binding | Ratio of Kcat to Km against human Methylthioadenosine phosphorylase | Homo sapiens | 32 | ALA1139590 | single protein format | Scientific Literature | |
16. | ALA831698 | Binding | Ratio of Kcat to Km against human Methylthioadenosine phosphorylase; Not determined | Homo sapiens | 1 | ALA1139590 | single protein format | Scientific Literature | |
17. | ALA1244606 | Binding | Inhibition of MTAP in human FaDu cells by ESI-MS analysis | Homo sapiens | 1 | ALA1240343 | cell-based format | Scientific Literature | |
18. | ALA1244607 | Binding | Inhibition of MTAP in human CRL2522 cells by by ESI-MS analysis | Homo sapiens | 1 | ALA1240343 | cell-based format | Scientific Literature | |
19. | ALA1246404 | Binding | Inhibition of His-tagged human MTAP | Homo sapiens | 14 | ALA1240514 | single protein format | Scientific Literature | |
20. | ALA1246406 | Binding | Inhibition of His-tagged human MTAP at 2.5 uM | Homo sapiens | 1 | ALA1240514 | single protein format | Scientific Literature |