Antimalarial activity against Plasmodium vinckei petteri infected mice (Mus musculus) at 13 mg/kg/day, peroral administered 4 days after infection for 4 days
Antimalarial activity against Plasmodium vinckei petteri infected mice (Mus musculus) at 5 mg/kg/day, peroral administered 4 days after infection for 4 days
Antiplasmodial activity Plasmodium vinckei petteri infected in CD mouse assessed as suppression of parasitaemia at 10 mg/kg/day, ip administered from day 0 to day 3 and measured on day 4 by Giemsa staining relative to control
Antiplasmodial activity Plasmodium vinckei petteri infected in CD mouse assessed as suppression of parasitaemia at 1 mg/kg/day, ip administered from day 0 to day 3 and measured on day 4 by Giemsa staining relative to control
Antiplasmodial activity Plasmodium vinckei petteri infected in CD mouse assessed as suppression of parasitaemia at 5 mg/kg/day, ip administered from day 0 to day 3 and measured on day 4 by Giemsa staining relative to control
Antiplasmodial activity Plasmodium vinckei petteri infected in CD mouse assessed as suppression of parasitaemia at 2.5 mg/kg/day, ip administered from day 0 to day 3 and measured on day 4 by Giemsa staining relative to control
Antiplasmodial activity Plasmodium vinckei petteri infected in ip dosed CD mouse assessed as suppression of parasitaemia administered from day 0 to day 3 and measured on day 4 by Giemsa staining
Antiplasmodial activity Plasmodium vinckei petteri infected in CD mouse assessed as survival of infected mouse at 10 mg/kg/day, ip administered from day 0 to day 3 and measured on day 4 (Rvb = 9.5 days)
Antiplasmodial activity Plasmodium vinckei petteri infected in CD mouse assessed as survival of infected mouse at 1 mg/kg/day, ip administered from day 0 to day 3 and measured on day 4 (Rvb = 9.5 days)
Antiplasmodial activity Plasmodium vinckei petteri infected in CD mouse assessed as survival of infected mouse at 5 mg/kg/day, ip administered from day 0 to day 3 and measured on day 4 (Rvb = 9.5 days)
Antiplasmodial activity Plasmodium vinckei petteri infected in CD mouse assessed as survival of infected mouse at 2.5 mg/kg/day, ip administered from day 0 to day 3 and measured on day 4 (Rvb = 9.5 days)
Antimalarial activity against Plasmodium vinckei petteri 279BY infected in ip dosed Swiss mouse assessed as reduction in parasitemia administered QD for 4 days measured on day 5
Antimalarial activity against Plasmodium vinckei petteri 279BY infected in po dosed Swiss mouse assessed as reduction in parasitemia administered QD for 4 days measured on day 5
Ratio of ED50 for Plasmodium vinckei petteri 279BY infected in ip dosed Swiss mouse to ED50 for Plasmodium venckei petteri 279BY infected in po dosed Swiss mouse