Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through percutaneous route in BALB/c mouse assessed as protection against virus-induced systemic disease symptoms at 100 mg/kg, po qd measured after 6 days postinfection
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through dermal scarification route in BALB/c mouse assessed as protection against virus-induced systemic disease symptoms at 100 mg/kg, po qd measured after 9 days postinfection
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through intravenous route in BALB/c mouse assessed as protection against virus-induced systemic disease symptoms at 100 mg/kg, po qd measured after 9 days postinfection
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through subcutaneous route in BALB/c mouse assessed as protection against virus-induced systemic disease symptoms at 100 mg/kg, po qd measured after 9 days postinfection
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through intraperitoneal route in BALB/c mouse assessed as protection against virus-induced systemic disease symptoms at 100 mg/kg, po qd measured after 9 days postinfection
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through percutaneous route in BALB/c mouse assessed as protection against virus-induced satellite lesion formation on tails at 100 mg/kg, po qd measured after 6 days postinfection
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through percutaneous route in BALB/c mouse assessed as protection against virus-induced conjunctivitis in mouse eyes at 100 mg/kg, po qd measured after 6 days postinfection
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through dermal scarification route in BALB/c mouse assessed as protection against virus-induced satellite lesion formation on tails at 100 mg/kg, po qd measured after 6 days postinfection
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through dermal scarification route in BALB/c mouse assessed as protection against virus-induced conjunctivitis in mouse eyes at 100 mg/kg, po qd measured after 6 days postinfection
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through intravenous route in BALB/c mouse assessed as protection against virus-induced satellite lesion formation on tails at 100 mg/kg, po qd measured after 6 days postinfection
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through intravenous route in BALB/c mouse assessed as protection against virus-induced conjunctivitis in mouse eyes at 100 mg/kg, po qd measured after 6 days postinfection
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through subcutaneous route in BALB/c mouse assessed as protection against virus-induced satellite lesion formation on tails at 100 mg/kg, po qd measured after 6 days postinfection
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through subcutaneous route in BALB/c mouse assessed as protection against virus-induced conjunctivitis in mouse eyes at 100 mg/kg, po qd measured after 6 days postinfection
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through intraperitoneal route in BALB/c mouse assessed as protection against virus-induced satellite lesion formation on tails at 100 mg/kg, po qd measured after 6 days postinfection
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through intraperitoneal route in BALB/c mouse assessed as protection against virus-induced conjunctivitis in mouse eyes at 100 mg/kg, po qd measured after 6 days postinfection
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through percutaneous route in BALB/c mouse assessed as reduction of viral load in lungs at 100 mg/kg, po qd measured after 3 days postinfection by RT-PCR analysis relative to control
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through percutaneous route in BALB/c mouse assessed as reduction of viral load in lungs at 100 mg/kg, po qd measured after 5 days postinfection by RT-PCR analysis relative to control
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through percutaneous route in BALB/c mouse assessed as reduction of viral load in blood at 100 mg/kg, po qd measured after 3 days postinfection by RT-PCR analysis relative to control
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through percutaneous route in BALB/c mouse assessed as reduction of viral load in spleen at 100 mg/kg, po qd measured after 3 days postinfection by RT-PCR analysis relative to control
Antiviral activity against Vaccinia virus WR ATCC VR-1354 infected through percutaneous route in BALB/c mouse assessed as reduction of viral load in liver at 100 mg/kg, po qd measured after 3 days postinfection by RT-PCR analysis relative to control