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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA3531070 ADME Drug level in beagle dog liver assessed as free base level at 40 mg/kg/day, po administered as repeat dose measured after 24 hrs on day 14 Canis lupus familiaris 1 ALA3526147 organism-based format Scientific Literature 2. ALA3531071 ADME Drug level in beagle dog liver assessed as free base level at 40 mg/kg/day, po administered as repeat dose measured after 24 hrs on day 34 Canis lupus familiaris 1 ALA3526147 organism-based format Scientific Literature 3. ALA3530044 ADME Drug metabolism in dog liver slices assessed as (2R,2'R)-2,2'-(diimidazo[4,5-b:4',5'-e]pyridine-1,7-diyl)bis(2-(4-fluorophenyl)-1-(pyrrolidin-1-yl)propan-1-one) formation at 50 uM after 24 hrs Canis lupus familiaris 1 ALA3525909 tissue-based format Scientific Literature 4. ALA3610482 ADME Prodrug conversion in dog liver S9 fractions assessed as formation of 1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl)pyrimidin-5-yl]-7-[(2R)-tetrahydrofuran-2-yl]-1H-benzimidazol-2-yl]urea by Michaelis-Menten plot analysis Canis lupus familiaris 1 ALA3608279 subcellular format Scientific Literature 5. ALA3830684 ADME Cmax in dog liver at 50 mg/kg, po Canis lupus familiaris 1 ALA3826882 organism-based format Scientific Literature 6. ALA3830685 ADME Tmax in dog liver at 50 mg/kg, po Canis lupus familiaris 1 ALA3826882 organism-based format Scientific Literature 7. ALA3830686 ADME AUC (0 to last) in dog liver at 50 mg/kg, po Canis lupus familiaris 1 ALA3826882 organism-based format Scientific Literature 8. ALA3830687 ADME Tlast in dog liver at 50 mg/kg, po Canis lupus familiaris 1 ALA3826882 organism-based format Scientific Literature 9. ALA3830688 ADME Half life in dog liver at 50 mg/kg, po Canis lupus familiaris 1 ALA3826882 organism-based format Scientific Literature 10. ALA3830689 ADME AUC (0 to infinity) in dog liver at 50 mg/kg, po Canis lupus familiaris 1 ALA3826882 organism-based format Scientific Literature 11. ALA3830798 ADME Cmax in dog liver assessed as 2'-deoxy-2'-spirooxetane uridine triphosphate at 50 mg/kg, po Canis lupus familiaris 1 ALA3826882 organism-based format Scientific Literature 12. ALA3830799 ADME Tmax in dog liver assessed as 2'-deoxy-2'-spirooxetane uridine triphosphate at 50 mg/kg, po Canis lupus familiaris 1 ALA3826882 organism-based format Scientific Literature 13. ALA3830800 ADME AUC (0 to last) in dog liver assessed as 2'-deoxy-2'-spirooxetane uridine triphosphate at 50 mg/kg, po Canis lupus familiaris 1 ALA3826882 organism-based format Scientific Literature 14. ALA3830801 ADME Tlast in dog liver assessed as 2'-deoxy-2'-spirooxetane uridine triphosphate at 50 mg/kg, po Canis lupus familiaris 1 ALA3826882 organism-based format Scientific Literature 15. ALA3830802 ADME Half life in dog liver assessed as 2'-deoxy-2'-spirooxetane uridine triphosphate at 50 mg/kg, po Canis lupus familiaris 1 ALA3826882 organism-based format Scientific Literature 16. ALA3830803 ADME AUC (0 to infinity) in dog liver assessed as 2'-deoxy-2'-spirooxetane uridine triphosphate at 50 mg/kg, po Canis lupus familiaris 1 ALA3826882 organism-based format Scientific Literature 17. ALA900226 ADME Metabolic stability in dog liver microsomes Canis lupus familiaris 1 ALA1138245 microsome format Scientific Literature 18. ALA901396 ADME Metabolic stability in dog liver microsomes assessed as systemic clearance Canis lupus familiaris 1 ALA1138325 microsome format Scientific Literature 19. ALA944816 ADME Intrinsic clearance in dog liver microsome at 1 uM Canis lupus familiaris 1 ALA1140731 microsome format Scientific Literature 20. ALA1064423 ADME Drug level in Beagle dog liver at 5 mg/kg, po after 2 hrs by LC/MS analysis Canis lupus familiaris 1 ALA1157609 organism-based format Scientific Literature