| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA964516 | F | Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp method | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 2. | ALA964517 | B | Activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production at 300 uM by two electrode voltage clamp method relative to GABA | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 3. | ALA964518 | B | Activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production at 600 uM by two electrode voltage clamp method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA964522 | B | Intrinsic activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as maximum whole cell current production by two electrode voltage clamp method relative to GABA | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA2167243 | B | Inhibition of human GABAB1A receptor at 10 uM by radioligand displacement assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA2395266 | B | Displacement of [3H]CGP54626 from human recombinant GABAB1A receptor expressed in CHO cells after 3 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA2396074 | B | Displacement of [3H]CGP54626 from human recombinant GABAB1A receptor expressed in CHO cells at 10 uM after 3 hrs relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA2396431 | B | Inhibition of human GABAB1A receptor at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA2446039 | B | Displacement of [3H]-CGP-54626 from human recombinant GABAB1A receptor expressed in CHO cells at 10 uM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3381788 | B | Displacement of [3H]CGP-54626 from human GABA B1A receptor at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA3371343 | B | Inhibition of human GABAB1A receptor at 3 uM by radioligand binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA3766813 | B | Inhibition of GABAB1A receptor (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA4029944 | B | Positive allosteric modulation at human GABA-B 1b expressed in CHO cells co-expressing rat GABA-B2 assessed as potentiation of GABA-induced inhibition of 7beta forskolin-stimulated cyclic AMP formation at 10 uM after 2 hrs in presence of 0.3 uM GABA relative to 100 uM GABA alone | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4029945 | B | Positive allosteric modulation at human GABA-B 1b expressed in CHO cells co-expressing rat GABA-B2 assessed as potentiation of GABA-induced inhibition of 7beta forskolin-stimulated cyclic AMP formation after 2 hrs in presence of 0.3 uM GABA relative to 100 uM GABA alone | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4029946 | B | Positive allosteric modulation at human GABA-B1 expressed in CHO-K1 cell membranes co-expressing rat GABA-B2 assessed as potentiation of GABA-induced reduction in [3H]-CGP62349 binding to GABA-B1 receptor at 0.3 uM measured after 20 mins in presence of 0.3 uM GABA by scintillation counting method relative to 100 uM GABA alone | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4120202 | B | Binding affinity to GABA-B1b (unknown origin) at 10 uM relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 17. | ALA4134093 | B | Inhibition of human GABA-B1A receptor at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA4140862 | B | Displacement of [3H] CGP-54626 from recombinant human GABAB isoform 1a receptor expressed in CHOK1 cell membranes at 10 uM after 180 mins by scintillation counting method relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4184474 | B | Displacement of [3H] CGP-54626 from recombinant human GABAB isoform 1a receptor expressed in CHOK1 cell membranes at 10 uM after 180 mins by scintillation counting method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4186455 | B | Displacement of [3H]CGP 54626 from human recombinant GABAB isoform 1b receptor expressed in CHO cells at 10 uM by radioligand binding assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature |
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