# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1099978 | F | Antispasmodic activity in mouse distal ileum assessed as inhibition of acetylcholine-induced contractions after 20 mins | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
2. | ALA1099979 | F | Antispasmodic activity in mouse distal ileum assessed as inhibition of acetylcholine-induced contractions at 100 ug/ml after 20 mins | Mus musculus | 11 | tissue-based format | Scientific Literature | ||
3. | ALA1839149 | F | Induction of 5-HT release from ddY mouse ileum assessed as remaining 5-HT per gram of tissue at 100 mg/kg after 20 mins by HPLC (RVb = 68.8 +/- 12.4 ng/g tissue) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
4. | ALA1839153 | F | Induction of 5-HT release from ddY mouse ileum assessed as remaining 5-HT per mg of protein at 1000 mg/kg after 20 mins by HPLC (RVb = 0.861 +/- 0.164 ng/mg protein) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
5. | ALA1839154 | F | Induction of 5-HT release from ddY mouse ileum assessed as remaining 5-HT per mg of protein at 100 mg/kg after 20 mins by HPLC (RVb = 0.861 +/- 0.164 ng/mg protein) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
6. | ALA1839155 | F | Induction of 5-HT release from ddY mouse ileum assessed per gram of tissue at 1000 mg/kg after 20 mins by HPLC (RVb = 11.2 +/- 1.3 ng/g tissue) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
7. | ALA1839156 | F | Induction of 5-HT release from ddY mouse ileum assessed per gram of tissue at 100 mg/kg after 20 mins by HPLC (RVb = 11.2 +/- 1.3 ng/g tissue) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
8. | ALA1840212 | F | Induction of 5-HT release from ddY mouse ileum assessed as remaining 5-HT per gram of tissue at 1000 mg/kg after 20 mins by HPLC (RVb = 68.8 +/- 12.4 ng/g tissue) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
9. | ALA2410587 | A | Biodistribution in mouse ileum at 3 mg/kg, po at 25 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
10. | ALA2410588 | A | Biodistribution in mouse ileum at 3 mg/kg, po at 5 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
11. | ALA2410589 | A | Biodistribution in mouse ileum at 3 mg/kg, po at 2 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
12. | ALA3537123 | A | Effective permeability of the compound in PepT1 knockout mouse ileum at 100 uM by HPLC analysis relative to wild type mouse | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
13. | ALA3538516 | A | Drug degradation in mouse ileum at 100 uM by chromatographic analysis | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
14. | ALA4044652 | A | Drug uptake in C57 mouse ileum at 10 mg/kg, po after 1 hr by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
15. | ALA4044653 | A | Drug uptake in C57 mouse ileum at 10 mg/kg, po after 2 hrs by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
16. | ALA4044654 | A | Drug uptake in C57 mouse ileum at 10 mg/kg, po after 5 hrs by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
17. | ALA4051969 | A | Drug uptake in C57BL6 mouse ileum at 20 mg/kg, po after 8 hrs by LC-MS/MS | Mus musculus | 1 | organism-based format | Scientific Literature | ||
18. | ALA4056028 | A | Drug accumulation in C57BL/6 mouse ileum at 100 mg/kg, ig for 5 days by LC-MS/MS method | Mus musculus | 2 | organism-based format | Scientific Literature |