# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1099978 | Functional | Antispasmodic activity in mouse distal ileum assessed as inhibition of acetylcholine-induced contractions after 20 mins | Mus musculus | 1 | ALA1154208 | tissue-based format | Scientific Literature | |
2. | ALA1099979 | Functional | Antispasmodic activity in mouse distal ileum assessed as inhibition of acetylcholine-induced contractions at 100 ug/ml after 20 mins | Mus musculus | 11 | ALA1154208 | tissue-based format | Scientific Literature | |
3. | ALA1839149 | Functional | Induction of 5-HT release from ddY mouse ileum assessed as remaining 5-HT per gram of tissue at 100 mg/kg after 20 mins by HPLC (RVb = 68.8 +/- 12.4 ng/g tissue) | Mus musculus | 1 | ALA1833879 | organism-based format | Scientific Literature | |
4. | ALA1839153 | Functional | Induction of 5-HT release from ddY mouse ileum assessed as remaining 5-HT per mg of protein at 1000 mg/kg after 20 mins by HPLC (RVb = 0.861 +/- 0.164 ng/mg protein) | Mus musculus | 1 | ALA1833879 | organism-based format | Scientific Literature | |
5. | ALA1839154 | Functional | Induction of 5-HT release from ddY mouse ileum assessed as remaining 5-HT per mg of protein at 100 mg/kg after 20 mins by HPLC (RVb = 0.861 +/- 0.164 ng/mg protein) | Mus musculus | 1 | ALA1833879 | organism-based format | Scientific Literature | |
6. | ALA1839155 | Functional | Induction of 5-HT release from ddY mouse ileum assessed per gram of tissue at 1000 mg/kg after 20 mins by HPLC (RVb = 11.2 +/- 1.3 ng/g tissue) | Mus musculus | 1 | ALA1833879 | organism-based format | Scientific Literature | |
7. | ALA1839156 | Functional | Induction of 5-HT release from ddY mouse ileum assessed per gram of tissue at 100 mg/kg after 20 mins by HPLC (RVb = 11.2 +/- 1.3 ng/g tissue) | Mus musculus | 1 | ALA1833879 | organism-based format | Scientific Literature | |
8. | ALA1840212 | Functional | Induction of 5-HT release from ddY mouse ileum assessed as remaining 5-HT per gram of tissue at 1000 mg/kg after 20 mins by HPLC (RVb = 68.8 +/- 12.4 ng/g tissue) | Mus musculus | 1 | ALA1833879 | organism-based format | Scientific Literature | |
9. | ALA2410587 | ADME | Biodistribution in mouse ileum at 3 mg/kg, po at 25 hrs | Mus musculus | 1 | ALA2407079 | organism-based format | Scientific Literature | |
10. | ALA2410588 | ADME | Biodistribution in mouse ileum at 3 mg/kg, po at 5 hrs | Mus musculus | 1 | ALA2407079 | organism-based format | Scientific Literature | |
11. | ALA2410589 | ADME | Biodistribution in mouse ileum at 3 mg/kg, po at 2 hrs | Mus musculus | 1 | ALA2407079 | organism-based format | Scientific Literature | |
12. | ALA3537123 | ADME | Effective permeability of the compound in PepT1 knockout mouse ileum at 100 uM by HPLC analysis relative to wild type mouse | Mus musculus | 1 | ALA3526020 | tissue-based format | Scientific Literature | |
13. | ALA3538516 | ADME | Drug degradation in mouse ileum at 100 uM by chromatographic analysis | Mus musculus | 1 | ALA3526020 | tissue-based format | Scientific Literature | |
14. | ALA4044652 | ADME | Drug uptake in C57 mouse ileum at 10 mg/kg, po after 1 hr by LC-MS/MS analysis | Mus musculus | 1 | ALA4043118 | organism-based format | Scientific Literature | |
15. | ALA4044653 | ADME | Drug uptake in C57 mouse ileum at 10 mg/kg, po after 2 hrs by LC-MS/MS analysis | Mus musculus | 1 | ALA4043118 | organism-based format | Scientific Literature | |
16. | ALA4044654 | ADME | Drug uptake in C57 mouse ileum at 10 mg/kg, po after 5 hrs by LC-MS/MS analysis | Mus musculus | 1 | ALA4043118 | organism-based format | Scientific Literature | |
17. | ALA4051969 | ADME | Drug uptake in C57BL6 mouse ileum at 20 mg/kg, po after 8 hrs by LC-MS/MS | Mus musculus | 1 | ALA4049444 | organism-based format | Scientific Literature | |
18. | ALA4056028 | ADME | Drug accumulation in C57BL/6 mouse ileum at 100 mg/kg, ig for 5 days by LC-MS/MS method | Mus musculus | 2 | ALA4052684 | organism-based format | Scientific Literature |