Biodistribution in 15 mg/kg unlabeled 6,7-dimethoxy-2-(3-(5-methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)propyl)-1,2,3,4-tetrahydroisoquinoline pretreated Wistar rat ileum at 13+/-2 MBq, iv after 80 mins
Efflux Rattus norvegicus (rat)io of apparent permeability from basal to apical side over apical to basal side of Sprague-Dawley Rattus norvegicus (rat) ileum sac at 1 mg/ml by HPLC method in presence of 250 uM P-gp/MRP2 inhibitor, verampil
Efflux Rattus norvegicus (rat)io of apparent permeability from basal to apical side over apical to basal side of Sprague-Dawley Rattus norvegicus (rat) jileum sac at 500 ug/ml by HPLC method in presence of 250 uM P-gp/MRP2 inhibitor, verampil
Apparent permeability across basal to apical side of Sprague-Dawley Rattus norvegicus (rat) everted ileum sac at 1 mg/ml by HPLC method in presence of 250 uM P-gp/MRP2 inhibitor, verampil
Apparent permeability across basal to apical side of Sprague-Dawley Rattus norvegicus (rat) everted ileum sac at 500 ug/ml by HPLC method in presence of 250 uM P-gp/MRP2 inhibitor, verampil