# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3595107 | Functional | Vasodilating activity in potassium chloride-mediated precontracted guinea pig aorta compound treated every 45 mins by chart recorder analysis | Cavia porcellus | 29 | ALA3593226 | tissue-based format | Scientific Literature | |
2. | ALA3595116 | Functional | Vasodilating activity in potassium chloride-mediated precontracted guinea pig aorta at EC50 compound treated every 45 mins by chart recorder analysis in presence of 30 uM KATP channel inhibitor glibenclamide | Cavia porcellus | 2 | ALA3593226 | tissue-based format | Scientific Literature | |
3. | ALA3595117 | Functional | Vasodilating activity in potassium chloride-mediated precontracted guinea pig aorta at EC50 compound incubated in sealed tube filled with distilled water at room temperature for 24 hrs prior to testing by chart recorder analysis | Cavia porcellus | 2 | ALA3593226 | tissue-based format | Scientific Literature | |
4. | ALA3595118 | Functional | Vasodilating activity in potassium chloride-mediated precontracted guinea pig aorta at EC50 compound treated every 45 mins by chart recorder analysis in presence of 100 uM KATP channel inhibitor glibenclamide | Cavia porcellus | 2 | ALA3593226 | tissue-based format | Scientific Literature | |
5. | ALA3595119 | Functional | Vasodilating activity in potassium chloride-mediated precontracted guinea pig aorta at EC50 compound treated every 45 mins by chart recorder analysis in presence of 100 uM eNOS inhibitor nitro-L-arginine | Cavia porcellus | 1 | ALA3593226 | tissue-based format | Scientific Literature | |
6. | ALA3820770 | Functional | Vasorelaxant activity in potassium depolarized guinea pig aorta assessed as relaxation of calcium-induced contraction at 10'-6 M after 30 mins | Cavia porcellus | 1 | ALA3817843 | tissue-based format | Scientific Literature | |
7. | ALA3821366 | Functional | Vasorelaxant activity in potassium depolarized guinea pig aorta assessed as relaxation of calcium-induced contraction | Cavia porcellus | 3 | ALA3817843 | tissue-based format | Scientific Literature | |
8. | ALA3821367 | Functional | Inhibition of diltiazem-induced vasorelaxant activity in potassium depolarized guinea pig aorta assessed as relaxation of calcium-induced contraction at 10'-6 M preincubated for 30 mins followed by diltiazem addition | Cavia porcellus | 1 | ALA3817843 | tissue-based format | Scientific Literature | |
9. | ALA3821368 | Functional | Inhibition of verapamil-induced vasorelaxant activity in potassium depolarized guinea pig aorta assessed as relaxation of calcium-induced contraction at 10'-6 M preincubated for 30 mins followed by verapamil addition | Cavia porcellus | 1 | ALA3817843 | tissue-based format | Scientific Literature | |
10. | ALA3821369 | Functional | Inhibition of nifedipine-induced vasorelaxant activity in potassium depolarized guinea pig aorta assessed as relaxation of calcium-induced contraction at 10'-6 M preincubated for 30 mins followed by nifedipine addition | Cavia porcellus | 1 | ALA3817843 | tissue-based format | Scientific Literature | |
11. | ALA3821510 | Functional | Vasorelaxant activity in potassium depolarized guinea pig aorta assessed as inhibition of calcium-induced contraction at 10'-6 M | Cavia porcellus | 2 | ALA3817843 | tissue-based format | Scientific Literature | |
12. | ALA3821511 | Functional | Vasorelaxant activity in potassium depolarized guinea pig aorta assessed as inhibition of calcium-induced contraction at 10'-8 M preincubated for 30 mins followed by 0.5 uM nifedipine addition | Cavia porcellus | 1 | ALA3817843 | tissue-based format | Scientific Literature | |
13. | ALA3821512 | Functional | Vasorelaxant activity in potassium depolarized guinea pig aorta assessed as inhibition of calcium-induced contraction at 10'-6 M preincubated for 30 mins followed by 0.5 uM nifedipine addition | Cavia porcellus | 1 | ALA3817843 | tissue-based format | Scientific Literature | |
14. | ALA3821513 | Functional | Vasorelaxant activity in potassium depolarized guinea pig aorta assessed as inhibition of calcium-induced contraction at 10'-8 M preincubated for 30 mins followed by 5 uM verapamil addition | Cavia porcellus | 1 | ALA3817843 | tissue-based format | Scientific Literature | |
15. | ALA3821514 | Functional | Vasorelaxant activity in potassium depolarized guinea pig aorta assessed as inhibition of calcium-induced contraction at 10'-6 M preincubated for 30 mins followed by 10'-5 M verapamil addition | Cavia porcellus | 1 | ALA3817843 | tissue-based format | Scientific Literature | |
16. | ALA3821515 | Functional | Vasorelaxant activity in potassium depolarized guinea pig aorta assessed as inhibition of calcium-induced contraction at 10'-4 M | Cavia porcellus | 1 | ALA3817843 | tissue-based format | Scientific Literature | |
17. | ALA3821516 | Functional | Vasorelaxant activity in potassium depolarized guinea pig aorta assessed as inhibition of calcium-induced contraction at 10'-8 M preincubated for 30 mins followed by 50 uM diltiazem addition | Cavia porcellus | 1 | ALA3817843 | tissue-based format | Scientific Literature | |
18. | ALA3821517 | Functional | Vasorelaxant activity in potassium depolarized guinea pig aorta assessed as inhibition of calcium-induced contraction at 10'-6 M preincubated for 30 mins followed by 50 uM diltiazem addition | Cavia porcellus | 1 | ALA3817843 | tissue-based format | Scientific Literature | |
19. | ALA3821518 | Functional | Vasorelaxant activity in potassium depolarized guinea pig aorta assessed as IC50 for diltiazem at 10'-8 M preincubated for 30 mins followed diltiazem addition | Cavia porcellus | 1 | ALA3817843 | tissue-based format | Scientific Literature | |
20. | ALA3821530 | Functional | Vasorelaxant activity in potassium depolarized guinea pig aorta assessed as inhibition of calcium-induced contraction at 10'-4 M after 30 mins | Cavia porcellus | 22 | ALA3817843 | tissue-based format | Scientific Literature |