| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1036409 | B | Inhibition of human recombinant DNMT3b2 expressed in baculovirus infected high five insect cells | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 2. | ALA1036410 | B | Inhibition of human recombinant DNMT3b2 expressed in baculovirus infected high five insect cells at 45 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA1036411 | B | Ratio of SAH IC50 to compound IC50 for human recombinant DNMT3b2 | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 4. | ALA1036445 | B | Inhibition of human recombinant DNMT3b2 | Homo sapiens | 21 | single protein format | Scientific Literature | ||
| 5. | ALA1036447 | B | Inhibition of human recombinant DNMT3b2 at 45 uM | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 6. | ALA1072865 | B | Inhibition of human recombinant DNMT3B expressed in baculovirus-insect cell system at 100 uM by scintillation counting | Homo sapiens | 18 | assay format | Scientific Literature | ||
| 7. | ALA1072867 | B | Inhibition of human recombinant DNMT3B expressed in baculovirus-insect cell system by scintillation counting | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 8. | ALA1070344 | B | Binding affinity to DNMT3b in human PC3 cells cytoplasm at 5 uM after 1 hr by antibody staining | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA1070345 | B | Binding affinity to DNMT3b in human PC3 cells cytoplasm at 5 uM after 6 hrs by antibody staining | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3389595 | B | Inhibition of DNMT3B (unknown origin) incubated for 15 mins before addition of [3H]-SAM and poly(dI-dC).poly(dI-dC) by liquid scintillation counting based radioactive methylation assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA3418014 | B | Inhibition of His6-tagged human recombinant DNMT3b expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biotinylated 45-bp unmethylated or hemimethylated oligonucleotide substrates and [3H]-AdoMet by liquid scintillation counting method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA3578934 | B | Inhibition of human full length DNMT3B expressed in Sf9 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4391129 | B | Inhibition of DNMT3B (unknown origin) at 100 uM using cytosine-rich DNA substrate by ELISA relative to untreated control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA4401534 | B | Inhibition of N-terminal GST-tagged recombinant full length human DNMT3b (2 to 853 residues) using bacteriophage lambda DNA as substrate preincubated for 20 mins followed by [3H]-SAM and measured after 60 mins by scintillation counting | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA4606694 | B | Inhibition of human DNMT3B using [3H]-SAM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA4606697 | B | Inhibition of human recombinant DNMT3B expressed in baculovirus infected insect cells using CpG site containing internally quenched hairpin oligonucleotide DNA substrate and SAM incubated for 30 mins by kinetic fluorogenic assay | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 17. | ALA4606699 | B | Inhibition of human recombinant DNMT3B expressed in baculovirus infected insect cells by DRONE assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA4682603 | B | Inhibition of human DNMT3B expressed in Escherichia coli Rosetta-gamiTM 2(DE3) pLysS competent cells using biotinylated 6-FAM double strand DNA comprising unique CpG site [3H]-SAM incubated for 1 hrs by fluorescence based assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 19. | ALA4682606 | B | Inhibition of human DNMT3B in human KG-1 cells expressing cmv-firefly luciferase assessed as increase in luminescence upto 10 uM incubated for 24 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 20. | ALA4682607 | B | Inhibition of human DNMT3B expressed in Escherichia coli Rosetta-gamiTM 2(DE3) pLysS competent cells using biotinylated 6-FAM double strand DNA comprising unique CpG site [3H]-SAM at 1 uM incubated for 1 hrs by fluorescence based assay | Homo sapiens | 3 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!