| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1918491 | F | Agonist activity at Ah receptor in genetically engineered mouse cells expressing firefly luciferase gene by CALUX transactivational assay | Mus musculus | 5 | assay format | Scientific Literature | ||
| 2. | ALA1052629 | B | Induction of mouse AhR LBD transcriptional activity in mouse hepa1 cells transfected with AhR response element co expressed with XRE after 6 hrs by luciferase reporter gene assay relative to control | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 3. | ALA1052630 | B | Induction of mouse AhR LBD transcriptional activity in mouse hepa1 cells transfected with AhR response element co expressed with XRE at 1 nM after 6 hrs by luciferase reporter gene assay in presence of 6-hydroxy-7-methoxyflavone | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA1052631 | B | Induction of mouse AhR LBD transcriptional activity in mouse hepa1 cells transfected with AhR response element co expressed with XRE at 300 pM after 6 hrs by luciferase reporter gene assay in presence of 6-hydroxy-7-methoxyflavone | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA1052632 | B | Induction of mouse AhR LBD transcriptional activity in mouse hepa1 cells transfected with AhR response element co expressed with XRE at 100 pM after 6 hrs by luciferase reporter gene assay in presence of 6-hydroxy-7-methoxyflavone | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA1052633 | B | Induction of mouse AhR LBD transcriptional activity in mouse hepa1 cells transfected with AhR response element co expressed with XRE at 20 uM after 6 hrs by luciferase reporter gene assay in presence of 6-hydroxy-7-methoxyflavone | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA1052634 | B | Effect on AhR-mediated CYP1A1 activation in mouse Hepa1c1c12 cells at 20 uM after 18 hrs by Western blot analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA1052635 | B | Effect on AhR-mediated NAPDH quinine reductase activation in mouse Hepa1c1c12 cells at 20 uM after 18 hrs by Western blot analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA1052636 | B | Induction of nuclear translocation of AhR from cytosol in mouse Hepa1 cells at 20 uM after 60 mins using DAPI staining by microscopic analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA1175423 | B | Induction of Ah receptor in mouse Hepa-1c1c7 cells assessed as induction of CYP1A1 activity at 10 uM after 48 hrs by EROD assay relative to control | Mus musculus | 15 | cell-based format | Scientific Literature | ||
| 11. | ALA1175424 | B | Induction of Ah receptor in mouse Hepa-1c1c7 cells assessed as induction of CYP1A1 activity at 25 uM after 48 hrs by EROD assay relative to control | Mus musculus | 10 | cell-based format | Scientific Literature | ||
| 12. | ALA1175425 | B | Induction of Ah receptor in mouse Hepa-1c1c7 cells assessed as induction of CYP1A1 activity at 5 uM after 48 hrs by EROD assay relative to control | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA1175426 | B | Induction of Ah receptor in mouse Hepa-1c1c7 cells assessed as induction of CYP1A1 activity at 1 uM after 48 hrs by EROD assay relative to control | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA3269632 | B | Agonist activity at AHR in mouse HC11 cells assessed as upregulation of Cyp1a1 gene expression at 10 uM after 48 hrs by RT-PCR analysis relative to control | Mus musculus | 25 | cell-based format | Scientific Literature | ||
| 15. | ALA3269633 | B | Agonist activity at AHR in FVB/N mouse primary mammary epithelial cells assessed as blockade of mammary branching morphogenesis after 144 hrs by microscopic analysis in presence of FGF2 | Mus musculus | 5 | cell-based format | Scientific Literature | ||
| 16. | ALA3269634 | B | Agonist activity at AHR in FVB/N mouse primary mammary epithelial cells assessed as upregulation of desmoglein-3 protein level at 10 nM after 144 hrs by Western blot analysis in presence of FGF2 | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3269635 | B | Agonist activity at AHR in FVB/N mouse primary mammary epithelial cells assessed as upregulation of desmoglein-3 protein level at 10 uM after 144 hrs by Western blot analysis in presence of FGF2 | Mus musculus | 6 | cell-based format | Scientific Literature | ||
| 18. | ALA4324436 | B | Displacement of 2-azido-3-[125I]7,8-dibromodibenzo-pdioxin from C57BL/6J mouse liver AhR | Mus musculus | 1 | assay format | Scientific Literature | ||
| 19. | ALA4324437 | B | Displacement of 2-azido-3-[125I]7,8-dibromodibenzo-pdioxin from C57BL/6J mouse liver AhR incubated for 20 mins by gamma counting based autoradiography | Mus musculus | 2 | assay format | Scientific Literature | ||
| 20. | ALA4324441 | B | Displacement of [3H]TCDD from mouse AhR | Mus musculus | 1 | single protein format | Scientific Literature |
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