# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1057938 | B | Inhibition of human influenza A/Memphis/1/71(H3N2) sialidase by fluorescence spectrophotometry | Influenza A virus (A/Memphis/1/1971(H3N2)) | 14 | ALA1152425 | single protein format | Scientific Literature | |
2. | ALA4120976 | B | Inhibition of Influenza A virus (A/Fukui/45/04(H3N2)) neuraminidase activity using 4-MUNANA as substrate measured every min for 60 mins by fluorescence assay | Influenza A virus (A/Fukui/45/2004(H3N2)) | 6 | ALA4118102 | single protein format | Scientific Literature | |
3. | ALA4120977 | B | Inhibition of Influenza A virus (A/Fukui/45/04(H3N2)) neuraminidase activity using 4-MUNANA as substrate preincubated for 60 mins followed by substrate addition measured every min for 60 mins by fluorescence assay | Influenza A virus (A/Fukui/45/2004(H3N2)) | 6 | ALA4118102 | single protein format | Scientific Literature | |
4. | ALA4120992 | B | Inhibition of Influenza A virus (A/Fukui/45/04(H3N2)) neuraminidase activity using 4-MUNANA as substrate assessed as reactivation half life by measuring reaction rate to reach 50% of maximum rate of uninhibited control after removal of inhibitor preincubated for 30 mins followed by compound washout and subsequent substrate addition measured after each 10 mins for 4 hrs by fluorescence assay (Rvb = 12.8 +/- 3.5 min) | Influenza A virus (A/Fukui/45/2004(H3N2)) | 6 | ALA4118102 | single protein format | Scientific Literature | |
5. | ALA4121006 | B | Ratio of IC50 for Influenza A virus (A/Fukui/45/04(H3N2)) neuraminidase measured every min for 60 mins to IC50 for Influenza A virus (A/Fukui/45/04(H3N2)) neuraminidase preincubated for 60 mins followed by substrate addition measured every min for 60 mins | Influenza A virus (A/Fukui/45/2004(H3N2)) | 6 | ALA4118102 | single protein format | Scientific Literature | |
6. | ALA4150708 | B | Inhibition of Influenza A virus (H3N2) neuraminidase activity | Influenza A virus H3N2 | 3 | ALA4145638 | single protein format | Scientific Literature | |
7. | ALA4150711 | B | Inhibition of Influenza A virus (A/Paris/908/97 (H3N2)) neuraminidase activity by fluorometric assay | Influenza A virus (A/Paris/908/97(H3N2)) | 1 | ALA4145638 | single protein format | Scientific Literature | |
8. | ALA4150713 | B | Inhibition of Influenza A virus Taiwan/3446/2002 (H3N2) neuraminidase activity using fluorogenic substrate MU-NANA pre-incubated for 30 mins before fluorogenic substrate addition and measured after 1 hr by spectrofluorometry | Influenza A virus H3N2 | 1 | ALA4145638 | single protein format | Scientific Literature | |
9. | ALA4182636 | B | Inhibition of Influenza A virus A/Memphis/1/71(H3N2) sialidase at 3.33 x 10'-4M preincubated for 15 mins followed by MUNA substrate addition measured after 15 mins by fluorescence assay relative to control | Influenza A virus (A/Memphis/1/1971(H3N2)) | 11 | ALA4177726 | single protein format | Scientific Literature | |
10. | ALA4182639 | B | Inhibition of Influenza A virus A/Memphis/1/71(H3N2) sialidase preincubated for 15 mins followed by MUNA substrate addition measured after 15 mins by fluorescence assay | Influenza A virus (A/Memphis/1/1971(H3N2)) | 1 | ALA4177726 | single protein format | Scientific Literature | |
11. | ALA4254783 | B | Inhibition of Influenza A virus (A/Brisbane/10/2007(H3N2)) recombinant neuraminidase expressed in HEK293 cells pre-incubated for 10 mins before 4-MUNANA substrate addition by fluorometry | Influenza A virus (A/Brisbane/10/2007(H3N2)) | 3 | ALA4251642 | cell-based format | Scientific Literature | |
12. | ALA4363627 | B | Inhibition of influenza A virus H3N2 clinical isolate neuraminidase at 1 nM using NA-Fluor MUNANA as substrate preincubated for 20 to 30 mins followed by substrate addition and measured for 60 mins by fluorescence assay relative to control | Influenza A virus H3N2 | 31 | ALA4359912 | single protein format | Scientific Literature | |
13. | ALA4363628 | B | Inhibition of influenza A virus H3N2 clinical isolate neuraminidase using NA-Fluor MUNANA as substrate preincubated for 20 to 30 mins followed by substrate addition and measured for 60 mins by fluorescence assay | Influenza A virus H3N2 | 3 | ALA4359912 | single protein format | Scientific Literature | |
14. | ALA4364577 | B | Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by substrate addition and measured after 40 mins by fluorescence based assay | Influenza A virus | 22 | ALA4364245 | single protein format | Scientific Literature | |
15. | ALA4403915 | B | Inhibition of Influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 preincubated for 10 mins followed by MUNANA substrate addition and measured after 40 mins by fluorescence method | Influenza A virus | 34 | ALA4402551 | single protein format | Scientific Literature | |
16. | ALA4426626 | B | Binding affinity to recombinant Influenza A virus (A/Moscow/10/99(H3N2)) Neuraminidase N2 expressed in baculovirus infected insect cells at 100 to 1000 nM measured up to 160 sec by surface plasmon resonance analysis | Influenza A virus | 1 | ALA4425127 | cell-based format | Scientific Literature |