# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3878974 | B | Inhibition of human BCR/ABL p210 fusion protein expressed in BAF3 cells assessed as growth inhibition measured after 72 hrs by CellTiter-Glo or CCK8 assay | Homo sapiens | 30 | ALA3877303 | cell-based format | Scientific Literature | |
2. | ALA3879029 | B | Inhibition of BCR/ABL p210 fusion protein autophosphorylation at Y245 in human K562 cells measured after 2 hrs by immunoblotting | Homo sapiens | 1 | ALA3877303 | cell-based format | Scientific Literature | |
3. | ALA3879030 | B | Inhibition of BCR/ABL p210 fusion protein mediated signaling pathways assessed as reduction in Stat5 phosphorylation at Y694 in human K562 cells at 0.01 to 3 uM measured after 2 hrs by immunoblotting | Homo sapiens | 1 | ALA3877303 | cell-based format | Scientific Literature | |
4. | ALA3879031 | B | Inhibition of BCR/ABL p210 fusion protein mediated signaling pathways assessed as reduction in CrkL phosphorylation at Y207 in human K562 cells at 0.01 to 3 uM measured after 2 hrs by immunoblotting | Homo sapiens | 1 | ALA3877303 | cell-based format | Scientific Literature | |
5. | ALA3879032 | B | Inhibition of BCR/ABL p210 fusion protein mediated signaling pathways assessed as reduction in ERK phosphorylation at T202/Y204 in human K562 cells at 0.01 to 3 uM measured after 2 hrs by immunoblotting | Homo sapiens | 1 | ALA3877303 | cell-based format | Scientific Literature | |
6. | ALA3879033 | B | Inhibition of BCR/ABL p210 fusion protein autophosphorylation at Y245 in human KU812 cells at 0.01 to 3 uM measured after 2 hrs by immunoblotting | Homo sapiens | 1 | ALA3877303 | cell-based format | Scientific Literature | |
7. | ALA3879034 | B | Inhibition of BCR/ABL p210 fusion protein mediated signaling pathways assessed as reduction in Stat5 phosphorylation at Y694 in human KU812 cells at 0.01 to 3 uM measured after 2 hrs by immunoblotting | Homo sapiens | 1 | ALA3877303 | cell-based format | Scientific Literature | |
8. | ALA3879035 | B | Inhibition of BCR/ABL p210 fusion protein mediated signaling pathways assessed as reduction in CrkL phosphorylation at Y207 in human KU812 cells at 0.01 to 3 uM measured after 2 hrs by immunoblotting | Homo sapiens | 1 | ALA3877303 | cell-based format | Scientific Literature | |
9. | ALA3879036 | B | Inhibition of BCR/ABL p210 fusion protein mediated signaling pathways assessed as reduction in ERK phosphorylation at T202/Y204 in human KU812 cells at 0.01 to 3 uM measured after 2 hrs by immunoblotting | Homo sapiens | 1 | ALA3877303 | cell-based format | Scientific Literature | |
10. | ALA3879037 | B | Inhibition of BCR/ABL p210 fusion protein mediated signaling pathways assessed as reduction in Stat5 phosphorylation at Y694 in human MEG01 cells at 0.01 to 3 uM measured after 2 hrs by immunoblotting | Homo sapiens | 1 | ALA3877303 | cell-based format | Scientific Literature | |
11. | ALA3879038 | B | Inhibition of BCR/ABL p210 fusion protein mediated signaling pathways assessed as reduction in CrkL phosphorylation at Y207 in human MEG01 cells at 0.01 to 3 uM measured after 2 hrs by immunoblotting | Homo sapiens | 1 | ALA3877303 | cell-based format | Scientific Literature | |
12. | ALA3879039 | B | Inhibition of BCR/ABL p210 fusion protein mediated signaling pathways assessed as reduction in ERK phosphorylation at T202/Y204 in human MEG01 cells at 0.01 to 3 uM measured after 2 hrs by immunoblotting | Homo sapiens | 1 | ALA3877303 | cell-based format | Scientific Literature | |
13. | ALA3879040 | B | Inhibition of BCR/ABL p210 fusion protein autophosphorylation at Y245 in human MEG10 cells at 0.01 to 3 uM measured after 2 hrs by immunoblotting | Homo sapiens | 1 | ALA3877303 | cell-based format | Scientific Literature |