# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA926831 | B | Inhibition of human LSD1 | Homo sapiens | 7 | ALA1144791 | single protein format | Scientific Literature | |
2. | ALA926833 | B | Ratio of Kinact to KI of human LSD1 | Homo sapiens | 7 | ALA1144791 | single protein format | Scientific Literature | |
3. | ALA1025179 | B | Inhibition of LSD1 | 1 | ALA1158462 | single protein format | Scientific Literature | ||
4. | ALA1025180 | B | Inhibition of LSD1 at 1 uM | 1 | ALA1158462 | single protein format | Scientific Literature | ||
5. | ALA1119011 | B | Reversible Inhibition of LSD1 | 1 | ALA1155444 | single protein format | Scientific Literature | ||
6. | ALA1119012 | B | Inhibition of LSD1 | 1 | ALA1155444 | single protein format | Scientific Literature | ||
7. | ALA1119013 | B | Inhibition of LSD1 in human HCT116 cells assessed as increase in cellular histone 3 dimethyllysine 4 level treated at increasing concentration after 48 hrs | Homo sapiens | 2 | ALA1155444 | cell-based format | Scientific Literature | |
8. | ALA1119014 | B | Inhibition of LSD1 in human HCT116 cells assessed as increase in cellular histone 3 methyllysine 4 level treated at increasing concentration after 48 hrs | Homo sapiens | 2 | ALA1155444 | cell-based format | Scientific Literature | |
9. | ALA1119015 | B | Inhibition of LSD1 in human HCT116 cells assessed as increase in cellular histone 3 dimethyllysine 9 level treated at increasing concentration after 48 hrs | Homo sapiens | 2 | ALA1155444 | cell-based format | Scientific Literature | |
10. | ALA1119016 | B | Inhibition of N-terminal histidine-tagged full length human recombinant LSD1 expressed in Escherichia coli BL2 (DE3) assessed as residual activity at 10 uM by chemiluminescence assay | Homo sapiens | 33 | ALA1155444 | assay format | Scientific Literature | |
11. | ALA1119017 | B | Inhibition of N-terminal histidine-tagged full length human recombinant LSD1 expressed in Escherichia coli BL2 (DE3) at 10 uM by chemiluminescence assay | Homo sapiens | 31 | ALA1155444 | assay format | Scientific Literature | |
12. | ALA1119018 | B | Inhibition of LSD1 in human Calu6 cells assessed as increase in cellular histone 3 methyllysine 4 level at 10 uM after 24 hrs by Western blot analysis | Homo sapiens | 3 | ALA1155444 | cell-based format | Scientific Literature | |
13. | ALA1119019 | B | Inhibition of LSD1 in human Calu6 cells assessed as increase in cellular histone 3 dimethyllysine 4 level at 10 uM after 24 hrs by Western blot analysis | Homo sapiens | 3 | ALA1155444 | cell-based format | Scientific Literature | |
14. | ALA1119020 | B | Inhibition of LSD1 in human Calu6 cells assessed as increase in cellular histone 3 methyllysine 4 level at 10 uM after 48 hrs by Western blot analysis | Homo sapiens | 2 | ALA1155444 | cell-based format | Scientific Literature | |
15. | ALA1119021 | B | Inhibition of LSD1 in human Calu6 cells assessed as increase in cellular histone 3 dimethyllysine 4 level at 10 uM after 48 hrs by Western blot analysis | Homo sapiens | 2 | ALA1155444 | cell-based format | Scientific Literature | |
16. | ALA1119022 | B | Inhibition of LSD1 in human HCT116 cells assessed as increase in cellular histone 3 dimethyllysine 4 level relative to control | Homo sapiens | 3 | ALA1155444 | cell-based format | Scientific Literature | |
17. | ALA1119023 | B | Inhibition of LSD1 in human Calu6 cells assessed as increase in SFRP2 gene expression after 24 hrs by quantitative PCR analysis | Homo sapiens | 1 | ALA1155444 | cell-based format | Scientific Literature | |
18. | ALA1119024 | B | Inhibition of LSD1 in human Calu6 cells assessed as increase in SFRP2 gene expression at 10 uM after 24 hrs by quantitative PCR analysis relative to control | Homo sapiens | 1 | ALA1155444 | cell-based format | Scientific Literature | |
19. | ALA1119025 | B | Inhibition of LSD1 in human Calu6 cells assessed as increase in GATA4 gene expression at 5 uM after 24 hrs by quantitative PCR analysis | Homo sapiens | 3 | ALA1155444 | cell-based format | Scientific Literature | |
20. | ALA1119026 | B | Inhibition of LSD1 in human Calu6 cells assessed as increase in GATA4 gene expression at 10 uM after 24 hrs by quantitative PCR analysis | Homo sapiens | 2 | ALA1155444 | cell-based format | Scientific Literature |