# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA618669 | F | Percent change in total cholesterol(TC) versus (T0)- at which drug intervention begins at a dose of 25 mg/kg in the chronic cholesterol-fed rabbit model | Oryctolagus cuniculus | 1 | ALA1129338 | organism-based format | Scientific Literature | |
2. | ALA618670 | F | Oral bioactivity expressed as %inhibition after 4 hours of drug administration (dose 25 mg/kg) in rabbit bioassay | Oryctolagus cuniculus | 1 | ALA1129338 | organism-based format | Scientific Literature | |
3. | ALA644122 | B | In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition by incubation with [14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits. | Oryctolagus cuniculus | 11 | ALA1127280 | assay format | Scientific Literature | |
4. | ALA644123 | B | In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) from rabbit intestinal microsomes | Oryctolagus cuniculus | 30 | ALA1131165 | assay format | Scientific Literature | |
5. | ALA644124 | F | In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase from rabbit intestinal microsomes | Oryctolagus cuniculus | 1 | ALA1131165 | assay format | Scientific Literature | |
6. | ALA644125 | B | In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol fed rabbits (IAI). | Oryctolagus cuniculus | 33 | ALA1129000 | microsome format | Scientific Literature | |
7. | ALA644126 | F | Arterial Acyl coenzyme A:cholesterol acyltransferase activity was measured in vitro in rabbit aorta after administration of 50 mg/Kg | Oryctolagus cuniculus | 1 | ALA1124972 | organism-based format | Scientific Literature | |
8. | ALA638579 | B | Compound at 5 uM concentration was tested in vitro for inhibition of Acyl-CoA: Cholesterol Acyltransferase (ACAT) in intestinal microsomes of cholesterol fed rabbits | Oryctolagus cuniculus | 1 | ALA1128046 | microsome format | Scientific Literature | |
9. | ALA638580 | B | Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rabbit adrenal. | Oryctolagus cuniculus | 2 | ALA1152120 | assay format | Scientific Literature | |
10. | ALA638581 | B | Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rabbit artery. | Oryctolagus cuniculus | 2 | ALA1152120 | assay format | Scientific Literature | |
11. | ALA638582 | B | Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rabbit intestine. | Oryctolagus cuniculus | 2 | ALA1152120 | assay format | Scientific Literature | |
12. | ALA638583 | B | Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rabbit liver. | Oryctolagus cuniculus | 2 | ALA1152120 | tissue-based format | Scientific Literature | |
13. | ALA638584 | B | Compound was tested for inhibitory activity against ACAT from rabbit adrenal gland | Oryctolagus cuniculus | 3 | ALA1131799 | tissue-based format | Scientific Literature | |
14. | ALA638585 | B | Compound was tested for inhibitory activity against ACAT from rabbit intestine | Oryctolagus cuniculus | 3 | ALA1131799 | tissue-based format | Scientific Literature | |
15. | ALA638586 | B | Compound was tested for inhibitory activity against ACAT from rabbit liver | Oryctolagus cuniculus | 3 | ALA1131799 | assay format | Scientific Literature | |
16. | ALA639298 | B | Inhibition of Acyl-CoA: Cholesterol Acyltransferase (ACAT) in intestinal microsomes of cholesterol fed rabbits | Oryctolagus cuniculus | 8 | ALA1128046 | microsome format | Scientific Literature | |
17. | ALA639299 | B | Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in intestinal microsomes isolated from cholesterol-fed rabbits | Oryctolagus cuniculus | 1 | ALA1128123 | microsome format | Scientific Literature | |
18. | ALA639300 | B | Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholesterol-fed rats was determined | Oryctolagus cuniculus | 2 | ALA1128123 | microsome format | Scientific Literature | |
19. | ALA639301 | B | Concentration required for the inhibition of rabbit arterial Acyl coenzyme A:cholesterol acyltransferase | Oryctolagus cuniculus | 1 | ALA1126412 | single protein format | Scientific Literature | |
20. | ALA639302 | B | In vitro Acyl coenzyme A:cholesterol acyltransferase inhibitory activity (IAI) was determined by measuring the incorporation of [1-14C]oleolyl-CoA into cholesterol esters by intestinal microsomes isolated from cholesterol-fed rabbits | Oryctolagus cuniculus | 77 | ALA1127594 | assay format | Scientific Literature |