| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1032991 | B | Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli TX685 assessed as NADH production by fluorescence assay in absence of 0.05% fatty acid free bovine serum albumin | Cryptosporidium parvum | 25 | assay format | Scientific Literature | ||
| 2. | ALA1032992 | B | Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli TX685 assessed as NADH production by fluorescence assay in presence of 0.05% fatty acid free bovine serum albumin | Cryptosporidium parvum | 24 | assay format | Scientific Literature | ||
| 3. | ALA1032994 | B | Ratio of IC50 for Cryptosporidium parvum recombinant IMPDH in presence of 0.05% fatty acid free bovine serum albumin to IC50 for Cryptosporidium parvum recombinant IMPDH in absence of 0.05% fatty acid free bovine serum albumin | Cryptosporidium parvum | 1 | single protein format | Scientific Literature | ||
| 4. | ALA1032995 | B | Ratio of campaign IC50 to compound IC50 for Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli TX685 in absence of 0.05% fatty acid free bovine serum albumin | Cryptosporidium parvum | 1 | assay format | Scientific Literature | ||
| 5. | ALA1032996 | B | Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli guaB assessed as NADH production by fluorescence assay | Cryptosporidium parvum | 1 | assay format | Scientific Literature | ||
| 6. | ALA1960803 | B | Inhibition of recombinant Cryptosporidium parvum IMPDH expressed in Escherichia coli assessed as NADH production preincubated for 5 mins by fluorescence assay in presence of bovine serum albumin | Cryptosporidium parvum | 38 | assay format | Scientific Literature | ||
| 7. | ALA1960806 | B | Inhibition of recombinant Cryptosporidium parvum IMPDH expressed in Escherichia coli assessed as NADH production preincubated for 5 mins by fluorescence assay | Cryptosporidium parvum | 38 | assay format | Scientific Literature | ||
| 8. | ALA2185141 | B | Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid free BSA incubated for 5 mins by fluorescence based assay | Cryptosporidium parvum | 44 | assay format | Scientific Literature | ||
| 9. | ALA2185142 | B | Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluorescence based assay | Cryptosporidium parvum | 45 | assay format | Scientific Literature | ||
| 10. | ALA2319785 | B | Mixed type inhibition of recombinant Cryptosporidium parvum IMPDH with respect to NAD+ | Cryptosporidium parvum | 2 | single protein format | Scientific Literature | ||
| 11. | ALA2319789 | B | Inhibition of recombinant Cryptosporidium parvum IMPDH assessed as production of NADH by fluorescence assay in presence of 0.05% BSA | Cryptosporidium parvum | 52 | single protein format | Scientific Literature | ||
| 12. | ALA2319790 | B | Inhibition of recombinant Cryptosporidium parvum IMPDH assessed as production of NADH by fluorescence assay | Cryptosporidium parvum | 52 | single protein format | Scientific Literature | ||
| 13. | ALA2353883 | B | Competitive inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) using NAD as substrate by Lineweaver-Burk plot analysis | Cryptosporidium parvum | 4 | assay format | Scientific Literature | ||
| 14. | ALA2353884 | B | Noncompetitive inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) using IMP as substrate by Lineweaver-Burk plot analysis | Cryptosporidium parvum | 4 | assay format | Scientific Literature | ||
| 15. | ALA2353886 | B | Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5 mins prior to substrate addition by fluorescence assay in presence of BSA | Cryptosporidium parvum | 44 | assay format | Scientific Literature | ||
| 16. | ALA2354115 | B | Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5 mins prior to substrate addition by fluorescence assay | Cryptosporidium parvum | 44 | assay format | Scientific Literature | ||
| 17. | ALA3375356 | B | Inhibition of Cryptosporidium parvum IMPDH assessed as reduction in NADH production | Cryptosporidium parvum | 21 | single protein format | Scientific Literature | ||
| 18. | ALA3362092 | B | Inhibition of Cryptosporidium IMPDH preincubated for 10 mins before substrate addition by spectrophotometry | Cryptosporidium | 17 | single protein format | Scientific Literature | ||
| 19. | ALA3362457 | B | Un-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometry | Cryptosporidium | 6 | single protein format | Scientific Literature | ||
| 20. | ALA3362470 | B | Competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometry | Cryptosporidium | 2 | single protein format | Scientific Literature |
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