| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1052434 | B | Inhibition of HIV1 NL4-3 envelope glycoprotein 120-mediated membrane fusion between virus-transfected african green monkey COS cells and human TZM-bl cells by luciferase-based cell-cell fusion assay in presence of IC9564 | Human immunodeficiency virus 1 | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA3391095 | B | Binding affinity to HIV1 His-tagged N-terminal heptad repeat of envelope glycoprotein gp41 assessed as recovery of N36 V38A mutant-drug complex after 2 hrs by LC-MS analysis | Human immunodeficiency virus 1 | 6 | assay format | Scientific Literature | ||
| 3. | ALA3391097 | B | Thermal stability of HIV1 envelope glycoprotein gp41 His-tagged N-terminal heptad repeat N36 V38A mutant-drug complex assessed as thermal unfolding transition state by measuring molar ellipticity at 4 to 90 degC by circular dichroic spectra analysis | Human immunodeficiency virus 1 | 6 | assay format | Scientific Literature | ||
| 4. | ALA3391099 | B | Binding affinity to HIV1 His-tagged N-terminal heptad repeat of envelope glycoprotein gp41 assessed as recovery of N54 V38A mutant-drug complex after 2 hrs by LC-MS analysis | Human immunodeficiency virus 1 | 6 | assay format | Scientific Literature | ||
| 5. | ALA3391101 | B | Thermal stability of HIV1 envelope glycoprotein gp41 His-tagged N-terminal heptad repeat N54 V38A mutant-drug complex assessed as thermal unfolding transition state by measuring molar ellipticity at 4 to 90 degC by circular dichroic spectra analysis | Human immunodeficiency virus 1 | 6 | assay format | Scientific Literature | ||
| 6. | ALA3602908 | B | Binding affinity to HIV1 NL4-3 gp41 N-terminal heptad repeat G36D mutant after 30 mins by CD spectroscopic analysis | Human immunodeficiency virus 1 | 3 | single protein format | Scientific Literature | ||
| 7. | ALA3602909 | B | Binding affinity to HIV1 NL4-3 gp41 N-terminal heptad repeat I37T mutant after 30 mins by CD spectroscopic analysis | Human immunodeficiency virus 1 | 3 | single protein format | Scientific Literature | ||
| 8. | ALA3602910 | B | Binding affinity to HIV1 NL4-3 gp41 N-terminal heptad repeat V38A mutant after 30 mins by CD spectroscopic analysis | Human immunodeficiency virus 1 | 3 | single protein format | Scientific Literature | ||
| 9. | ALA3602911 | B | Binding affinity to HIV1 NL4-3 gp41 N-terminal heptad repeat Q40H mutant after 30 mins by CD spectroscopic analysis | Human immunodeficiency virus 1 | 3 | single protein format | Scientific Literature | ||
| 10. | ALA3602912 | B | Binding affinity to HIV1 NL4-3 gp41 N-terminal heptad repeat N43K mutant after 30 mins by CD spectroscopic analysis | Human immunodeficiency virus 1 | 3 | single protein format | Scientific Literature | ||
| 11. | ALA3602913 | B | Binding affinity to HIV1 NL4-3 gp41 N-terminal heptad repeat I37T/N43K double mutant after 30 mins by CD spectroscopic analysis | Human immunodeficiency virus 1 | 3 | single protein format | Scientific Literature | ||
| 12. | ALA3602914 | B | Binding affinity to HIV1 NL4-3 gp41 N-terminal heptad repeat V38A/N42T double mutant after 30 mins by CD spectroscopic analysis | Human immunodeficiency virus 1 | 3 | single protein format | Scientific Literature | ||
| 13. | ALA4259332 | B | Inhibition of gp41 in HIV1 NL4-3 assessed as inhibition of viral infection in Ghost (3)X4/R5 cells after 48 hrs by Bright-Glo luciferase reporter gene assay | Human immunodeficiency virus 1 | 3 | cell-based format | Scientific Literature |
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