# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3630736 | Binding | Inhibition of NEK11 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay | Homo sapiens | 3 | ALA3627608 | single protein format | Scientific Literature | |
2. | ALA3748019 | Binding | Inhibition of human NEK11 using MBP as substrate | Homo sapiens | 1 | ALA3745707 | single protein format | Scientific Literature | |
3. | ALA3777726 | Binding | Inhibition of N-terminal His6-tagged recombinant human NEK11 expressed in baculovirus infected insect Sf9 cells assessed as remaining activity at 1 uM relative to control | Homo sapiens | 3 | ALA3774357 | cell-based format | Scientific Literature | |
4. | ALA3817589 | Binding | Inhibition of human NEK11 at 1 uM using MBP as substrate | Homo sapiens | 1 | ALA3813650 | single protein format | Scientific Literature | |
5. | ALA941788 | Binding | Inhibition of NEK11 | 1 | ALA1140564 | single protein format | Scientific Literature | ||
6. | ALA1174940 | Binding | Inhibition of NEK11 at 10 uM | 2 | ALA1177794 | single protein format | Scientific Literature | ||
7. | ALA4351982 | Binding | Inhibition of recombinant full-length human NEK11 at 10 uM using myelin basic protein as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation counting method | Homo sapiens | 1 | ALA4350961 | single protein format | Scientific Literature | |
8. | ALA4352465 | Binding | Inhibition of human NEK11 at 10 uM using MBP as substrate in presence of [gamma-33P]-ATP | Homo sapiens | 1 | ALA4350963 | single protein format | Scientific Literature | |
9. | ALA4358017 | Binding | Binding affinity to wild-type human partial length NEK11 (M1 to E313 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4354843 | assay format | Scientific Literature | |
10. | ALA1908422 | Binding | Binding constant for NEK11 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
11. | ALA1043344 | Binding | Residual activity of NEK11 at 0.1 uM by microplate scintillation counting | 3 | ALA1152560 | single protein format | Scientific Literature | ||
12. | ALA1041156 | Binding | Residual activity of NEK11 at 1 uM by microplate scintillation counting | 3 | ALA1152560 | single protein format | Scientific Literature | ||
13. | ALA1050309 | Binding | Residual activity of NEK11 at 10 uM by microplate scintillation counting | 3 | ALA1152560 | single protein format | Scientific Literature | ||
14. | ALA1054301 | Binding | Inhibition of NEK11 at 1 uM | 1 | ALA1154027 | single protein format | Scientific Literature | ||
15. | ALA1043879 | Binding | Binding affinity to NEK11 assessed as percentage of kinase remaining bound to the bead at 1 uM by T7 phage display based binding assay | 1 | ALA1154183 | single protein format | Scientific Literature | ||
16. | ALA922014 | Binding | Activity of human NEK11 kinase at 1 uM | Homo sapiens | 1 | ALA1147076 | single protein format | Scientific Literature | |
17. | ALA1646218 | Binding | Inhibition of human NEK11 at 10 uM after 60 mins by TR-FRET assay | Homo sapiens | 1 | ALA1641539 | single protein format | Scientific Literature | |
18. | ALA2174413 | Binding | Inhibition of NEK11 at 1 uM by 33P kinase hotspot assay | 2 | ALA2169801 | single protein format | Scientific Literature | ||
19. | ALA2215434 | Binding | Inhibition of NEK11 assessed as residual activity at 10 uM relative to control | 1 | ALA2203081 | single protein format | Scientific Literature | ||
20. | ALA2219299 | Binding | Millipore: Percentage of residual kinase activity of NEK11 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA | Homo sapiens | 158 | ALA2218924 | single protein format | Scientific Literature |