| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA900768 | B | Binding affinity to HBcAg | Hepatitis B virus | 2 | single protein format | Scientific Literature | ||
| 2. | ALA3364314 | B | Inhibition of hepatitis B virus capsid assembly after 24 hrs by HPLC analysis | Hepatitis B virus | 1 | assay format | Scientific Literature | ||
| 3. | ALA4012527 | B | Inhibition of HBV capsid assembly infected in human HepG2(2.2.15) cells assessed as inhibition of intracellular viral DNA level after 8 days by agarose gel electrophoresis method | Hepatitis B virus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4134182 | B | Inhibition of HBV C150-Bodipy FL N-(2-aminoethyl) maleimide labeled capsid assessed as reduction in NaCl-induced capsid assembly preincubated for 15 mins followed by NaCl addition measured after 1 hr by fluorescence quenching assay | Hepatitis B virus | 3 | single protein format | Scientific Literature | ||
| 5. | ALA4145308 | B | Induction of HBV Maleimidyl BoDIPY-FL-labeled capsid Cp*150 mutant aggregation incubated for 30 mins measured every 10 secs for 30 mins by fluorescence quenching assay | Hepatitis B virus | 18 | single protein format | Scientific Literature | ||
| 6. | ALA4177852 | B | Inhibition of reverse transcriptase M204I/S202G double mutant expressing entecavir-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4177855 | B | Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by real time PCR analysis | Hepatitis B virus | 52 | cell-based format | Scientific Literature | ||
| 8. | ALA4177867 | B | Inhibition of lamivudine-resistant wild type hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4177868 | B | Inhibition of reverse transcriptase M204I mutant expressing lamivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4177869 | B | Inhibition of reverse transcriptase M204I/V173L double mutant expressing lamivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4177870 | B | Inhibition of reverse transcriptase M204I mutant expressing lamivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4177871 | B | Inhibition of lamivudine-resistant wild type hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4177872 | B | Inhibition of reverse transcriptase M204I/VI73L double mutant expressing lamivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4177877 | B | Inhibition of reverse transcriptase M204I mutant expressing telbivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4177878 | B | Inhibition of reverse transcriptase L180M/M204V double mutant expressing telbivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4177879 | B | Inhibition of reverse transcriptase M204I mutant expressing telbivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4177880 | B | Inhibition of reverse transcriptase L180M/M204V double mutant expressing telbivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4177885 | B | Inhibition of reverse transcriptase M204I/S202G/M250V triple mutant expressing entecavir-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4177886 | B | Inhibition of reverse transcriptase M204I/S202G double mutant expressing entecavir-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4177887 | B | Inhibition of reverse transcriptase M204I/S202G/M250V triple mutant expressing entecavir-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | cell-based format | Scientific Literature |
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