# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA900768 | Binding | Binding affinity to HBcAg | Hepatitis B virus | 2 | ALA1137576 | single protein format | Scientific Literature | |
2. | ALA3364314 | Binding | Inhibition of hepatitis B virus capsid assembly after 24 hrs by HPLC analysis | Hepatitis B virus | 1 | ALA3352024 | assay format | Scientific Literature | |
3. | ALA4416859 | Binding | Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysis | Hepatitis B virus | 22 | ALA4414644 | cell-based format | Scientific Literature | |
4. | ALA4012527 | Binding | Inhibition of HBV capsid assembly infected in human HepG2(2.2.15) cells assessed as inhibition of intracellular viral DNA level after 8 days by agarose gel electrophoresis method | Hepatitis B virus | 1 | ALA4011615 | cell-based format | Scientific Literature | |
5. | ALA4134182 | Binding | Inhibition of HBV C150-Bodipy FL N-(2-aminoethyl) maleimide labeled capsid assessed as reduction in NaCl-induced capsid assembly preincubated for 15 mins followed by NaCl addition measured after 1 hr by fluorescence quenching assay | Hepatitis B virus | 3 | ALA4130455 | single protein format | Scientific Literature | |
6. | ALA4145308 | Binding | Induction of HBV Maleimidyl BoDIPY-FL-labeled capsid Cp*150 mutant aggregation incubated for 30 mins measured every 10 secs for 30 mins by fluorescence quenching assay | Hepatitis B virus | 18 | ALA4138314 | single protein format | Scientific Literature | |
7. | ALA4177852 | Binding | Inhibition of reverse transcriptase M204I/S202G double mutant expressing entecavir-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | ALA4177524 | cell-based format | Scientific Literature | |
8. | ALA4177855 | Binding | Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by real time PCR analysis | Hepatitis B virus | 52 | ALA4177524 | cell-based format | Scientific Literature | |
9. | ALA4177867 | Binding | Inhibition of lamivudine-resistant wild type hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | ALA4177524 | cell-based format | Scientific Literature | |
10. | ALA4177868 | Binding | Inhibition of reverse transcriptase M204I mutant expressing lamivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | ALA4177524 | cell-based format | Scientific Literature | |
11. | ALA4177869 | Binding | Inhibition of reverse transcriptase M204I/V173L double mutant expressing lamivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | ALA4177524 | cell-based format | Scientific Literature | |
12. | ALA4177870 | Binding | Inhibition of reverse transcriptase M204I mutant expressing lamivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | ALA4177524 | cell-based format | Scientific Literature | |
13. | ALA4177871 | Binding | Inhibition of lamivudine-resistant wild type hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | ALA4177524 | cell-based format | Scientific Literature | |
14. | ALA4177872 | Binding | Inhibition of reverse transcriptase M204I/VI73L double mutant expressing lamivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | ALA4177524 | cell-based format | Scientific Literature | |
15. | ALA4177877 | Binding | Inhibition of reverse transcriptase M204I mutant expressing telbivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | ALA4177524 | cell-based format | Scientific Literature | |
16. | ALA4177878 | Binding | Inhibition of reverse transcriptase L180M/M204V double mutant expressing telbivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | ALA4177524 | cell-based format | Scientific Literature | |
17. | ALA4177879 | Binding | Inhibition of reverse transcriptase M204I mutant expressing telbivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | ALA4177524 | cell-based format | Scientific Literature | |
18. | ALA4177880 | Binding | Inhibition of reverse transcriptase L180M/M204V double mutant expressing telbivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | ALA4177524 | cell-based format | Scientific Literature | |
19. | ALA4177885 | Binding | Inhibition of reverse transcriptase M204I/S202G/M250V triple mutant expressing entecavir-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | ALA4177524 | cell-based format | Scientific Literature | |
20. | ALA4177886 | Binding | Inhibition of reverse transcriptase M204I/S202G double mutant expressing entecavir-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels measured on day 7 by real-time PCR analysis | Hepatitis B virus | 1 | ALA4177524 | cell-based format | Scientific Literature |