# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2045967 | B | Inhibition of recombinant AKR1B10 assessed as NADP+ dependent reduction of DL-glyceraldehyde by fluorescence assay | 10 | single protein format | Scientific Literature | |||
2. | ALA2045968 | B | Inhibition of recombinant AKR1B10 assessed as NADP+ dependent reduction of DL-glyceraldehyde at 50 uM by fluorescence assay | 2 | single protein format | Scientific Literature | |||
3. | ALA921547 | B | Inhibition of retinaldehyde reductase activity of human AKR1B10 expressed in COS7 cells at 1 uM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA921548 | B | Inhibition of retinaldehyde reductase activity of human AKR1B10 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
5. | ALA921551 | B | Activity of human wild type AKR1B10 by BSA/HPLC method | Homo sapiens | 3 | single protein format | Scientific Literature | ||
6. | ALA921552 | B | Ratio of Kcat to Km for human wild type AKR1B10 | Homo sapiens | 3 | single protein format | Scientific Literature | ||
7. | ALA921553 | B | Activity of human AKR1B10 K125L mutant by BSA/HPLC method | Homo sapiens | 3 | single protein format | Scientific Literature | ||
8. | ALA921554 | B | Ratio of Kcat to Km for human AKR1B10 K125L mutant | Homo sapiens | 3 | single protein format | Scientific Literature | ||
9. | ALA921555 | B | Activity of human AKR1B10 V301L mutant by BSA/HPLC method | Homo sapiens | 3 | single protein format | Scientific Literature | ||
10. | ALA921556 | B | Ratio of Kcat to Km for human AKR1B10 V301L mutant | Homo sapiens | 3 | single protein format | Scientific Literature | ||
11. | ALA921557 | B | Activity of human AKR1B10 K125L/V301L mutant by BSA/HPLC method | Homo sapiens | 3 | single protein format | Scientific Literature | ||
12. | ALA921558 | B | Ratio of Kcat to Km for human AKR1B10 K125L/V301L mutant | Homo sapiens | 3 | single protein format | Scientific Literature | ||
13. | ALA921561 | B | Activity of human wild type AKR1B10 by by Tween 80 / spectrophotometer method | Homo sapiens | 2 | single protein format | Scientific Literature | ||
14. | ALA921562 | B | Activity of human AKR1B10 K125L mutant by by Tween 80 / spectrophotometer method | Homo sapiens | 2 | single protein format | Scientific Literature | ||
15. | ALA1944092 | B | Competitive inhibition at human recombinant N-terminus His6-tagged AKR1B10 Gln303Ser mutant expressed in Escherichia coli BL21 DE3 assessed as inhibition of NADP+ linked geraniol oxidation by fluorescence analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
16. | ALA1944093 | B | Competitive inhibition at human recombinant N-terminus His6-tagged AKR1B10 Ser304Ala mutant expressed in Escherichia coli BL21 DE3 assessed as inhibition of NADP+ linked geraniol oxidation by fluorescence analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
17. | ALA1944094 | B | Competitive inhibition at human recombinant N-terminus His6-tagged AKR1B10 Val301Leu/Gln303Ser double mutant expressed in Escherichia coli BL21 DE3 assessed as inhibition of NADP+ linked geraniol oxidation by fluorescence analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
18. | ALA1944095 | B | Ratio of Ki for human recombinant N-terminus His6-tagged AKR1B10 Gln114Thr mutant to Ki for human recombinant N-terminus His6-tagged AKR1B10 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
19. | ALA1944096 | B | Ratio of Ki for human recombinant N-terminus His6-tagged AKR1B10 Phe123Ala mutant to Ki for human recombinant N-terminus His6-tagged AKR1B10 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
20. | ALA1944097 | B | Ratio of Ki for human recombinant N-terminus His6-tagged AKR1B10 Trp220Tyr mutant to Ki for human recombinant N-terminus His6-tagged AKR1B10 | Homo sapiens | 1 | single protein format | Scientific Literature |