# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA893728 | B | Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 mins | Homo sapiens | 32 | ALA1147934 | cell-based format | Scientific Literature | |
2. | ALA1056061 | B | Inhibition of survivin | 2 | ALA1154630 | single protein format | Scientific Literature | ||
3. | ALA1777033 | B | Inhibition of survivin in human HCC-827 cells at 5 uM after up to 48 hrs by Western blotting | Homo sapiens | 1 | ALA1773023 | cell-based format | Scientific Literature | |
4. | ALA1777034 | B | Inhibition of survivin in human MDA-MB-468 cells at 5 uM after up to 48 hrs by Western blotting | Homo sapiens | 1 | ALA1773023 | cell-based format | Scientific Literature | |
5. | ALA2427878 | B | Modulation of GFP-tagged survivin dimerization in HUVEC assessed as defect in mitotic progression at 10 nM after 48 hrs by real-time video microscopy | Homo sapiens | 2 | ALA2424513 | single protein format | Scientific Literature | |
6. | ALA2427879 | B | Modulation of GFP-tagged survivin dimerization in human PC3 cells assessed as defect in mitotic progression at 10 nM after 72 hrs by real-time video microscopy | Homo sapiens | 2 | ALA2424513 | cell-based format | Scientific Literature | |
7. | ALA2427880 | B | Modulation of GFP-tagged survivin dimerization in HUVEC assessed as reduction in cell number at 50 to 100 nM by real-time video microscopy | Homo sapiens | 2 | ALA2424513 | single protein format | Scientific Literature | |
8. | ALA2427881 | B | Modulation of GFP-tagged survivin dimerization in HUVEC assessed as reduction in cell number after 48 hrs by real-time video microscopy | Homo sapiens | 2 | ALA2424513 | single protein format | Scientific Literature | |
9. | ALA2427882 | B | Modulation of GFP-tagged survivin dimerization in HUVEC assessed as time length of mitosis at 100 nM after 48 hrs by real-time video microscopy (Rvb = 51.2 +/- 2.3 mins) | Homo sapiens | 2 | ALA2424513 | single protein format | Scientific Literature | |
10. | ALA2427883 | B | Modulation of GFP-tagged survivin dimerization in human PC3 cells assessed as reduction in cell number at 50 to 100 nM after 72 hrs by real-time video microscopy relative to control | Homo sapiens | 1 | ALA2424513 | cell-based format | Scientific Literature | |
11. | ALA2427884 | B | Modulation of GFP-tagged survivin dimerization in HUVEC assessed as reduction in cell number at 50 to 100 nM after 48 hrs by real-time video microscopy relative to control | Homo sapiens | 1 | ALA2424513 | single protein format | Scientific Literature | |
12. | ALA2427885 | B | Modulation of GFP-tagged survivin dimerization in HUVEC assessed as defect in mitotic progression at 50 to 100 nM after 48 hrs by real-time video microscopy relative to control | Homo sapiens | 3 | ALA2424513 | single protein format | Scientific Literature | |
13. | ALA2427886 | B | Modulation of GFP-tagged survivin dimerization in human PC3 cells assessed as defect in mitotic progression at 50 to 100 nM after 72 hrs by real-time video microscopy | Homo sapiens | 3 | ALA2424513 | cell-based format | Scientific Literature | |
14. | ALA2427887 | B | Modulation of GFP-tagged survivin dimerization in HUVEC assessed as distorted, diffused or decondensed CPC organization at 10 nM after 48 hrs by real-time video microscopy relative to control | Homo sapiens | 2 | ALA2424513 | single protein format | Scientific Literature | |
15. | ALA2428073 | B | Modulation of GFP-tagged survivin dimerization in HUVEC assessed as distorted, diffused or decondensed CPC organization at 50 to 100 nM after 48 hrs by real-time video microscopy relative to control | Homo sapiens | 2 | ALA2424513 | single protein format | Scientific Literature | |
16. | ALA2428074 | B | Modulation of GFP-tagged survivin dimerization in human PC3 cells assessed as distorted, diffused or decondensed CPC organization at 50 to 100 nM after 72 hrs by real-time video microscopy relative to control | Homo sapiens | 2 | ALA2424513 | cell-based format | Scientific Literature | |
17. | ALA2428075 | B | Modulation of GFP-tagged survivin dimerization in human PC3 cells assessed as distorted, diffused or decondensed CPC organization at 10 nM after 72 hrs by real-time video microscopy relative to control | Homo sapiens | 2 | ALA2424513 | cell-based format | Scientific Literature | |
18. | ALA2445688 | B | Inhibition of survivin (unknown origin) | Homo sapiens | 1 | ALA2439991 | single protein format | Scientific Literature | |
19. | ALA3626271 | B | Activation of survivin in human Jurkat cells assessed as survivin phosphorylation at Thr32 residue at 0.1 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3621137 | cell-based format | Scientific Literature | |
20. | ALA4009888 | B | Binding affinity to survivin (unknown origin) after 20 mins by spectrofluorimetric titration method | Homo sapiens | 1 | ALA4007449 | single protein format | Scientific Literature |