| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA928592 | B | Inhibition of CXCR6 upto 1 uM | 1 | single protein format | Scientific Literature | |||
| 2. | ALA1952673 | B | Activity at human CXCR6 receptor at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA2328019 | B | Antagonist activity at CXCR6 (unknown origin) assessed as inhibition of chemotaxis at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA2328612 | F | Antagonist activity at CXCR6 (unknown origin) assessed as inhibition of calcium flux at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA2328632 | B | Binding affinity to CXCR6 (unknown origin) at 10 uM by radioligand displacement assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA3097204 | B | Inhibition of CXCR6 (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA5251599 | B | Binding affinity to CXCR6 (unknown origin) at 10 uM by radioligand binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA5257247 | B | Antagonist activity at CXCR6 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4028348 | F | Antagonist activity at human CXCR6 at 10 uM preincubated for 30 mins followed agonist addition measured after 30 to 60 mins by cAMP assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4037575 | B | Agonist activity at CXCR6 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA4037592 | B | Antagonist activity at CXCR6 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA4611266 | B | Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of CXCL16-induced beta-arrestin recruitment by DiscoveRx cell based assay | Homo sapiens | 61 | cell-based format | Scientific Literature | ||
| 13. | ALA4611267 | B | Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of CXCL16-induced beta-arrestin recruitment by DiscoveRx cell based assay relative to control | Homo sapiens | 61 | cell-based format | Scientific Literature | ||
| 14. | ALA4611268 | F | Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of forskolin-induced cAMP accumulation by DiscoveRx cell based assay | Homo sapiens | 61 | cell-based format | Scientific Literature | ||
| 15. | ALA4611269 | F | Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of forskolin-induced cAMP accumulation by DiscoveRx cell based assay relative to control | Homo sapiens | 61 | cell-based format | Scientific Literature | ||
| 16. | ALA4611286 | B | Inhibition of CXCR6-mediated cell invasion in human SKHEP1 cells after 72 hrs by transwell assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA4630484 | B | Antagonist activity at human Gi/G0-coupled CXCR6 assessed as inhibition of CXCL16-induced beta arrestin2 recruitment at 500 nM preincubated for 30 mins followed by CXCL16 stimulation and measured after 90 to 180 mins by pathhunter assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA4883356 | B | PRESTO-Tango GPCRome screening (CXCR6) | 1 | single protein format | Donated Chemical Probes - SGC Frankfurt | |||
| 19. | ALA5033788 | F | Agonist activity against CXCR6 (unknown origin) assessed as induction of beta-arrestin 2 recruitment at 10 microM by beta arrestin assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA5033789 | F | Antagonist activity against CXCR6 (unknown origin) assessed as inhibition of beta-arrestin 2 recruitment at 10 microM by beta arrestin assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature |
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