# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1038363 | B | Inhibition of PEK | 1 | ALA1155349 | single protein format | Scientific Literature | ||
2. | ALA1049468 | B | Residual activity of EIF2AK3 at 0.1 uM by microplate scintillation counting | 3 | ALA1152560 | single protein format | Scientific Literature | ||
3. | ALA1037131 | B | Residual activity of EIF2AK3 at 1 uM by microplate scintillation counting | 3 | ALA1152560 | single protein format | Scientific Literature | ||
4. | ALA1044299 | B | Residual activity of EIF2AK3 at 10 uM by microplate scintillation counting | 3 | ALA1152560 | single protein format | Scientific Literature | ||
5. | ALA1072220 | B | Inhibition of PERK | 3 | ALA1157561 | single protein format | Scientific Literature | ||
6. | ALA1116753 | B | Inhibition of PEK at 5 uM | 1 | ALA1154316 | single protein format | Scientific Literature | ||
7. | ALA1168150 | B | Induction of PERK-mediated phosphorylation of eIF2alpha in human Hep3B cells at 2 to 10 uM after 1 to 6 hrs by Western blot analysis | Homo sapiens | 2 | ALA1165946 | cell-based format | Scientific Literature | |
8. | ALA1168151 | B | Induction of PERK-mediated phosphorylation of eIF2alpha in human Hep3B cells at 50 uM after 1 hr by Western blot analysis | Homo sapiens | 1 | ALA1165946 | cell-based format | Scientific Literature | |
9. | ALA1274177 | B | Inhibition of PERK | 1 | ALA1268909 | single protein format | Scientific Literature | ||
10. | ALA1614254 | F | PUBCHEM_BIOASSAY: Counterscreen assay for PERK inhibitors: Dose response cell-based high throughput screening assay to measure inhibition of PERK at 6 hours. (Class of assay: confirmatory) [Related pubchem assays: 1522, 1416 ] | Homo sapiens | 118 | ALA1201862 | cell-based format | PubChem BioAssays | |
11. | ALA1614023 | F | PUBCHEM_BIOASSAY: Dose response cell-based high-throughput screening assay to measure PERK inhibition. (Class of assay: confirmatory) [Related pubchem assays: 1416 ] | Homo sapiens | 118 | ALA1201862 | cell-based format | PubChem BioAssays | |
12. | ALA1670303 | B | Inhibition of pERK | 31 | ALA1667830 | single protein format | Scientific Literature | ||
13. | ALA1776303 | B | Inhibition of PERK assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 1 | ALA1773059 | single protein format | Scientific Literature | ||
14. | ALA1838132 | B | Inhibition of human PEK in HL60 cells lysate at 10 uM using post probe-labeling by LC-MS/MS analysis relative to control | Homo sapiens | 5 | ALA1833925 | cell-based format | Scientific Literature | |
15. | ALA1930969 | B | Inhibition of EIF2AK3 assessed as residual activity at 10 uM using [33P-ATP] by radiometric filter binding assay | 1 | ALA1926576 | single protein format | Scientific Literature | ||
16. | ALA1942756 | B | Inhibition of human PEK in HL-60 cells lysate assessed as reduction of labeling of acyl-phosphate ATP probe at 100 nM | Homo sapiens | 4 | ALA1938230 | cell-based format | Scientific Literature | |
17. | ALA2015476 | B | Inhibition of PEK at 10 uM | 1 | ALA2010722 | single protein format | Scientific Literature | ||
18. | ALA2015007 | B | Inhibition of EIF2AK3 assessed as residual activity at 10 uM relative to control | 1 | ALA2010643 | single protein format | Scientific Literature | ||
19. | ALA2015950 | B | Inhibition of EIF2AK3 assessed as residual activity at 1 uM relative to control | 1 | ALA2010643 | single protein format | Scientific Literature | ||
20. | ALA2174334 | B | Inhibition of EIF2AK3 using [33P]ATP at 0.5 uM by filter-binding assay | 1 | ALA2169801 | single protein format | Scientific Literature |