# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1049969 | B | Binding affinity to EPHB6 assessed as percentage of kinase remaining bound to the bead at 1 uM by T7 phage display based binding assay | 1 | ALA1154183 | single protein format | Scientific Literature | ||
2. | ALA1169217 | B | Inhibition of EPHB6 at 1 uM | 6 | ALA1165965 | single protein format | Scientific Literature | ||
3. | ALA1174407 | B | Inhibition of EPHB6 at 10 uM | 2 | ALA1177794 | single protein format | Scientific Literature | ||
4. | ALA1244824 | B | Binding affinity to EPHB6 | 7 | ALA1240346 | single protein format | Scientific Literature | ||
5. | ALA1826627 | B | Activity of EPHB6 kinase at 1 uM | 1 | ALA1821651 | single protein format | Scientific Literature | ||
6. | ALA1908654 | B | Binding constant for EPHB6 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
7. | ALA2211498 | B | Inhibition of EPHB6 | 1 | ALA2203257 | single protein format | Scientific Literature | ||
8. | ALA2214004 | B | Inhibition of EPHB6 assessed as residual activity at 10 uM relative to control | 1 | ALA2203081 | single protein format | Scientific Literature | ||
9. | ALA2329865 | B | Displacement of ephrin-B1-Fc from EphB6 receptor Fc ectodomain (unknown origin) after 1 hr by ELISA | Homo sapiens | 1 | ALA2321799 | single protein format | Scientific Literature | |
10. | ALA3112111 | B | Inhibition of EPHB6 (unknown origin) assessed as residual activity at 10 uM after 1 hr by qPCR analysis relative to control | Homo sapiens | 1 | ALA3108735 | single protein format | Scientific Literature | |
11. | ALA3366570 | B | Inhibition of EPHB6 (unknown origin) assessed as residual activity at 10 uM relative to control | Homo sapiens | 1 | ALA3352819 | single protein format | Scientific Literature | |
12. | ALA3738313 | B | Displacement of biotinylated ephrin-B1-Fc from EphB6 (unknown origin) preincubated for 1 hr followed by biotinylated-ephrin-B1-Fc addition measured after 4 hrs by ELISA | Homo sapiens | 1 | ALA3734669 | single protein format | Scientific Literature | |
13. | ALA3784722 | B | Inhibition of partial length human wild type EPHB6 expressed in mammalian expression system assessed as residual activity at 1 uM relative to control | Homo sapiens | 1 | ALA3779840 | assay format | Scientific Literature | |
14. | ALA3991708 | B | Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. | Homo sapiens | 237 | ALA3991601 | subcellular format | Kuster lab chemical proteomics drug profiling | |
15. | ALA4025125 | B | Inhibition of wild-type human partial length EPHB6 (Q634 to P948 residues) expressed in mammalian expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4024706 | assay format | Scientific Literature | |
16. | ALA4043936 | B | Inhibition of wild-type human partial length EPHB6 (Q634 to P948 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
17. | ALA4054968 | B | Inhibition of wild-type human partial length EPHB6 (Q634 to P948 residues) expressed in mammalian expression system assessed as residual activity at 50 nM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4052645 | assay format | Scientific Literature | |
18. | ALA4157015 | B | Binding affinity to wild-type human partial length EPHB6 (Q634 to P948 residues) expressed in mammalian expression system assessed as residual binding at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4152344 | assay format | Scientific Literature | |
19. | ALA4185794 | B | Binding affinity to wild-type human partial length EPHB6 (Q634 to P948 residues) expressed in HEK293 cells at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4184148 | cell-based format | Scientific Literature | |
20. | ALA4230694 | B | Binding affinity to wild-type human partial length EPHB6 (Q634 to P948 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4229344 | assay format | Scientific Literature |