# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3611101 | Binding | Inhibition of liver delta-5 desaturase (unknown origin) at 1 uM | Homo sapiens | 2 | ALA3608212 | assay format | Scientific Literature | |
2. | ALA3611102 | Binding | Inhibition of liver delta-5 desaturase (unknown origin) | Homo sapiens | 26 | ALA3608212 | assay format | Scientific Literature | |
3. | ALA1106893 | Binding | Inhibition of delta5 desaturase in human HepG2 cells assessed as [14C]eicosatrienoic acid to [14C]arachidonic acid conversion pretreated 15 mins before [14C]eicosatrienoic acid addition measured after 4 hrs by HPLC based scintillation assay | Homo sapiens | 1 | ALA1154928 | cell-based format | Scientific Literature | |
4. | ALA1272962 | Binding | Inhibition of Delta(5) fatty acid desaturase in human HepG2 cells | Homo sapiens | 1 | ALA1268980 | cell-based format | Scientific Literature | |
5. | ALA1839321 | Binding | Inhibition of delta-5 desaturase | 16 | ALA1833926 | single protein format | Scientific Literature | ||
6. | ALA1955205 | Binding | Inhibition of delta-5 desaturase expressed in HepG2 cells | 1 | ALA1949632 | cell-based format | Scientific Literature | ||
7. | ALA1943139 | Binding | Inhibition of human delta-5 desaturase activity in human HepG2 cells using [1-14C]-stearic acid tracer | Homo sapiens | 1 | ALA1938352 | cell-based format | Scientific Literature | |
8. | ALA1050578 | Binding | Binding affinity to delta-5 saturase in human HepG2 cells by whole cell assay | Homo sapiens | 1 | ALA1155314 | cell-based format | Scientific Literature | |
9. | ALA2154133 | Binding | Inhibition of human delta-5 desaturase activity expressed in human HEpG2 cells | Homo sapiens | 5 | ALA2150952 | cell-based format | Scientific Literature | |
10. | ALA3106733 | Binding | Inhibition of human delta-5 desaturase at 10 uM | Homo sapiens | 28 | ALA3102832 | single protein format | Scientific Literature | |
11. | ALA3108187 | Binding | Inhibition of human delta-5 desaturase at 10 uM | Homo sapiens | 27 | ALA3102759 | single protein format | Scientific Literature | |
12. | ALA4026560 | Binding | Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid addition measured after 3 hrs by TLC analysis | Homo sapiens | 19 | ALA4024749 | cell-based format | Scientific Literature | |
13. | ALA4268603 | Binding | Inhibition of delta-5 fatty acid desaturase (unknown origin) | Homo sapiens | 2 | ALA4265954 | single protein format | Scientific Literature | |
14. | ALA4433174 | Binding | Inhibition of D5D in human HepG2 cells using [14C]DGLA as substrate preincubated for 30 mins followed by substrate addition measured after 3 hrs | Homo sapiens | 2 | ALA4431397 | cell-based format | Scientific Literature | |
15. | ALA4433182 | Binding | Ratio of inhibition of D5D in human HepG2 cells preincubated for 30 mins followed by [14C]DGLA substrate addition measured after 3 hrs to inhibition of D5D in human HepG2 cells assessed as inhibition of [14C]AA production preincubated for 3 hrs followed by compound washout and addition of [14C]DGLA substrate measured after 4 hrs | Homo sapiens | 1 | ALA4431397 | cell-based format | Scientific Literature | |
16. | ALA4433183 | Binding | Inhibition of D5D in human HepG2 cells using [14C]DGLA as substrate assessed as suppression of [14C]AA production at 10 uM preincubated for 3 hrs followed by compound washout and addition of substrate measured after 4 hrs by liquid scintillation counting | Homo sapiens | 1 | ALA4431397 | cell-based format | Scientific Literature | |
17. | ALA4433192 | Binding | Binding affinity to recombinant wild type D5D (unknown origin) expressed in baculovirus at 5 to 25 nM after 150 mins by liquid scintillation counting | Homo sapiens | 1 | ALA4431397 | assay format | Scientific Literature | |
18. | ALA4837102 | Binding | Inhibition of Delta-5-desaturase (unknown origin) expressed in HEK2936E cell membrane incubated for 1 hr by DGLA-CoA and Arachidonyl-CoA mass spectrometric assay | Homo sapiens | 6 | ALA4834493 | cell membrane format | Scientific Literature | |
19. | ALA5260606 | Binding | Inhibition of human Delta 5 desaturase (unknown origin) expressed in human HepG2 cells | Homo sapiens | 1 | ALA5257153 | cell-based format | Scientific Literature | |
20. | ALA5260607 | Binding | Invivo inhibition of human Delta 5 desaturase in C57BL/6J mouse at 3 mg/kg, po relative to control | Homo sapiens | 1 | ALA5257153 | organism-based format | Scientific Literature |