| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA940049 | F | Agonist activity at human GLP2 receptor expressed in BHK cells assessed as cAMP accumulation | Homo sapiens | 1 | ALA1147050 | cell-based format | Scientific Literature | |
| 2. | ALA1952682 | B | Activity at human GLP2 receptor at 10 uM | Homo sapiens | 1 | ALA1949601 | single protein format | Scientific Literature | |
| 3. | ALA2161794 | F | Agonist activity at human GLP2R expressed in HEK293 cells assessed as stimulation of cAMP levels incubated for 6 hrs by multiple response element/cAMP response element (MRE/CRE)-driven reporter gene assay | Homo sapiens | 3 | ALA2157924 | cell-based format | Scientific Literature | |
| 4. | ALA2183156 | F | Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as increase in intracellular cAMP level at 1 to 10 uM after 30 mins in presence of GLP2 (11 to 33) | Homo sapiens | 1 | ALA2176875 | cell-based format | Scientific Literature | |
| 5. | ALA2183157 | B | Displacement of [125I]-Bolton Hunter labeled GLP2 from GLP-2R overexpressed in human SE302 cell membranes up to 100 uM after 2 hrs by gamma counter | Homo sapiens | 1 | ALA2176875 | cell-based format | Scientific Literature | |
| 6. | ALA2183158 | F | Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as increase in intracellular cAMP level at 1 to 10 uM after 30 mins in presence of GLP2 (3 to 33) | Homo sapiens | 1 | ALA2176875 | cell-based format | Scientific Literature | |
| 7. | ALA2183159 | B | Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as upward shift in GLP2-induced placental alkaline phosphatase activation measured on day 3 by Alamar Blue assay | Homo sapiens | 1 | ALA2176875 | cell-based format | Scientific Literature | |
| 8. | ALA2183160 | F | Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as increase in intracellular cAMP level at 10 uM after 30 mins in presence of GLP2 | Homo sapiens | 1 | ALA2176875 | cell-based format | Scientific Literature | |
| 9. | ALA2183161 | B | Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as leftward shift in GLP2-induced placental alkaline phosphatase activation measured on day 3 by Alamar Blue assay | Homo sapiens | 1 | ALA2176875 | cell-based format | Scientific Literature | |
| 10. | ALA2183162 | B | Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as decrease in GLP2 (11 to 33) EC50 at 10 uM measured on day 3 by Alamar Blue assay relative to control | Homo sapiens | 1 | ALA2176875 | cell-based format | Scientific Literature | |
| 11. | ALA2183163 | B | Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as decrease in GLP2 (3 to 33) EC50 at 10 uM measured on day 3 by Alamar Blue assay relative to control | Homo sapiens | 1 | ALA2176875 | cell-based format | Scientific Literature | |
| 12. | ALA2183164 | B | Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as decrease in GLP2 (11 to 33) EC50 at 1 uM measured on day 3 by Alamar Blue assay relative to control | Homo sapiens | 1 | ALA2176875 | cell-based format | Scientific Literature | |
| 13. | ALA2183165 | B | Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as decrease in GLP2 (3 to 33) EC50 at 1 uM measured on day 3 by Alamar Blue assay relative to control | Homo sapiens | 1 | ALA2176875 | cell-based format | Scientific Literature | |
| 14. | ALA2183166 | B | Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as change in GLP2 EC50 measured on day 3 by Alamar Blue assay relative to control | Homo sapiens | 1 | ALA2176875 | cell-based format | Scientific Literature | |
| 15. | ALA2183167 | B | Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as increase in GLP2 (11 to 33)-induced placental alkaline phosphatase activation at 10 uM measured on day 3 by Alamar Blue assay relative to control | Homo sapiens | 1 | ALA2176875 | cell-based format | Scientific Literature | |
| 16. | ALA2183168 | B | Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as increase in GLP2 (11 to 33)-induced placental alkaline phosphatase activation at 1 uM measured on day 3 by Alamar Blue assay relative to control | Homo sapiens | 1 | ALA2176875 | cell-based format | Scientific Literature | |
| 17. | ALA2183169 | B | Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as increase in GLP2 (3 to 33)-induced placental alkaline phosphatase activation at 10 uM measured on day 3 by Alamar Blue assay relative to control | Homo sapiens | 1 | ALA2176875 | cell-based format | Scientific Literature | |
| 18. | ALA2183170 | B | Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as increase in GLP2 (3 to 33)-induced placental alkaline phosphatase activation at 1 uM measured on day 3 by Alamar Blue assay relative to control | Homo sapiens | 1 | ALA2176875 | cell-based format | Scientific Literature | |
| 19. | ALA2183171 | B | Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as increase in GLP2 (11 to 33)-induced placental alkaline phosphatase activation at 10 uM measured on day 3 by Alamar Blue assay relative to GLP2 | Homo sapiens | 2 | ALA2176875 | cell-based format | Scientific Literature | |
| 20. | ALA2183172 | B | Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as GLP2 (3 to 33)-induced placental alkaline phosphatase activation at 10 uM measured on day 3 by Alamar Blue assay relative to GLP2 | Homo sapiens | 2 | ALA2176875 | cell-based format | Scientific Literature |
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