| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1038026 | B | Binding affinity to GPR30 | 2 | ALA1156808 | single protein format | Scientific Literature | ||
| 2. | ALA1049719 | B | Displacement of 1-{2-[4-(6-bromobenzo[1,3]dioxol-5- yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]ethyl}- 3-(3-iodo(125)-phenyl)urea from GPR30 in human Hec50 cells | Homo sapiens | 9 | ALA1156808 | cell-based format | Scientific Literature | |
| 3. | ALA1049720 | F | Agonist activity at GPR30 in human SKBr3 cells assessed as stimulation of calcium mobilization at 10 uM relative to 200 nM estradiol | Homo sapiens | 9 | ALA1156808 | cell-based format | Scientific Literature | |
| 4. | ALA1049721 | F | Antagonist activity at GPR30 in human SKBr3 cells assessed as inhibition of estradiol-induced calcium mobilization at 10 uM | Homo sapiens | 9 | ALA1156808 | cell-based format | Scientific Literature | |
| 5. | ALA1049724 | F | Agonist activity at GFP-tagged GPR30 expressed in COS7 cells assessed as PI3K activation at 10 uM by PIP3 localization based PH-RFP reporter gene assay relative to 10 nM estradiol | 9 | ALA1156808 | cell-based format | Scientific Literature | ||
| 6. | ALA1049725 | F | Antagonist activity at GFP-tagged GPR30 expressed in COS7 cells assessed as inhibition of estradiol-induced PI3K activation at 10 uM by PIP3 localization based PH-RFP reporter gene assay | 9 | ALA1156808 | cell-based format | Scientific Literature | ||
| 7. | ALA1220636 | B | Binding affinity to GPR30 in human Hec50 cells by competitive binding assay | Homo sapiens | 2 | ALA1212719 | cell-based format | Scientific Literature | |
| 8. | ALA1220639 | F | Antagonist activity at GPR30 in human SKBr3 cells assessed as inhibition of G1-mediated calcium mobilization | Homo sapiens | 1 | ALA1212719 | cell-based format | Scientific Literature | |
| 9. | ALA1220640 | F | Antagonist activity in GPR30-transfected COS7 cells assessed as inhibition of E2-mediated PI(3)K activation | Homo sapiens | 1 | ALA1212719 | cell-based format | Scientific Literature | |
| 10. | ALA1226307 | B | Displacement of E2-Alexa633 from GFP-tagged GPR30 expressed in COS7 cells at 10 uM by FACS | 1 | ALA1221181 | cell-based format | Scientific Literature | ||
| 11. | ALA1226308 | B | Displacement of E2-Alexa633 from GFP-tagged GPR30 expressed in COS7 cells by FACS | 2 | ALA1221181 | cell-based format | Scientific Literature | ||
| 12. | ALA1226313 | F | Agonist activity at GFP-tagged GPR30 expressed in COS7 cells assessed as half life for increase in intracellular calcium level at 1 nM by spectrofluorimetry | 2 | ALA1221181 | cell-based format | Scientific Literature | ||
| 13. | ALA1226314 | F | Agonist activity at GFP-tagged GPR30 expressed in COS7 cells assessed as half life for increase in intracellular calcium level at 1 uM by spectrofluorimetry | 1 | ALA1221181 | cell-based format | Scientific Literature | ||
| 14. | ALA1226319 | F | Agonist activity at GFP-tagged GPR30 expressed in COS7 cells assessed as half life for increase in intracellular calcium level by spectrofluorimetry | 2 | ALA1221181 | cell-based format | Scientific Literature | ||
| 15. | ALA1226401 | F | Agonist activity at GFP-tagged GPR30 expressed in COS7 cells assessed as PI3K activation at 1 nM by PIP3 nuclear accumulation assay | 1 | ALA1221181 | cell-based format | Scientific Literature | ||
| 16. | ALA1226404 | F | Agonist activity at GFP-tagged GPR30 expressed in COS7 cells assessed as PI3K activation at 10 nM by PIP3 nuclear accumulation assay | 1 | ALA1221181 | cell-based format | Scientific Literature | ||
| 17. | ALA1226405 | B | Binding affinity to mRFP1-tagged GPR30 expressed in COS7 cells coexpressing GFP-tagged ERalpha assessed as inhibition of E2-Alexa633 binding in nucleus at 1 uM by FACS | 2 | ALA1221181 | cell-based format | Scientific Literature | ||
| 18. | ALA1226407 | F | Agonist activity at GPR30 in human SK-BR-3 cells endogenously expressing only GPR30 assessed as PI3K activation at 10 nM by PIP3 nuclear accumulation assay | Homo sapiens | 1 | ALA1221181 | cell-based format | Scientific Literature | |
| 19. | ALA1226408 | F | Agonist activity at GPR30 in human MCF7 cells endogenously expressing both GPR30 and ER assessed as PI3K activation at 10 nM by PIP3 nuclear accumulation assay | Homo sapiens | 1 | ALA1221181 | cell-based format | Scientific Literature | |
| 20. | ALA2427815 | B | Inhibition of estrogen binding to GPR30 (unknown origin) | Homo sapiens | 2 | ALA2424594 | single protein format | Scientific Literature |
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