| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2061375 | B | Inhibition of GLUT4 mediated [3H]-2-DG uptake in human LNCAP cells at 5 uM after 30 mins by scintillation counting | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA948003 | B | Inhibition of human GLUT4-mediated 2-deoxyglucose uptake in human adipocytes at 20 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA1103148 | B | Inhibition of GLUT4 | 7 | single protein format | Scientific Literature | |||
| 4. | ALA2445337 | B | Induction of human myc epitope-tagged GLUT4 translocation to plasma membrane overexpressed in rat L6 cells at 25 uM after 8 hrs by immunocolorimetric analysis in presence of 23.5 mM D-glucose relative to insulin | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA3992750 | B | Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA4132898 | B | Antagonist activity at GLUT4 in human JJN3 cells assessed as reduction in [3H]2-deoxy-D-glucose uptake preincubated for 5 to 6 mins followed by [3H]2-deoxy-D-glucose addition measured after 4 to 6 mins | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4132903 | B | Antagonist activity at human GLUT4 expressed in HEK293 cells transfected with GLUT1 shRNA assessed as inhibition of [3H]2-deoxy-D-glucose uptake preincubated for 5 mins followed by [3H]2-deoxy-D-glucose addition and measured after 6 mins | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA4132909 | B | Antagonist activity at GLUT4 in human L363 cells assessed as reduction in MCL-1 protein expression at 15 uM after 18 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4132910 | B | Antagonist activity at GLUT4 in human JJN-3 cells assessed as reduction in MCL-1 protein expression at 15 uM after 18 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4132911 | B | Antagonist activity at GLUT4 in human L393 cells assessed as increase in sensitivity to ABT-199-induced cytotoxicity by measuring cell death at 10 uM after 72 hrs by CellTiter-Glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4132912 | B | Antagonist activity at GLUT4 in human JJN-3 cells assessed as increase in sensitivity to ABT-199-induced cytotoxicity by measuring cell death at 10 uM after 72 hrs by CellTiter-Glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4132913 | B | Antagonist activity at GLUT4 in multiple myeloma patient derived CD38+ and phyocerythrin-negative myeloma cells assessed as increase in sensitivity to ABT-199-induced cytotoxicity by measuring cell death at 10 uM after 48 hrs by CellTiter-Glo assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA4132914 | B | Antagonist activity at GLUT4 in human MM1S cells assessed as increase in sensitivity to dexamethasone-induced cytotoxicity by measuring cell death at 10 uM after 72 hrs by CellTiter-Glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4132915 | B | Antagonist activity at GLUT4 in multiple myeloma patient derived CD38+ and phyocerythrin-negative myeloma cells assessed as increase in sensitivity to dexamethasone-induced cytotoxicity by measuring cell death at 10 uM after 48 hrs by CellTiter-Glo assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA4132919 | B | Antagonist activity at GLUT4 in human MM1S cells assessed as increase in sensitivity to melphalan-induced cytotoxicity by measuring cell death at 10 uM after 72 hrs by CellTiter-Glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4257292 | B | Inhibition of human GluT4 expressed in HEK293 cells assessed as reduction in 3H]-deoxy-D-glucose uptake incubated for 30 mins by scintillation counting method | Homo sapiens | 356 | cell-based format | Patent Bioactivity Data | ||
| 17. | ALA4771739 | B | Inhibition of transport activity of human GLUT4 expressed in hexose transporter deficient W4000fgy1 erg4 yeast cells assessed as reduction in transporter-mediated [14C]-hexose uptake into cells at 100 uM measured after 10 mins by scintillation counting method relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA4771741 | B | Inhibition of transport activity of human GLUT4 expressed in hexose transporter deficient W4000fgy1 erg4 yeast cells assessed as reduction in transporter-mediated [14C]-hexose uptake into cells measured after 10 mins by scintillation counting method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 19. | ALA4880934 | B | Cell-based assay with CellTiter-Glo readout for ATP production with SLC2A4 | Homo sapiens | 2 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 20. | ALA5209607 | F | Inhibition of the Glucose Transporter (GLUT4, SLC2A4) as assessed by a FRET based flow cytometry assay using a genetically-encoded biosensor for measuring free glucose (FLII12Pglu-700uDelta6) in HEK293 JumpIN TRex SLC2A4 WT-OE cells (PubChem AID: 1794828) | Homo sapiens | 4 | cell-based format | RESOLUTE - Research Empowerment on Solute Carriers |
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