# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA933562 | B | Inhibition of human beta hexosaminidase | Homo sapiens | 2 | single protein format | Scientific Literature | ||
2. | ALA986741 | B | Increase in thermostability of beta Hex A betaR505Q mutant isolated from Sandhoff disease patient assessed as residual enzyme activity at 3 ug/ml at 37 degC after 30 mins relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
3. | ALA986742 | B | Pharmacological chaperone effect on beta Hex A beta-C137Y/C137Y mutant in fibroblasts from Sandhoff disease patient assessed as increase in HEX A activity at 3 ug/ml by immunoselection assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
4. | ALA986743 | B | Pharmacological chaperone effect on beta Hex A beta-C137Y/C137Y mutant in fibroblasts from Sandhoff disease patient assessed as increase in HEX A activity at 300 mg/ml by immunoselection assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
5. | ALA986744 | B | Pharmacological chaperone effect on beta Hex A beta-C137Y/C137Y mutant in fibroblasts from Sandhoff disease patient assessed as increase in HEX S activity at 3 ug/ml by immunoselection assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
6. | ALA986745 | B | Pharmacological chaperone effect on beta Hex A beta-C137Y/C137Y mutant in fibroblasts from Sandhoff disease patient assessed as increase in HEX S activity at 300 mg/ml by immunoselection assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
7. | ALA986746 | B | Pharmacological chaperone effect on beta Hex A beta-T150P/P417L mutant in fibroblasts from Sandhoff disease patient assessed as increase in HEX A activity at 3 ug/ml by immunoselection assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
8. | ALA986747 | B | Pharmacological chaperone effect on beta Hex A beta-T150P/P417L mutant in fibroblasts from Sandhoff disease patient assessed as increase in HEX A activity at 300 mg/ml by immunoselection assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
9. | ALA986748 | B | Pharmacological chaperone effect on beta Hex A beta-T150P/P417L mutant in fibroblasts from Sandhoff disease patient assessed as increase in HEX S activity at 3 ug/ml by immunoselection assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
10. | ALA986749 | B | Pharmacological chaperone effect on beta Hex A beta-T150P/P417L mutant in fibroblasts from Sandhoff disease patient assessed as increase in HEX S activity at 300 mg/ml by immunoselection assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
11. | ALA986754 | B | Pharmacological chaperone effect on beta Hex A beta-P417L/delta16kb mutant in fibroblasts from Sandhoff disease patient assessed as increase in HEX A activity at 3 ug/ml by immunoselection assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
12. | ALA983111 | B | Pharmacological chaperone effect on beta Hex A beta-P417L/delta16kb mutant in fibroblasts from Sandhoff disease patient assessed as increase in HEX A activity at 300 mg/ml by immunoselection assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
13. | ALA983112 | B | Pharmacological chaperone effect on beta Hex A beta-P417L/delta16kb mutant in fibroblasts from Sandhoff disease patient assessed as increase in HEX S activity at 3 ug/ml by immunoselection assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
14. | ALA983113 | B | Pharmacological chaperone effect on beta Hex A beta-P417L/delta16kb mutant in fibroblasts from Sandhoff disease patient assessed as increase in HEX S activity at 300 mg/ml by immunoselection assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
15. | ALA983118 | B | Pharmacological chaperone effect on beta Hex A beta-P504S/delta16kb mutant in fibroblasts from Sandhoff disease patient assessed as increase in HEX A activity at 3 ug/ml by immunoselection assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
16. | ALA983119 | B | Pharmacological chaperone effect on beta Hex A beta-P504S/delta16kb mutant in fibroblasts from Sandhoff disease patient assessed as increase in HEX A activity at 300 mg/ml by immunoselection assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
17. | ALA983120 | B | Pharmacological chaperone effect on beta Hex A beta-P504S/delta16kb mutant in fibroblasts from Sandhoff disease patient assessed as increase in HEX S activity at 3 ug/ml by immunoselection assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
18. | ALA983121 | B | Pharmacological chaperone effect on beta Hex A beta-P504S/delta16kb mutant in fibroblasts from Sandhoff disease patient assessed as increase in HEX S activity at 300 mg/ml by immunoselection assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
19. | ALA983122 | B | Activation of on beta Hex A beta C137Y/C137Y mutant in postnuclear supernatant of fibroblasts from Sandhoff disease patient assessed as increase in HEX A activity per mg of protein at 3 mg/ml by relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
20. | ALA983123 | B | Activation of on beta Hex A beta C137Y/C137Y mutant in postnuclear supernatant of fibroblasts from Sandhoff disease patient assessed as increase in HEX S activity per mg of protein at 3 mg/ml by relative to control | Homo sapiens | 1 | single protein format | Scientific Literature |