# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3537356 | ADME | Inhibition of recombinant human ABCC3 expressed in baculovirus infected insect Sf21 cell plasma membrane vesicles assessed as inhibition of transporter-mediated [3H]-estradiol-17beta-glucuronide uptake by liquid scintillation counting analysis | Homo sapiens | 10 | ALA3526024 | cell-based format | Scientific Literature | |
2. | ALA3537698 | ADME | Activity of recombinant human ABCC3 expressed in baculovirus infected insect Sf21 cell plasma membrane vesicles assessed as transporter-mediated drug uptake at 10 uM by liquid scintillation counting analysis in presence of ATP | Homo sapiens | 1 | ALA3526024 | cell-based format | Scientific Literature | |
3. | ALA3537701 | ADME | Activity of recombinant human ABCC3 expressed in baculovirus infected insect Sf21 cell plasma membrane vesicles assessed as transporter-mediated drug uptake by liquid scintillation counting analysis in presence of ATP | Homo sapiens | 1 | ALA3526024 | cell-based format | Scientific Literature | |
4. | ALA3537704 | ADME | Activity of recombinant human ABCC3 expressed in baculovirus infected insect Sf21 cell plasma membrane vesicles assessed as transporter-mediated drug uptake per mg of protein by liquid scintillation counting analysis in presence of ATP | Homo sapiens | 1 | ALA3526024 | cell-based format | Scientific Literature | |
5. | ALA3535470 | ADME | Inhibition of MRP3-mediated E2-17betaG transport in human MRP3 expressing HEK293 cells in presence of 15 uM E2-17betaG | Homo sapiens | 3 | ALA3526013 | cell-based format | Scientific Literature | |
6. | ALA3533748 | ADME | Drug uptake assessed as human MRP3-mediated drug transport using inside-out membrane vesicles by measuring +ATP/-ATP ratio by LC-MS/MS analysis | Homo sapiens | 2 | ALA3526031 | assay format | Scientific Literature | |
7. | ALA3533968 | ADME | Activity at MRP3 (unknown origin) expressed in baculovirus-infected HEK293 cells assessed as drug transport at 400 uM after 10 mins by reversed-phase HPLC analysis in presence of AMP | Homo sapiens | 1 | ALA3526030 | cell-based format | Scientific Literature | |
8. | ALA3533972 | ADME | Activity at MRP3 (unknown origin) expressed in baculovirus-infected HEK293 cells assessed as drug transport at 400 uM up to 20 mins by Michaelis-Menten plot analysis | Homo sapiens | 1 | ALA3526030 | cell-based format | Scientific Literature | |
9. | ALA3533974 | ADME | Activity at MRP3 (unknown origin) expressed in baculovirus-infected HEK293 cells assessed as drug transport after 10 mins by Michaelis-Menten plot analysis | Homo sapiens | 1 | ALA3526030 | cell-based format | Scientific Literature | |
10. | ALA3536905 | ADME | Inhibition of human MRP3-mediated estradiol-17beta-D-glucuronide formation using inside-out membrane vesicles by LC-MS/MS analysis | Homo sapiens | 2 | ALA3526031 | assay format | Scientific Literature | |
11. | ALA3530758 | ADME | Activity at MRP3 (unknown origin) expressed in baculovirus-infected HEK293 cells assessed as drug transport at 400 uM after 10 mins by reversed-phase HPLC analysis in presence of ATP | Homo sapiens | 2 | ALA3526030 | cell-based format | Scientific Literature | |
12. | ALA3530764 | ADME | Activity at MRP3 (unknown origin) expressed in baculovirus-infected HEK293 cells assessed as drug transport at 400 uM after 10 mins by reversed phase-HPLC analysis in presence of GSH | Homo sapiens | 1 | ALA3526030 | cell-based format | Scientific Literature | |
13. | ALA1743161 | ADME | Substrates of transporters of clinical importance in the absorption and disposition of drugs, MPR3 | Homo sapiens | 3 | ALA1743141 | single protein format | Scientific Literature | |
14. | ALA1743180 | ADME | Inhibitors of transporters of clinical importance in the absorption and disposition of drugs, MPR3 | Homo sapiens | 3 | ALA1743141 | single protein format | Scientific Literature | |
15. | ALA1692699 | Binding | Inhibition of MRP3 expressed in MDCK2 cells assessed as cell growth inhibition by calcein and pheophorbide A efflux assays | 1 | ALA1687850 | cell-based format | Scientific Literature | ||
16. | ALA1692721 | Binding | Activity at MRP3 | 4 | ALA1687850 | single protein format | Scientific Literature | ||
17. | ALA1692727 | Binding | Induction of MRP3 activity | 4 | ALA1687850 | single protein format | Scientific Literature | ||
18. | ALA940041 | Binding | Inhibition of human MRP3 expressed in MDCK2 cells assessed as increase in intracellular CMF fluorescence by CMFDA assay | Homo sapiens | 7 | ALA1147049 | cell-based format | Scientific Literature | |
19. | ALA940044 | Binding | Inhibition of human MRP3 expressed in MDCK2 cells assessed as increase in intracellular CMF fluorescence at 10 uM by CMFDA assay | Homo sapiens | 6 | ALA1147049 | cell-based format | Scientific Literature | |
20. | ALA940047 | Binding | Inhibition of human MRP3 expressed in MDCK2 cells assessed as increase in intracellular CMF fluorescence at 16.7 uM by CMFDA assay | Homo sapiens | 1 | ALA1147049 | cell-based format | Scientific Literature |