# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1058558 | Functional | Agonist activity at human NPFF1 receptor expressed in cells assessed as beta-galactosidase levels after 5 days | Homo sapiens | 8 | ALA1154595 | cell-based format | Scientific Literature | |
2. | ALA1058559 | Functional | Agonist activity at human NPFF1 receptor expressed in cells assessed as beta-galactosidase levels at 10 mM after 5 days | Homo sapiens | 13 | ALA1154595 | cell-based format | Scientific Literature | |
3. | ALA1058560 | Functional | Antagonist activity at human NPFF1 receptor expressed in HEK293T cells assessed as inhibition of PGE2-induced cAMP release | Homo sapiens | 3 | ALA1154595 | cell-based format | Scientific Literature | |
4. | ALA3387180 | Binding | Antagonist activity at human NPFF1 receptor expressed in CHO cells | Homo sapiens | 1 | ALA3351542 | cell-based format | Scientific Literature | |
5. | ALA3387182 | Binding | Agonist activity at human NPFF1 receptor | Homo sapiens | 1 | ALA3351542 | single protein format | Scientific Literature | |
6. | ALA3387184 | Binding | Displacement of [125I]YVP from human NPFF1 receptor expressed in CHO cells after 1 hr by liquid scintillation counting analysis | Homo sapiens | 14 | ALA3351542 | cell-based format | Scientific Literature | |
7. | ALA3387185 | Binding | Displacement of [3H]NPVF from human NPFF1 receptor expressed in CHO cells after 1 hr by liquid scintillation counting analysis | Homo sapiens | 25 | ALA3351542 | cell-based format | Scientific Literature | |
8. | ALA3387195 | Functional | Agonist activity at human NPFF1 receptor expressed in CHO cells at 10 uM after 60 mins by [35S-GTPgammaS] binding assay relative to control | Homo sapiens | 2 | ALA3351542 | cell-based format | Scientific Literature | |
9. | ALA3387752 | Functional | Agonist activity at human NPFF1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation up to 1 uM by liquid scintillation counting analysis | Homo sapiens | 1 | ALA3351542 | cell-based format | Scientific Literature | |
10. | ALA3387753 | Functional | Partial agonist activity at human NPFF1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation at >1 uM by liquid scintillation counting analysis | Homo sapiens | 1 | ALA3351542 | cell-based format | Scientific Literature | |
11. | ALA3387755 | Functional | Antagonist activity at human NPFF1 receptor expressed in CHO cells assessed as reversal of NPVF-induced inhibition of intracellular cAMP accumulation after 10 mins by liquid scintillation counting analysis relative to control | Homo sapiens | 3 | ALA3351542 | cell-based format | Scientific Literature | |
12. | ALA3387757 | Functional | Agonist activity at human NPFF1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation by liquid scintillation counting analysis | Homo sapiens | 2 | ALA3351542 | cell-based format | Scientific Literature | |
13. | ALA3387760 | Binding | Partial antagonist activity at human NPFF1 receptor expressed in CHO cells assessed NPVF EC50 at 10 uM after 10 mins by liquid scintillation counting analysis to NPVF EC50 alone | Homo sapiens | 1 | ALA3351542 | cell-based format | Scientific Literature | |
14. | ALA3388430 | Functional | Antagonist activity at human NPFF1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation relative to control | Homo sapiens | 1 | ALA3351542 | cell-based format | Scientific Literature | |
15. | ALA1681414 | Binding | Displacement of (D-[125I]Tyr1, MePhe3)-NPFF from NPFFR1 at 10 uM after 2 hrs | 2 | ALA1671829 | single protein format | Scientific Literature | ||
16. | ALA1681417 | Binding | Displacement of (D-[125I]Tyr1, MePhe3)-NPFF from NPFFR1 after 2 hrs | 4 | ALA1671829 | single protein format | Scientific Literature | ||
17. | ALA1681421 | Functional | Agonist activity at NPFFR1 expressed in HEK293T cells co-expressing Gqi5 assessed as increase of intracellular calcium mobilization after 1 hr | 2 | ALA1671829 | cell-based format | Scientific Literature | ||
18. | ALA1681551 | Functional | Agonist activity at NPFFR1 expressed in HEK293T cells co-expressing Gqi5 assessed as increase of intracellular calcium mobilization at 0.24 uM after 1 hr | 3 | ALA1671829 | cell-based format | Scientific Literature | ||
19. | ALA1681553 | Functional | Agonist activity at NPFFR1 expressed in HEK293T cells assessed as inhibition of forskolin-induced cAMP accumulation at up to 100 uM after 30 mins | 3 | ALA1671829 | cell-based format | Scientific Literature | ||
20. | ALA2166812 | Functional | Agonist activity at human NPFF1 receptor F/Y7.35A mutant assessed as [3H]inositol phosphate accumulation at 31.6 uM after 2 hrs by liquid scintillation counting relative to NPVF | Homo sapiens | 1 | ALA2163262 | assay format | Scientific Literature |