| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1058555 | F | Antagonist activity at human NPFF2 receptor expressed in HEK293T cells assessed as inhibition of PGE2-induced cAMP release | Homo sapiens | 2 | ALA1154595 | cell-based format | Scientific Literature | |
| 2. | ALA1058556 | F | Agonist activity at human NPFF2 receptor expressed in cells assessed as beta-galactosidase levels after 5 days | Homo sapiens | 11 | ALA1154595 | cell-based format | Scientific Literature | |
| 3. | ALA1058557 | F | Agonist activity at human NPFF2 receptor expressed in cells assessed as beta-galactosidase levels at 10 mM after 5 days | Homo sapiens | 13 | ALA1154595 | cell-based format | Scientific Literature | |
| 4. | ALA1681415 | B | Displacement of (D-[125I]Tyr1, MePhe3)-NPFF from NPFFR2 at 10 uM after 2 hrs | 2 | ALA1671829 | single protein format | Scientific Literature | ||
| 5. | ALA1681418 | B | Displacement of (D-[125I]Tyr1, MePhe3)-NPFF from NPFFR2 after 2 hrs | 4 | ALA1671829 | single protein format | Scientific Literature | ||
| 6. | ALA1681422 | F | Agonist activity at NPFFR2 expressed in HEK293T cells co-expressing Gqi5 assessed as increase of intracellular calcium mobilization after 1 hr | 2 | ALA1671829 | cell-based format | Scientific Literature | ||
| 7. | ALA1681552 | F | Agonist activity at NPFFR2 expressed in HEK293T cells assessed as inhibition of forskolin-induced cAMP accumulation at up to 100 uM after 30 mins | 3 | ALA1671829 | cell-based format | Scientific Literature | ||
| 8. | ALA2166786 | F | Partial agonist activity at human NPFF2 receptor F/Y7.35A mutant assessed as [3H]inositol phosphate accumulation at 10 uM after 2 hrs by liquid scintillation counting relative to NPFF | Homo sapiens | 1 | ALA2163262 | assay format | Scientific Literature | |
| 9. | ALA2166787 | F | Agonist activity at human NPFF2 receptor Y7.33A mutant assessed as [3H]inositol phosphate accumulation at 31.6 uM after 2 hrs by liquid scintillation counting relative to NPFF | Homo sapiens | 1 | ALA2163262 | assay format | Scientific Literature | |
| 10. | ALA2166788 | F | Agonist activity at human NPFF2 receptor D6.59A mutant assessed as [3H]inositol phosphate accumulation at 31.6 uM after 2 hrs by liquid scintillation counting relative to NPFF | Homo sapiens | 1 | ALA2163262 | assay format | Scientific Literature | |
| 11. | ALA2166789 | F | Agonist activity at human NPFF2 receptor Y5.38A mutant assessed as [3H]inositol phosphate accumulation at 31.6 uM after 2 hrs by liquid scintillation counting relative to NPFF | Homo sapiens | 1 | ALA2163262 | assay format | Scientific Literature | |
| 12. | ALA2166790 | F | Agonist activity at human NPFF2 receptor E5.27A mutant assessed as [3H]inositol phosphate accumulation at 31.6 uM after 2 hrs by liquid scintillation counting relative to NPFF | Homo sapiens | 2 | ALA2163262 | assay format | Scientific Literature | |
| 13. | ALA2166791 | F | Agonist activity at human NPFF2 receptor F/Y7.35A mutant assessed as [3H]inositol phosphate accumulation at 10 uM after 2 hrs by liquid scintillation counting relative to NPFF | Homo sapiens | 4 | ALA2163262 | assay format | Scientific Literature | |
| 14. | ALA2166792 | B | Ratio of EC50 for human NPFF2 receptor F/Y7.35A mutant to EC50 for human wild type NPFF2 receptor | Homo sapiens | 1 | ALA2163262 | single protein format | Scientific Literature | |
| 15. | ALA2166793 | F | Agonist activity at human NPFF2 receptor F/Y7.35A mutant assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation counting | Homo sapiens | 5 | ALA2163262 | assay format | Scientific Literature | |
| 16. | ALA2166794 | B | Ratio of EC50 for human NPFF2 receptor Y7.33A mutant to EC50 for human wild type NPFF2 receptor | Homo sapiens | 1 | ALA2163262 | single protein format | Scientific Literature | |
| 17. | ALA2166795 | F | Agonist activity at human NPFF2 receptor Y7.33A mutant assessed as [3H]inositol phosphate accumulation at 10 uM after 2 hrs by liquid scintillation counting relative to NPFF | Homo sapiens | 2 | ALA2163262 | assay format | Scientific Literature | |
| 18. | ALA2166796 | F | Agonist activity at human NPFF2 receptor Y7.33A mutant assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation counting | Homo sapiens | 3 | ALA2163262 | assay format | Scientific Literature | |
| 19. | ALA2166797 | F | Agonist activity at human NPFF2 receptor H/Q6.69A mutant assessed as [3H]inositol phosphate accumulation at 10 uM after 2 hrs by liquid scintillation counting relative to NPFF | Homo sapiens | 1 | ALA2163262 | assay format | Scientific Literature | |
| 20. | ALA2166798 | B | Ratio of EC50 for human NPFF2 receptor H/Q6.69A mutant to EC50 for human wild type NPFF2 receptor | Homo sapiens | 1 | ALA2163262 | single protein format | Scientific Literature |
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