| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA929914 | B | Inhibition of PAD4 by ABPP-based assay | 14 | single protein format | Scientific Literature | |||
| 2. | ALA929915 | B | Inhibition of PAD4 measured by slope plot of Lineweaver-Burke analyses | 3 | single protein format | Scientific Literature | |||
| 3. | ALA929916 | B | Inhibition of PAD4 measured by intercept plot of Lineweaver-Burke analyses | 3 | single protein format | Scientific Literature | |||
| 4. | ALA1912607 | B | Ratio of Kcat to Km for PAD4 Q346A mutant | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 5. | ALA1912608 | B | Ratio of Kcat to Km for PAD4 R347K mutant | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 6. | ALA1912609 | B | Ratio of Kcat to Km for PAD4 R347A mutant | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 7. | ALA1913983 | B | Irreversible inhibition of PAD4 assessed as residual activity at 1 mM measured after 20 hrs by colorimetric assay in presence of 2 mM benzoyl-L-arginine ethyl ester | 2 | single protein format | Scientific Literature | |||
| 8. | ALA1913987 | B | Irreversible inhibition of PAD4 assessed as residual activity at 1 mM measured after 20 hrs by colorimetric assay in presence of 10 mM benzoyl-L-arginine ethyl ester | 2 | single protein format | Scientific Literature | |||
| 9. | ALA1914038 | B | Ratio of Kinact to Ki for F-amidine to compound for PAD4 | 1 | single protein format | Scientific Literature | |||
| 10. | ALA1914041 | B | Ratio of Kinact to Ki for Cl-amidine to compound for PAD4 | 1 | single protein format | Scientific Literature | |||
| 11. | ALA1914011 | B | Irreversible inhibition of PAD4 assessed as hydrolysis of benzoyl-L-arginine ethyl ester preincubated for 15 mins measured after 15 mins by fluorometric analysis | 18 | single protein format | Scientific Literature | |||
| 12. | ALA1914104 | B | Irreversible inhibition of PAD4 assessed as residual activity at 1 mM measured after 20 hrs by colorimetric assay | 4 | single protein format | Scientific Literature | |||
| 13. | ALA1914108 | B | Irreversible inhibition of PAD4 assessed as residual activity measured after 20 hrs by colorimetric assay | 4 | single protein format | Scientific Literature | |||
| 14. | ALA1914113 | B | Irreversible inhibition of PAD4 Q346E mutant assessed as hydrolysis of benzoyl-L-arginine ethyl ester preincubated for 15 mins measured after 15 mins | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 15. | ALA1914114 | B | Irreversible inhibition of PAD4 Q346A mutant assessed as hydrolysis of benzoyl-L-arginine ethyl ester preincubated for 15 mins measured after 15 mins | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 16. | ALA1914115 | B | Irreversible inhibition of PAD4 R374K mutant assessed as hydrolysis of benzoyl-L-arginine ethyl ester preincubated for 15 mins measured after 15 mins | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 17. | ALA1914116 | B | Irreversible inhibition of PAD4 R374A mutant assessed as hydrolysis of benzoyl-L-arginine ethyl ester preincubated for 15 mins measured after 15 mins | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 18. | ALA1914117 | B | Ratio of Kcat to Km for PAD4 Q346E mutant | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 19. | ALA1914118 | B | Inhibition of PAD4 in calcium ionophore A23187 stimulated-human HL60 granulocytes assessed as reduction in deaminated histone H3 at 1 uM after 30 mins by Western blotting | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 20. | ALA1914154 | B | Inhibition of PAD4 in calcium ionophore A23187 stimulated-human HL60 granulocytes assessed as reduction in deaminated histone H3 at 100 uM after 48 hrs by Western blotting | Homo sapiens | 2 | assay format | Scientific Literature |
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