# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA945893 | B | Binding affinity to NQQ1 | 1 | single protein format | Scientific Literature | |||
2. | ALA1252135 | B | Induction of quinone reductase activity in human MCF7 cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
3. | ALA4119055 | B | Binding affinity to CRYZ in human NCI-H358 cells at 1 uM by mass spectrometry based pull down assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA4316692 | B | Inhibition of human Quinone oxidoreductase | Homo sapiens | 2 | single protein format | Scientific Literature | ||
5. | ALA4721796 | B | Covalent binding affinity to CRYZ at Cys45 residue in human NCI-H358 cells assessed as log2 H/L ratio at 10 uM pretreated for 3 hrs followed by N-(((6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl)methyl)-2-hydroxyacetamide treatment for 3 hrs by competitive TMT click chemistry pull-down experiment based LC-MS/MS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA4721806 | B | Covalent binding affinity to CRYZ at Cys45 residue in human NCI-H358 cells assessed as reduction of log2 H/L ratio for tryptic peptide VHACGVNPVETYIR incubated for 4 hrs followed by cell lysis and subsequently labelled with light thiol probe N-((S)-18-iodo-11-isopropyl-10,13,17-trioxo-3,6-dioxa-9,12,16-triazaoctadecyl)-6-((4R,5S)-5-methyl-2-oxoimidazolidin-4-yl)hexanamide and heavy thiol probe 4 for 1 hr under dark conditions followed by tryptic digestion for overnight and measured by discovery ABPP based nano LC-MS/MS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |