| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1826694 | B | Activity of QSK kinase at 1 uM | 1 | single protein format | Scientific Literature | |||
| 2. | ALA1908471 | B | Binding constant for QSK kinase domain | 72 | single protein format | Scientific Literature | |||
| 3. | ALA1043883 | B | Binding affinity to QSK assessed as percentage of kinase remaining bound to the bead at 1 uM by T7 phage display based binding assay | 1 | single protein format | Scientific Literature | |||
| 4. | ALA1166834 | B | Inhibition of QSK at 1 uM | 6 | single protein format | Scientific Literature | |||
| 5. | ALA1175244 | B | Inhibition of QSK at 10 uM | 2 | single protein format | Scientific Literature | |||
| 6. | ALA1244949 | B | Binding affinity to QSK | 7 | single protein format | Scientific Literature | |||
| 7. | ALA2211515 | B | Inhibition of KIAA0999 | 1 | single protein format | Scientific Literature | |||
| 8. | ALA2212019 | B | Inhibition of QSK assessed as residual activity at 10 uM relative to control | 1 | single protein format | Scientific Literature | |||
| 9. | ALA2214641 | B | Inhibition of SIK3 assessed as residual activity at 1 uM | 1 | single protein format | Scientific Literature | |||
| 10. | ALA2213184 | B | Inhibition of SIK3 assessed as residual activity at 10 uM | 1 | single protein format | Scientific Literature | |||
| 11. | ALA3388056 | B | Inhibition of SIK3 (unknown origin) assessed as remaining enzyme activity at 10 uM by radioactive [33P]-ATP filter binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA3631472 | B | Inhibition of SIK3 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 13. | ALA3750158 | B | Inhibition of human SIK3 using [AMARAASAAALARRR] as substrate | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA3829284 | B | Inhibition of human SIK3 (2 to 1369 residues) assessed as remaining enzyme activity at 50 uM after 30 mins by 33P-ATP filter-binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA3991880 | B | Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. | Homo sapiens | 242 | subcellular format | Kuster lab chemical proteomics drug profiling | ||
| 16. | ALA4025352 | B | Inhibition of wild-type human partial length QSK (A90 to L395 residues) expressed in mammalian expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA4044163 | B | Inhibition of wild-type human partial length QSK (A90 to L395 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4045816 | B | Inhibition of QSK conserved Lys1 (VAIKIIDKTQLDEENLKK) in human PBMC at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA4046057 | B | Inhibition of QSK conserved Lys1 (VAIKIIDKTQLDEENLKK) in human PBMC at 0.1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA4050365 | B | Inhibition of human SIK3 assessed as residual activity at 1 uM in presence of [33P]ATP by filter binding assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature |
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