# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1045672 | B | Binding affinity to YANK1 assessed as percentage of kinase remaining bound to the bead at 1 uM by T7 phage display based binding assay | 1 | ALA1154183 | single protein format | Scientific Literature | ||
2. | ALA1175121 | B | Inhibition of YANK1 at 10 uM | 2 | ALA1177794 | single protein format | Scientific Literature | ||
3. | ALA1908518 | B | Binding constant for YANK1 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
4. | ALA2209232 | B | Inhibition of YANK1 assessed as residual activity at 10 uM relative to control | 1 | ALA2203081 | single protein format | Scientific Literature | ||
5. | ALA3111558 | B | Inhibition of YANK1 (unknown origin) assessed as residual activity at 10 uM after 1 hr by qPCR analysis relative to control | Homo sapiens | 1 | ALA3108735 | single protein format | Scientific Literature | |
6. | ALA4025442 | B | Inhibition of wild-type human full length YANK1 (M1 to L396 residues) expressed in mammalian expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4024706 | assay format | Scientific Literature | |
7. | ALA4044253 | B | Inhibition of wild-type human full length YANK1 (M1 to L396 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
8. | ALA4055100 | B | Inhibition of wild-type human full length STK32A (M1 to L396 residues) expressed in mammalian expression system assessed as residual activity at 50 nM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4052645 | assay format | Scientific Literature | |
9. | ALA4157332 | B | Binding affinity to wild-type human full length YANK1 (M1 to L396 residues) expressed in mammalian expression system assessed as residual binding at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4152344 | assay format | Scientific Literature | |
10. | ALA4186111 | B | Binding affinity to wild-type human full length YANK1 (M1 to L396 residues) expressed in HEK293 cells at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4184148 | cell-based format | Scientific Literature | |
11. | ALA4191198 | B | Inhibition of recombinant full-length human STK32A at 1 uM using casein as substrate after 120 mins in presence of [gamma-33P]ATP by scintillation counting method | Homo sapiens | 1 | ALA4190187 | single protein format | Scientific Literature | |
12. | ALA4231011 | B | Binding affinity to wild-type human full length YANK1 (M1 to L396 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4229344 | assay format | Scientific Literature | |
13. | ALA4264600 | B | Binding affinity to wild-type human full length YANK1 (M1 to L396 residues) expressed in mammalian expression system assessed as remaining unbound target protein level at 1000 nM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4261600 | assay format | Scientific Literature | |
14. | ALA4308105 | B | Binding affinity to wild-type human full length YANK1 (M1 to L396 residues) expressed in mammalian expression system assessed as residual binding level at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4304811 | assay format | Scientific Literature | |
15. | ALA4314942 | B | Inhibition of recombinant full-length human STK32A assessed as residual activity at 10 uM using casein as substrate measured after 120 mins in presence of [gamma33P]ATP by scintillation counting method | Homo sapiens | 1 | ALA4311992 | single protein format | Scientific Literature | |
16. | ALA4322823 | B | Binding affinity to recombinant full-length N-terminal His-FLAG-tagged STK32A (unknown origin) expressed in baculovirus infected Sf9 insect cells incubated for 1 hr by TR-FRET assay | Homo sapiens | 2 | ALA4321812 | cell-based format | Scientific Literature | |
17. | ALA4333685 | B | Binding affinity to wild-type human full length YANK1 (M1 to L396 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4330132 | assay format | Scientific Literature | |
18. | ALA4335300 | B | Inhibition of recombinant full-length human STK32A at 1 uM assessed as residual activity at 1 uM using casein as substrate measured after 120 mins in presence of [gamma33P]ATP by scintillation counting method relative to control | Homo sapiens | 2 | ALA4334438 | single protein format | Scientific Literature | |
19. | ALA4337125 | B | Inhibition of recombinant human full length STK32A assessed as residual activity at 10 uM using casein as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | ALA4334471 | single protein format | Scientific Literature | |
20. | ALA4352074 | B | Inhibition of recombinant full-length human STK32A at 10 uM using casein as substrate measured after 120 mins in presence of [gamma33P]ATP by scintillation counting method | Homo sapiens | 1 | ALA4350961 | single protein format | Scientific Literature |