# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3631232 | Binding | Inhibition of 6-His tagged recombinant human glyoxalase 1 transfected in Escherichia coli BL21 (DE3) assessed as S-D-lactoylglutathione formation by spectrophotometer | Homo sapiens | 2 | ALA3627636 | assay format | Scientific Literature | |
2. | ALA3631235 | Binding | Inhibition of human glyoxalase 1 | Homo sapiens | 5 | ALA3627636 | single protein format | Scientific Literature | |
3. | ALA3631239 | Binding | Potency index, ratio of CHG Ki to compound Ki for human glyoxalase 1 | Homo sapiens | 2 | ALA3627636 | single protein format | Scientific Literature | |
4. | ALA684427 | Binding | Binding affinity on yeast glyoxalase I (GlxI) was determined | Fungi | 4 | ALA1133474 | single protein format | Scientific Literature | |
5. | ALA684991 | Binding | Binding affinity for Glyoxalase I | Homo sapiens | 11 | ALA1133474 | single protein format | Scientific Literature | |
6. | ALA684992 | Binding | Tested for inhibitory activity against human erythrocyte glyoxalase I | 4 | ALA1127571 | single protein format | Scientific Literature | ||
7. | ALA684997 | Functional | In vivo inhibitory activity against glyoxalase I in sheep liver; no inhibition | Ovis aries | 1 | ALA1122424 | organism-based format | Scientific Literature | |
8. | ALA684998 | Binding | Tested for inhibitory activity against yeast glyoxalase I | Saccharomyces cerevisiae | 9 | ALA1127571 | single protein format | Scientific Literature | |
9. | ALA684310 | Binding | Inhibition constant of compound against binding of Yeast Glyoxalase I | Saccharomyces cerevisiae | 41 | ALA1124156 | single protein format | Scientific Literature | |
10. | ALA857390 | Binding | Compound was evaluated for inhibition of Saccharomyces cerevisiae glyoxalase-I, activity i determined with 0.5 mM substrate | Saccharomyces cerevisiae | 2 | ALA1131657 | single protein format | Scientific Literature | |
11. | ALA686107 | Binding | Compound was evaluated for inhibition of Saccharomyces cerevisiae glyoxalase-I, activity is determined with 0.5 mM substrate | Saccharomyces cerevisiae | 3 | ALA1131657 | single protein format | Scientific Literature | |
12. | ALA686108 | Binding | Compound was evaluated for inhibition of Saccharomyces cerevisiae glyoxalase-I by using enzymatic assay at each of 6 substrate concentrations between 0.1 mM and 2.0 mM | Saccharomyces cerevisiae | 3 | ALA1131657 | single protein format | Scientific Literature | |
13. | ALA686109 | Binding | Compound was evaluated for inhibition of Saccharomyces cerevisiae glyoxalase-I by using enzymatic assay at each of 6 substrate concentrations between 0.1 mM and 2.0 mM; Not Determined | Saccharomyces cerevisiae | 2 | ALA1131657 | single protein format | Scientific Literature | |
14. | ALA821876 | Binding | Ability to inhibit yeast glyoxalase I enzyme in 0.05 M phosphate buffer, pH 6.6, 30 degree C | Saccharomyces cerevisiae | 2 | ALA1132077 | single protein format | Scientific Literature | |
15. | ALA828914 | Binding | Inhibitory constant against Glyoxalase I | Homo sapiens | 1 | ALA1144323 | single protein format | Scientific Literature | |
16. | ALA1251073 | Binding | Inhibition of human recombinant glyoxalase 1 assessed as S-D-lactoylglutathione after 15 mins by spectrophotometric analysis | Homo sapiens | 4 | ALA1250526 | single protein format | Scientific Literature | |
17. | ALA1799085 | Binding | Inhibition of human glyoxalase 1 | Homo sapiens | 7 | ALA1795301 | single protein format | Scientific Literature | |
18. | ALA1913551 | Binding | Inhibition of recombinant human His-tagged glyoxalase 1 expressed in Escherichia coli BL21 assessed as formation of S-D-lactoylglutathione after 5 mins by spectrophotometric method | Homo sapiens | 5 | ALA1909515 | assay format | Scientific Literature | |
19. | ALA1913552 | Binding | Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 assessed as formation of S-D-lactoylglutathione at 100 uM after 5 mins by spectrophotometric method | Homo sapiens | 3 | ALA1909515 | assay format | Scientific Literature | |
20. | ALA1670272 | Binding | Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysis | Homo sapiens | 31 | ALA1667824 | assay format | Scientific Literature |