# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA945801 | B | Binding affinity to alpha-synuclein fibrils by fluorescent titration | 2 | single protein format | Scientific Literature | |||
2. | ALA2065090 | B | Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
3. | ALA2065091 | B | Inhibition of human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells at 3 uM after 1 hr by thioflavin T fluorescence assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
4. | ALA2065092 | B | Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells assessed as fibril dissociation at 3 uM after 1 hr by SyPRO Ruby gel staining analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
5. | ALA1218779 | B | Inhibition of alpha-synuclein-mediated toxicity in yeast transfected with human alpha-synuclein by spotting assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
6. | ALA1218780 | B | Inhibition of human alpha-synuclein-mediated accumulation of stalled vesicle pools in yeast transfected with human alpha-synuclein after 8 to 12 hrs by electron microscopy | Homo sapiens | 2 | assay format | Scientific Literature | ||
7. | ALA1218781 | B | Inhibition of alpha-synuclein-mediated dopaminergic neurodegeneration in Caenorhabditis elegans transfected with human alpha-synuclein | Homo sapiens | 4 | assay format | Scientific Literature | ||
8. | ALA1250260 | B | Induction of alpha-synuclein aggregation in PBS buffer assessed as fluorescence after 48 hrs by Thioflavin T fluorescence assay | 2 | single protein format | Scientific Literature | |||
9. | ALA1250261 | B | Induction of alpha-synuclein aggregation in PBS buffer assessed as fluorescence after 72 hrs by Thioflavin T fluorescence assay | 2 | single protein format | Scientific Literature | |||
10. | ALA1250262 | B | Induction of alpha-synuclein aggregation in PBS buffer assessed as fluorescence after 96 hrs by Thioflavin T fluorescence assay | 2 | single protein format | Scientific Literature | |||
11. | ALA1250263 | B | Induction of alpha-synuclein aggregation in PBS buffer assessed as fluorescence after 330 hrs by Thioflavin T fluorescence assay | 2 | single protein format | Scientific Literature | |||
12. | ALA1250264 | B | Induction of alpha-synuclein aggregation in PBS buffer assessed as transition of alpha-synuclein from natively unfolded monomer to cross-beta-sheet conformation after 48 hrs by CD spectroscopy | 2 | single protein format | Scientific Literature | |||
13. | ALA1250265 | B | Induction of alpha-synuclein aggregation in PBS buffer assessed as transition of alpha-synuclein from natively unfolded monomer to cross-beta-sheet conformation after 72 hrs by CD spectroscopy | 1 | single protein format | Scientific Literature | |||
14. | ALA1250266 | B | Induction of alpha-synuclein aggregation in PBS buffer assessed as transition of alpha-synuclein from natively unfolded monomer to cross-beta-sheet conformation after 96 hrs by CD spectroscopy | 2 | single protein format | Scientific Literature | |||
15. | ALA1250267 | B | Induction of alpha-synuclein aggregation in PBS buffer assessed as transition of alpha-synuclein from natively unfolded monomer to cross-beta-sheet conformation after 330 hrs by CD spectroscopy | 2 | single protein format | Scientific Literature | |||
16. | ALA1250268 | B | Induction of alpha-synuclein aggregation in PBS buffer assessed as alpha-synuclein monomer depletion after 48 hrs by size exclusion chromatography | 2 | single protein format | Scientific Literature | |||
17. | ALA1250269 | B | Induction of alpha-synuclein aggregation in PBS buffer assessed as alpha-synuclein monomer depletion after 72 hrs by size exclusion chromatography | 1 | single protein format | Scientific Literature | |||
18. | ALA1250270 | B | Induction of alpha-synuclein aggregation in PBS buffer assessed as alpha-synuclein monomer depletion after 96 hrs by size exclusion chromatography | 2 | single protein format | Scientific Literature | |||
19. | ALA1250271 | B | Induction of alpha-synuclein aggregation in PBS buffer assessed as formation of alpha-synuclein fibrils after 48 hrs by electron microscopy | 1 | single protein format | Scientific Literature | |||
20. | ALA1250272 | B | Induction of alpha-synuclein aggregation in PBS buffer assessed as formation of alpha-synuclein fibrils after 96 hrs by electron microscopy | 1 | single protein format | Scientific Literature |