# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA886345 | B | Inhibition of UCHL3 at 20 uM | Homo sapiens | 2 | ALA1139949 | single protein format | Scientific Literature | |
2. | ALA940889 | B | Inhibition of human UCH-L3 hydrolysis activity | Homo sapiens | 4 | ALA1139799 | single protein format | Scientific Literature | |
3. | ALA940890 | B | Inhibition of human UCH-L3 hydrolysis activity at 401 uM relative to control | Homo sapiens | 2 | ALA1139799 | single protein format | Scientific Literature | |
4. | ALA940891 | B | Inhibition of human UCH-L3 hydrolysis activity at 375 uM relative to control | Homo sapiens | 1 | ALA1139799 | single protein format | Scientific Literature | |
5. | ALA940892 | B | Inhibition of human UCH-L3 hydrolysis activity at 350 uM relative to control | Homo sapiens | 1 | ALA1139799 | single protein format | Scientific Literature | |
6. | ALA940893 | B | Inhibition of human UCH-L3 hydrolysis activity at 334 uM | Homo sapiens | 1 | ALA1139799 | single protein format | Scientific Literature | |
7. | ALA940894 | B | Inhibition of human UCH-L3 hydrolysis activity at 331 uM | Homo sapiens | 1 | ALA1139799 | single protein format | Scientific Literature | |
8. | ALA940895 | B | Inhibition of human UCH-L3 hydrolysis activity at 386 uM | Homo sapiens | 1 | ALA1139799 | single protein format | Scientific Literature | |
9. | ALA940896 | B | Inhibition of human UCH-L3 hydrolysis activity at 387 uM | Homo sapiens | 1 | ALA1139799 | single protein format | Scientific Literature | |
10. | ALA940897 | B | Inhibition of human UCH-L3 hydrolysis activity at 380 uM relative to control | Homo sapiens | 1 | ALA1139799 | single protein format | Scientific Literature | |
11. | ALA1243700 | B | Inhibition of UCHL3 in human H1299 cells | Homo sapiens | 6 | ALA1240332 | cell-based format | Scientific Literature | |
12. | ALA1243704 | B | Inhibition of UCHL3 | 1 | ALA1240332 | single protein format | Scientific Literature | ||
13. | ALA2411921 | B | Inhibition of human UCH-L3 using Ub-AMC as substrate at 1 to 30 uM after 60 mins by fluorometric analysis | Homo sapiens | 1 | ALA2406999 | single protein format | Scientific Literature | |
14. | ALA4119765 | B | Inhibition of UCH-L3 (unknown origin) using Ub-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluorescence based assay | Homo sapiens | 1 | ALA4118084 | single protein format | Scientific Literature | |
15. | ALA4358863 | B | Inhibition of human recombinant UCHL3 assessed as reduction in cleavage of luminescent substrate Ub-AML at 100 uM | Homo sapiens | 1 | ALA4354861 | single protein format | Scientific Literature | |
16. | ALA4372599 | B | Inhibition of UCHL3 in HEK293T cell lysates at 25 uM using HA-tagged vinyl-sulfone as substrate preincubated for 19 to 60 mins followed by substrate addition and measured after 19 to 25 mins by Western blot analysis | Homo sapiens | 1 | ALA4371052 | subcellular format | Scientific Literature | |
17. | ALA4372609 | B | Inhibition of UCHL3 in HEK293T cell lysates at 25 uM using HA-tagged vinyl-sulfone as substrate measured after 2 to 30 mins by Western blot analysis | Homo sapiens | 1 | ALA4371052 | subcellular format | Scientific Literature | |
18. | ALA4372616 | B | Inhibition of UCHL3 in HEK293T cell lysates assessed as enzyme recovery at 250 uM using HA-tagged vinyl-sulfone as substrate preincubated for 40 mins followed by 10-fold dilution and subsequent substrate addition measured within 15 mins by Western blot analysis | Homo sapiens | 1 | ALA4371052 | subcellular format | Scientific Literature | |
19. | ALA4605971 | B | Inhibition of human GST-tagged UCHL3 expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine110-glycine using Ubiquitin-Rhodamine110-glycine as substrate by fluorescence based analysis | Homo sapiens | 3 | ALA4602719 | assay format | Scientific Literature | |
20. | ALA4688789 | B | Inhibition of recombinant human UCHL3 assessed as reduction in cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine110-glycine using Ub-Rho 110 as substrate incubated for 30 mins by fluorescence based assay | Homo sapiens | 1 | ALA4680319 | single protein format | Scientific Literature |