| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1050760 | F | Agonist activity at mouse GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation by scintillation proximity assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA3734280 | F | Agonist activity at GLP1 receptor in mouse BetaTC6 cells assessed as increase in insulin release at 20 ug/ml incubated for 2 hrs by ELISA | Mus musculus | 2 | cell-based format | Patent Bioactivity Data | ||
| 3. | ALA3993853 | B | Antagonist activity at GLP-1R in C57BL/6J mouse primary islets assessed as inhibition of exendin-4-induced increase in glucose-stimulated insulin secretion at 1 uM after 60 mins by radio-immunoassay | Mus musculus | 2 | single protein format | Scientific Literature | ||
| 4. | ALA4047993 | B | Agonist activity at GLP1 receptor in mouse BetaTC6 cells assessed as increase in insulin secretion at 10'-12 to 10'-5 M after 120 mins by sandwich ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4047994 | B | Agonist activity at GLP1 receptor in mouse BetaTC6 cells assessed as increase in glucose-dependent insulin secretion at 10'-12 to 10'-5 M after 120 mins by sandwich ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4047995 | B | Agonist activity at GLP1 receptor in mouse BetaTC6 cells assessed as increase in insulin secretion at 10'-15 to 10'-12 M after 120 mins by sandwich ELISA | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4047996 | B | Agonist activity at GLP1 receptor in mouse BetaTC6 cells assessed as increase in glucose-dependent insulin secretion at 10'-15 M after 120 mins by sandwich ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4047997 | B | Agonist activity at GLP1 receptor in mouse BetaTC6 cells assessed as increase in glucose-dependent insulin secretion at 10'-15 to 10'-9 M after 120 mins by sandwich ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4047998 | B | Agonist activity at GLP1 receptor in mouse BetaTC6 cells assessed as increase in insulin secretion at 10'-15 to 10'-9 M after 120 mins by sandwich ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4047999 | B | Agonist activity at GLP1 receptor in mouse BetaTC6 cells assessed as increase in glucose-dependent insulin secretion after 120 mins by sandwich ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4052177 | F | Agonist activity at mouse GLP-1 receptor expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assay | Mus musculus | 5 | cell-based format | Scientific Literature | ||
| 12. | ALA4220174 | F | Agonist activity at mouse GLP1 receptor expressed in CHO cells assessed as increase in cAMP level by TR-FRET assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4356187 | F | Positive allosteric modulator activity at GLP-1R in mouse MIN6-c4 cells assessed as effect on glucose-mediated increase in intracellular Ca2+ level by FLIPR assay relative to control | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA4356196 | F | Positive allosteric modulator activity at mouse GLP-1R expressed in PSC-HEK293 cells in presence of EC20 level of GLP1(9-36)NH2 incubated for 30 mins by HTRF cAMP assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4356197 | F | Positive allosteric modulator activity at mouse GLP-1R expressed in PSC-HEK293 cells in presence of EC20 level of GLP1(9-36)NH2 incubated for 30 mins by HTRF cAMP assay relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4356211 | F | Inhibition of 15 mM glucose-mediated increase in intracellular Ca2+ level in mouse MIN6-c4 cells at 0.12 to 30 uM by FLIPR assay relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4356212 | F | Inhibition of 15 mM glucose-mediated increase in intracellular Ca2+ level in mouse MIN6-c4 cells at 30 uM by FLIPR assay relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4808901 | F | Antagonist activity at mouse GLP1R expressed in CHO-K1 cells assessed as inhibition of GLP1-induced cAMP production | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA4808902 | F | Antagonist activity at mouse GLP1R expressed in CHO-K1 cells assessed as inhibition of GLP1-induced cAMP production relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA5168520 | F | Activation of mouse GLP-1R expressed in CHO cells assessed as increase in cAMP accumulation | Mus musculus | 1 | cell-based format | Scientific Literature |
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